BIOELECTRICSURFACE

Electrically modified biomaterials surface

 Coordinatore UNIVERSITY OF LIMERICK 

 Organization address address: NATIONAL TECHNOLOGICAL PARK, PLASSEY
city: LIMERICK
postcode: -

contact info
Titolo: Dr.
Nome: Syed A. M.
Cognome: Tofail
Email: send email
Telefono: -233840
Fax: -213237

 Nazionalità Coordinatore Ireland [IE]
 Sito del progetto http://www.bioelectricsurface.eu
 Totale costo 4˙996˙254 €
 EC contributo 3˙540˙643 €
 Programma FP7-NMP
Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies
 Code Call FP7-NMP-2007-SMALL-1
 Funding Scheme CP-FP
 Anno di inizio 2008
 Periodo (anno-mese-giorno) 2008-10-01   -   2011-09-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSITY OF LIMERICK

 Organization address address: NATIONAL TECHNOLOGICAL PARK, PLASSEY
city: LIMERICK
postcode: -

contact info
Titolo: Dr.
Nome: Syed A. M.
Cognome: Tofail
Email: send email
Telefono: -233840
Fax: -213237

IE (LIMERICK) coordinator 0.00
2    AKADEMIA MEDYCZNA IM PIASTOW SLASKICH WE WROCLAWIU AM WROCLAW

 Organization address address: UL PASTEURA 1
city: WROCLAW
postcode: 50 367

contact info
Titolo: Prof.
Nome: Walentyna
Cognome: Mazurek
Email: send email
Telefono: -7842634
Fax: -3270984

PL (WROCLAW) participant 0.00
3    BALTON SPOLKA ZOO

 Organization address address: NOWY SWIAT 7 M 14
city: WARSZAWA
postcode: 00 496

contact info
Titolo: Mr.
Nome: Leszek
Cognome: Hurkala
Email: send email
Telefono: -5974392
Fax: -5974418

PL (WARSZAWA) participant 0.00
4    BEN-GURION UNIVERSITY OF THE NEGEV

 Organization address address: Office of the President - Main Campus
city: BEER SHEVA
postcode: 84105

contact info
Titolo: Prof.
Nome: Sidney
Cognome: Lang
Email: send email
Telefono: -6460526
Fax: -6471952

IL (BEER SHEVA) participant 0.00
5    BeoCare Limited

 Organization address address: PARK ROAD
city: KILLARNEY
postcode: N/A

contact info
Titolo: Mr.
Nome: Eoin
Cognome: Collins
Email: send email
Telefono: -39111
Fax: -39121

IE (KILLARNEY) participant 0.00
6    COOK IRELAND LIMITED

 Organization address address: O HALLORAN ROAD
city: LIMERICK
postcode: n/a

contact info
Titolo: Mr.
Nome: Shay
Cognome: Lavelle
Email: send email
Telefono: -239016
Fax: -334149

IE (LIMERICK) participant 0.00
7    NATIONAL UNIVERSITY OF IRELAND, GALWAY

 Organization address address: University Road -
city: GALWAY

contact info
Titolo: Dr.
Nome: Gerard
Cognome: Wall
Email: send email
Telefono: -495546
Fax: -494336

IE (GALWAY) participant 0.00
8    PETER BREHM

 Organization address address: AM MUHLBERG 30
city: WEISENDORF
postcode: 91085

contact info
Titolo: Dr.
Nome: Bernhard
Cognome: Kleffner
Email: send email
Telefono: -719418
Fax: -719469

DE (WEISENDORF) participant 0.00
9    POLITECHNIKA WROCLAWSKA

 Organization address address: WYBRZEZE WYSPIANSKIEGO 27
city: WROCLAW
postcode: 50370

contact info
Titolo: Prof.
Nome: Halina
Cognome: Podbielska
Email: send email
Telefono: -3202548
Fax: -3277750

PL (WROCLAW) participant 0.00
10    TECHNISCHE UNIVERSITAET DRESDEN

 Organization address address: HELMHOLTZSTRASSE 10
city: DRESDEN
postcode: 1069

contact info
Titolo: Mr.
Nome: Sven
Cognome: Kreigenfeld
Email: send email
Telefono: -46340046
Fax: -46340046

