DENAMIC
Developmental neurotoxicity assessment of mixtures in children
| Coordinatore | STICHTING VU-VUMC
Organization address
address: DE BOELELAAN 1105 contact info |
| Nazionalità Coordinatore | Netherlands [NL] |
| Totale costo | 9˙245˙375 € |
| EC contributo | 6˙993˙863 € |
| Programma | FP7-ENVIRONMENT
Specific Programme "Cooperation": Environment (including Climate Change) |
| Code Call | FP7-ENV-2011 |
| Funding Scheme | CP-IP |
| Anno di inizio | 2012 |
| Periodo (anno-mese-giorno) | 2012-01-01 - 2015-12-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
STICHTING VU-VUMC
Organization address
address: DE BOELELAAN 1105 contact info |
NL (AMSTERDAM) | coordinator | 1˙559˙968.40 |
| 2 |
UNIVERSITEIT UTRECHT
Organization address
address: Heidelberglaan 8 contact info |
NL (UTRECHT) | participant | 1˙070˙228.50 |
| 3 |
UPPSALA UNIVERSITET
Organization address
address: SANKT OLOFSGATAN 10 B contact info |
SE (UPPSALA) | participant | 747˙180.80 |
| 4 |
FUNDACION DE LA COMUNIDAD VALENCIANA CENTRO DE INVESTIGACION PRINCIPE FELIPE
Organization address
address: CALLE EDUARDO PRIMO YUFERA 3 contact info |
ES (VALENCIA) | participant | 649˙130.00 |
| 5 |
Nome Ente NON disponibile
Organization address
address: Catedratico Agustin Escardino 9 contact info |
ES (Paterna) | participant | 530˙960.00 |
| 6 |
Proteome Sciences R&D GmbH & Co. KG
Organization address
city: Frankfurt contact info |
DE (Frankfurt) | participant | 530˙033.00 |
| 7 |
CENTRO SUPERIOR DE INVESTIGACION EN SALUD PUBLICA
Organization address
address: Avenida de Cataluna 21 contact info |
ES (Valencia) | participant | 463˙472.40 |
| 8 |
NASJONALT FOLKEHELSEINSTITUTT
Organization address
address: Lovisenberggata 8 contact info |
NO (OSLO) | participant | 438˙200.00 |
| 9 |
Masarykova univerzita
Organization address
address: Zerotinovo namesti 9 contact info |
CZ (BRNO STRED) | participant | 424˙344.75 |
| 10 |
VIEW POINT SA
Organization address
address: ALLEE DES CHEVREUILS 3 contact info |
FR (LISSIEU) | participant | 235˙834.00 |
| 11 |
CALLISTO PRODUCTIONS LTD
Organization address
address: Carolines Crescent contact info |
UK ("ELLON, ABBERDEENSHIRE") | participant | 167˙000.00 |
| 12 |
SLOVENSKA ZDRAVOTNICKA UNIVERZITA V BRATISLAVE
Organization address
address: LIMBOVA 12 contact info |
SK (BRATISLAVA) | participant | 65˙155.25 |
| 13 |
GEN-INFO ZA USLUGE D.O.O.
Organization address
address: RUZMARINKA 17 contact info |
HR (ZAGREB) | participant | 59˙856.30 |
| 14 |
INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU ELECTROCHIMIE SI MATERIE CONDENSATA - INCEMC TIMISOARA
Organization address
address: AUREL PAUNESCU PODEANU 144 contact info |
RO (TIMISOARA) | participant | 52˙500.00 |
| 15 |
VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG
Organization address
address: De Boelelaan 1105 contact info |
NL (AMSTERDAM) | participant | 0.00 |
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Obiettivo del progetto (Objective)
'Various recent epidemiological studies have indicated that exposure to low doses of environmental biologically active contaminants during human development can alter gene expression and have deleterious effects on cognitive development in childhood. The DENAMIC project is ultimately focused on reducing such effects of environmental contamination on learning and developmental disorders in children. It aims to study and evaluate environment-health relationships in children. Key elements are: development of sophisticated tools and methods for early warning and screening of compounds for neurotoxicity, to study mechanisms of disease development and the role of individual susceptibility, to improve assessment of exposures and effects, focus on combined exposures to environmental agents that can interact to enhance adverse effects and reduction of health inequalities of children through Europe. One of the main aims of DENAMIC is to develop tools and methods for neurotoxic effects of mixtures of environmental pollutants at low levels, possibly resulting in (subclinical) effects on learning (cognitive skills) and developmental disorders in children (e.g ADHD, autism spectrum disorders and anxiety disorders). A broad suite of contaminants will be included in the studies, with options to bring in new chemicals in case evidence comes up during the project. With 14 partners from ten different countries DENAMIC has a true international character. It is a comprehensive, multi-disciplinary project. Six SME’s will play a key role in the development of biotechnological screening tools. The most modern techniques in the fields of genomics, proteomics, metabolomics and transcriptomics will be applied. Dissemination will ensure the project results to arrive at policymakers' desks, and will also illustrate the subject for a scientific audience and the public. The very large network of the consortium ensures dissemination to European industries, and every other interested stakeholder.'
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