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KidsAP SIGNED

The artificial pancreas in children aged 1 to 7 years with type 1 diabetes

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

KidsAP project word cloud

Explore the words cloud of the KidsAP project. It provides you a very rough idea of what is the project "KidsAP" about.

sensor predictive transform complication pancreas supporting eye treatment last insulin longest administration care algorithm outcomes episodes individualised chronic artificial therapeutic acceptable heart therapy daily months children type biomedical pilot understand reimbursement improvements pump childern complications aged diabetes spearhead life amounts missing effectiveness promises modality interviews evaluates 24 levels kidney living poor optimise national international live glucose guidelines 94 leads n influence young clinical rapid combining quality psychosocial dependency 12 time health brain 47 below diseases disease half free delivering structured threatening semi

Project "KidsAP" data sheet

The following table provides information about the project.

Coordinator	THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE Organization address address: TRINITY LANE THE OLD SCHOOLS city: CAMBRIDGE postcode: CB2 1TN website: www.cam.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://kidsap.mrl.ims.cam.ac.uk/
Total cost	4˙952˙796 €
EC max contribution	4˙637˙477 € (94%)
Programme	1. H2020-EU.3.1.3. (Treating and managing disease)
Code Call	H2020-SC1-2016-RTD
Funding Scheme	RIA
Starting year	2017
Duration (year-month-day)	from 2017-01-01 to 2020-06-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE Organization address address: TRINITY LANE THE OLD SCHOOLS city: CAMBRIDGE postcode: CB2 1TN website: www.cam.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (CAMBRIDGE)	coordinator	1˙567˙828.00
2	MEDIZINISCHE UNIVERSITAT GRAZ MEDIZINISCHE UNIVERSITAT GRAZ Organization address address: AUENBRUGGERPLATZ 2 city: GRAZ postcode: 8036 website: http://www.medunigraz.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (GRAZ)	participant	441˙191.00
3	MEDIZINISCHE UNIVERSITAET WIEN MEDIZINISCHE UNIVERSITAET WIEN Organization address address: SPITALGASSE 23 city: WIEN postcode: 1090 website: www.meduniwien.ac.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (WIEN)	participant	430˙275.00
4	CENTRE HOSPITALIER DE LUXEMBOURG CENTRE HOSPITALIER DE LUXEMBOURG Organization address address: RUE NICOLAS ERNEST BARBLE 4 city: LUXEMBOURG postcode: 1210 website: www.chl.lu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	LU (LUXEMBOURG)	participant	399˙025.00
5	MEDIZINISCHE UNIVERSITAT INNSBRUCK MEDIZINISCHE UNIVERSITAT INNSBRUCK Organization address address: CHRISTOPH PROBST PLATZ 1 city: INNSBRUCK postcode: 6020 website: www.i-med.ac.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (INNSBRUCK)	participant	399˙025.00
6	THE LEEDS TEACHING HOSPITALS NATIONAL HEALTH SERVICE TRUST THE LEEDS TEACHING HOSPITALS NATIONAL HEALTH SERVICE TRUST Organization address address: ST JAMES'S UNIVERSITY HOSPITAL, BECKETT STREET city: LEEDS postcode: LS9 7TF website: www.leedsteachinghospitals.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LEEDS)	participant	399˙025.00
7	UNIVERSITAET LEIPZIG UNIVERSITAET LEIPZIG Organization address address: RITTERSTRASSE 26 city: LEIPZIG postcode: 4109 website: www.uni-Ieipzig.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (LEIPZIG)	participant	399˙025.00
8	THE UNIVERSITY OF EDINBURGH THE UNIVERSITY OF EDINBURGH Organization address address: OLD COLLEGE, SOUTH BRIDGE city: EDINBURGH postcode: EH8 9YL website: www.ed.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (EDINBURGH)	participant	325˙458.00
9	DIASEND AB DIASEND AB Organization address address: DATAVAGEN 14A city: ASKIM postcode: 43632 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (ASKIM)	participant	182˙843.00
10	HEVA HEOR HEVA HEOR Organization address address: 186 AVENUE THIERS LE 6EME SENS city: LYON postcode: 69006 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (LYON)	participant	93˙780.00
11	JAEB CENTER FOR HEALTH RESEARCH FOUNDATION INC JAEB CENTER FOR HEALTH RESEARCH FOUNDATION INC Organization address address: 15310 AMBERLY DRIVE SUITE 350 city: TAMPA postcode: 33647 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (TAMPA)	participant	0.00

Map

Project objective

TYPE 1 DIABETES is one of the most COMMON CHRONIC diseases in children with a RAPID increase in number of cases particularly in young children. Type 1 diabetes is associated with LIFE-LONG dependency on insulin administration. POOR glucose control leads to diabetes COMPLICATIONS, e.g. eye, heart, kidney disease, including BRAIN changes in young children. Episodes of VERY LOW glucose levels may be life threatening and are a major complication.

