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smartCC SIGNED

Designing novel smart sensor interfaces based on a biologically abundant peptide motif: coiled-coils

Total Cost €

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EC-Contrib. €

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Partnership

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Project "smartCC" data sheet

The following table provides information about the project.

Coordinator
MAX PLANCK INSTITUT FUR EISENFORSCHUNG GMBH 

Organization address
address: MAX PLANCK STRASSE 1
city: DUSSELDORF
postcode: 40237
website: http://www.mpie.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://www.mpie.de
 Total cost 159˙460 €
 EC max contribution 159˙460 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-06-01   to  2019-09-15

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    MAX PLANCK INSTITUT FUR EISENFORSCHUNG GMBH DE (DUSSELDORF) coordinator 159˙460.00

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 Project objective

Smart interfaces alter their properties in response to an external trigger. Such devices open exciting opportunities for novel technologies with manifold applications. Electrical fields pose easily controllable triggers for smart interfaces and even allow a precise 'digital' switching between 'on' and 'off' states. The research project ‘smartCC’ will employ a biologically abundant class of biomacromolecules – coiled-coil peptides – to prepare smart selective interfaces, whose ability to specifically bind targets can be switched reversibly. Moreover, the produced interface will constitute a highly sensitive sensor by application of the attenuated total reflection infrared reflection technique. The variability of coiled-coils, employed in numerous biological systems, will also extend the potential application bandwidth of smart interfaces significantly. Molecular details of the switching and binding behaviour of the coiled-coils at the interface will be studied to test the feasibility of the envisioned working principle. Furthermore, the novel devices will be tested for an application with industrial relevance. To reach the goals of ‘smartCC’ a highly interdisciplinary approach is chosen that includes cooperation between three academic and one non-academic European partners. Thus, the implementation of this project will support bringing an emerging technology towards an economical benefit, foster intra European collaborations and mobility as well as strengthen Europe’s scientific sector.

 Publications

year authors and title journal last update
List of publications.
2019 Aimee L. Boyle, Martin Rabe, Niek S. A. Crone, Guto G. Rhys, Nicolas Soler, Patrick Voskamp, Navraj S. Pannu, Alexander Kros
Selective coordination of three transition metal ions within a coiled-coil peptide scaffold
published pages: 7456-7465, ISSN: 2041-6520, DOI: 10.1039/c9sc01165j
Chemical Science 10/31 2020-04-06
2018 Fang Niu, Martin Rabe, Simantini Nayak, Andreas Erbe
Vibrational spectroscopic study of pH dependent solvation at a Ge(100)-water interface during an electrode potential triggered surface termination transition
published pages: 222824, ISSN: 0021-9606, DOI: 10.1063/1.5018796
The Journal of Chemical Physics 148/22 2020-04-06
2019 Geert A. Daudey, Christian Schwieger, Martin Rabe, Alexander Kros
Influence of Membrane–Fusogen Distance on the Secondary Structure of Fusogenic Coiled Coil Peptides
published pages: 5501-5508, ISSN: 0743-7463, DOI: 10.1021/acs.langmuir.8b04195
Langmuir 35/16 2020-04-06

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