DE (DRESDEN) participant 0.00
11    TEKNOLOGISK INSTITUT

 Organization address address: GREGERSENSVEJ 1
city: TAASTRUP
postcode: 2630

contact info
Nome: Naseem
Cognome: Theilgaard
Email: send email
Telefono: -203154
Fax: -203139

DK (TAASTRUP) participant 0.00
12    UNIVERSITATEA POLITEHNICA DIN BUCURESTI

 Organization address address: SPLAIUL INDEPENDENTEI 313
city: BUCURESTI
postcode: 60042

contact info
Titolo: Prof.
Nome: George
Cognome: Stanciu
Email: send email
Telefono: -4029091
Fax: -4029091

RO (BUCURESTI) participant 0.00
13    UNIVERZITA KOMENSKEHO V BRATISLAVE

 Organization address address: SAFARIKOVO NAM 6
city: Bratislava 1
postcode: 81499

contact info
Titolo: Prof.
Nome: Andrej
Cognome: Plecenik
Email: send email
Telefono: -65424563
Fax: -65425463

SK (Bratislava 1) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

surfaces    almost    urological    interactions    electrically    huge    nanoscale    doubled    death    related    earnings    years    nanometer    market    organisation    stents    suffer    world    deaths    biological    team    biomaterial    cardiovascular    ageing    health    last    bio    electrical    implants    density    decade    surface    labour    biomaterials    interaction    family    half    modification    pressure    according    strategic    techniques    charge    nano    fractures    bone    women    osteoporosis    biomedical    modified    diseases    force    population    nanotechnology   

 Obiettivo del progetto (Objective)

'According to the World Health Organisation (WHO), cardiovascular diseases cause half the deaths in the EU. It is also the main cause of years of life lost (over 30 per cent) in early death thus causing huge pressure on the labour force and family earnings. The problem is becoming more acute in Central and Eastern European countries. Due to the ageing population in the EU, osteoporosis related bone fractures have almost doubled in the last decade. It is estimated that 40 percent of women over 50 years in age will suffer from fractures due to low density bone. The European Commission considers the application of nanotechnology an important research strategy to address these problems. For this, design and control of biomaterial at the nanometer scale is set as a strategic research priority. Europe is, however, seriously under-represented in the global market for nanotherapeutics, where the United States dominates with three-quarter of the market share. While the drive for nanoscale understanding of biological interaction can be high, the application of this knowledge in marketable devices should also be prioritised. Here, we propose electrical modification of biomaterials surface to manipulate surface charge that will mediate bio/non bio interactions in vivo. We propose novel nanoscale techniques to probe this surface charge at the nanometer scale so that we have a quantitative insight to biological interaction at the biomedical device surfaces. Such an approach will help us to scale up electrical modification in cardiovascular stents, urological stents, orthopedic implants and photosterilisation devices. The research proposed here will not only provide nanoscale understanding of biological interactions on biomaterials surface but also result in novel applications and devices, which will penetrate into the market in short to medium term.'

Introduzione (Teaser)

European and Israeli scientists have joined forced to investigate biomaterials used to treat sufferers of cardiovascular diseases and osteoporosis.

Descrizione progetto (Article)

According to the World Health Organisation (WHO), cardiovascular disease is responsible for over half of all deaths in the EU and puts huge pressure on the labour force and family earnings. Meanwhile, due to the ageing population in the EU, osteoporosis-related bone fractures have almost doubled in the last decade - it is estimated that 40;% of women over 50 will suffer from fractures due to low density bone. The European Commission believes nanotechnology could help address these problems and has made the design and control of biomaterial at the nano-metre scale a strategic research priority.

One of the projects to benefit from this focus is the 'Electrically modified biomaterials surface' (Bioelectricsurface) project, whose team has been working with the aim of decreasing patients' trauma and the risk of death through a detailed understanding of nano-scale interactions of biological systems with biomaterials' surfaces. During the last year, the researchers have developed methods for electrical modifications of three leading biomaterials, namely hydroxyapatite (HA), polyurethane (PU) and titanium dioxide (TiO2).

They have also studied biological interactions with these electrically modified surfaces, noting that preliminary studies showed a selective response of biological species, such as antibodies and cells, towards charged surfaces.

The team is now developing techniques to further enhance this knowledge of and to exploit it in biomedical devices. The goal is to develop novel therapeutic devices in four specific biomedical applications: cardiovascular stents, urological stents, orthopaedic implants and grafts, and anti-microbial fabrics.

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