The ARTIFICIAL PANCREAS addresses the problem of LOW and HIGH glucose levels by delivering insulin BELOW and ABOVE pre-set amounts according to real-time sensor GLUCOSE levels, combining glucose SENSOR, insulin PUMP, and CONTROL ALGORITHM. The Artificial pancreas promises to TRANSFORM management of type 1 diabetes but EVIDENCE supporting its use during FREE LIVING in YOUNG CHILDREN is MISSING.

The project evaluates the biomedical, psychosocial, and cost effectiveness of NOVEL INDIVIDUALISED artificial pancreas in young children aged 1 to 7 years with type 1 diabetes. Following a PILOT (n=24), in the MAIN study (n=94) half of the participants (n=47) will be treated over 12 MONTHS by the ARTIFICIAL PANCREAS and the other half (n=47) by STATE-OF-THE-ART PREDICTIVE LOW GLUCOSE MANAGEMENT insulin pump therapy. Each treatment will last ONE YEAR. QUALITY OF LIFE will be assessed and semi-structured INTERVIEWS conducted to understand the impact on daily life. HEALTH TECHNOLOGY ASSESSMENT will support reimbursement.

The project will OPTIMISE artificial pancreas and SPEARHEAD SYSTEM-WIDE improvements in health care quality and health outcomes in YOUNG CHILDERN with TYPE 1 DIABETES who live with the disease LONGEST. By IMPROVING THERAPEUTIC OUTCOMES, the project will CHANGE clinical practice and INFLUENCE national and international treatment guidelines making the artificial pancreas WIDELY ACCEPTABLE as the state-of-art treatment modality in young children.

Deliverables

List of deliverables.
Public project website online	Websites, patent fillings, videos etc.	2020-04-08 14:17:31

Take a look to the deliverables list in detail: detailed list of KidsAP deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Martin Tauschmann, Janet M. Allen, Katrin Nagl, Maria Fritsch, James Yong, Emily Metcalfe, Dominique Schaeffer, Muriel Fichelle, Ulrike Schierloh, Alena G. Thiele, Daniela Abt, Harald Kojzar, Julia K. Mader, Sonja Slegtenhorst, Nicole Barber, Malgorzata E. Wilinska, Charlotte Boughton, Gianluca Musolino, Judy Sibayan, Nathan Cohen, Craig Kollman, Sabine E. Hofer, Elke FrÃ¶hlich-Reiterer, Thomas M. Home Use of Day-and-Night Hybrid Closed-Loop Insulin Delivery in Very Young Children: A Multicenter, 3-Week, Randomized Trial published pages: 594-600, ISSN: 0149-5992, DOI: 10.2337/dc18-1881	Diabetes Care 42/4	2020-04-08
2019	Klemen Dovc, Charlotte Boughton, Martin Tauschmann, Hood Thabit, Lia Bally, Janet M. Allen, Carlo L. Acerini, Sabine Arnolds, Carine de Beaufort, Richard M. Bergenstal, Fiona Campbell, Amy Criego, David B. Dunger, Daniella Elleri, Mark L. Evans, Elke FrÃ¶hlich-Reiterer, Sabine Hofer, Thomas Kapellen, Lalantha Leelarathna, Thomas R. Pieber, Birgit Rami-Merhar, Viral N. Shah, Judy Sibayan, Malgorzat Young Children Have Higher Variability of Insulin Requirements: Observations During Hybrid Closed-Loop Insulin Delivery published pages: 1344-1347, ISSN: 0149-5992, DOI: 10.2337/dc18-2625	Diabetes Care 42/7	2020-04-08
2019	Gianluca Musolino, Klemen Dovc, Charlotte K. Boughton, Martin Tauschmann, Janet M. Allen, Katrin Nagl, Maria Fritsch, James Yong, Emily Metcalfe, Dominique Schaeffer, Muriel Fichelle, Ulrike Schierloh, Alena G. Thiele, Daniela Abt, Harald Kojzar, Julia K. Mader, Sonja Slegtenhorst, Nicole Ashcroft, Malgorzata E. Wilinska, Judy Sibayan, Nathan Cohen, Craig Kollman, Sabine E. Hofer, Elke FrÃ¶hlich Reduced burden of diabetes and improved quality of life: Experiences from unrestricted dayâ€andâ€night hybrid closedâ€loop use in very young children with type 1 diabetes published pages: , ISSN: 1399-543X, DOI: 10.1111/pedi.12872	Pediatric Diabetes	2020-04-08

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The information about "KIDSAP" are provided by the European Opendata Portal: CORDIS opendata.