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BLOC SIGNED

BENCHTOP NMR FOR LAB-ON-CHIP

Total Cost €

EC-Contrib. €

Partnership

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BLOC project word cloud

Explore the words cloud of the BLOC project. It provides you a very rough idea of what is the project "BLOC" about.

miniaturise dnp polarisation islets fabricate organ liver tissues industry hardware spectroscopy disease nuclear software spheroids mr enabled screening pharmaceutical device biomimetic monitor experimental sensing microfluidic models dynamic multiple tissue vitro capability drug diseases magnetic create imaging pancreatic revolutionise predictive resonance metabolic ooc proof discovery chip candidates degree fabrication organs variables biologically content

Project "BLOC" data sheet

The following table provides information about the project.

Coordinator	FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA Organization address address: CARRER BALDIRI REIXAC PLANTA 2A 10-12 city: BARCELONA postcode: 8028 website: http://www.ibecbarcelona.eu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Total cost	2˙911˙780 €
EC max contribution	2˙911˙780 € (100%)
Programme	1. H2020-EU.1.2.1. (FET Open)
Code Call	H2020-FETOPEN-2018-2019-2020-01
Funding Scheme	RIA
Starting year	2020
Duration (year-month-day)	from 2020-01-01 to 2022-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA Organization address address: CARRER BALDIRI REIXAC PLANTA 2A 10-12 city: BARCELONA postcode: 8028 website: http://www.ibecbarcelona.eu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	coordinator	985˙808.00
2	MULTIWAVE TECHNOLOGIES AG MULTIWAVE TECHNOLOGIES AG Organization address address: 3 CHEMIN DU PRE FLEURI city: GENEVA postcode: 1228 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (GENEVA)	participant	901˙646.00
3	OXFORD INSTRUMENTS INDUSTRIAL PRODUCTS LIMITED OXFORD INSTRUMENTS INDUSTRIAL PRODUCTS LIMITED Organization address address: TUBNEY WOODS city: ABINGDON postcode: OX13 5QX website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (ABINGDON)	participant	575˙000.00
4	CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER Organization address address: CALLE ROSSELLO 149 PUERTA BJS city: BARCELONA postcode: 8036 website: http://www.idibaps.org/en_index.html contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	participant	449˙325.00

Map

Project objective

Organ-on-a-chip (OOC) devices offer new approaches to metabolic disease modelling and drug discovery by providing biologically relevant models of tissues and organs in vitro integrated with sensing technology. As such, OOC devices have the potential to revolutionise the pharmaceutical industry by enabling reliable and high predictive in vitro testing of drug candidates. The capability to miniaturise microfluidic systems and advanced tissue fabrication procedures have enabled researchers to create multiple tissues on a chip with a high degree of control over experimental variables for high-content screening applications. The objective of this project is to develop a new technology based on magnetic resonance spectroscopy and imaging using dynamic nuclear polarisation (DNP-MR) integrated with OOC devices to monitor disease and evaluate drug response in OOC models. As a proof-of-concept, this project will fabricate a biomimetic multi OOC integrated device composed of liver spheroids and pancreatic islets and develop the necessary DNP-MR hardware and software to study metabolic diseases and for future drug screening applications.

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The information about "BLOC" are provided by the European Opendata Portal: CORDIS opendata.