NANODNASEQUENCING
NanoTools for Ultra Fast DNA Sequencing
| Coordinatore | INSTITUT ZA FIZIKU
Organization address
address: Pregrevica 118 contact info |
| Nazionalità Coordinatore | Serbia [RS] |
| Sito del progetto | http://www.nanoDNAsequencing.org |
| Totale costo | 2˙861˙368 € |
| EC contributo | 2˙170˙925 € |
| Programma | FP7-NMP
Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies |
| Code Call | FP7-NMP-2007-SMALL-1 |
| Funding Scheme | CP-FP |
| Anno di inizio | 2008 |
| Periodo (anno-mese-giorno) | 2008-12-01 - 2011-11-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
INSTITUT ZA FIZIKU
Organization address
address: Pregrevica 118 contact info |
RS (BEOGRAD) | coordinator | 0.00 |
| 2 |
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Organization address
address: BATIMENT CE 3316 STATION 1 contact info |
CH (LAUSANNE) | participant | 0.00 |
| 3 |
Karlsruher Institut fuer Technologie
Organization address
address: Kaiserstrasse 12 contact info |
DE (Karlsruhe) | participant | 0.00 |
| 4 |
NUWAVE SYSTEM LTD
Organization address
address: PERCY STREET 5 OFFICE 4 contact info |
UK (LONDON) | participant | 0.00 |
| 5 |
THE HEBREW UNIVERSITY OF JERUSALEM.
Organization address
address: GIVAT RAM CAMPUS contact info |
IL (JERUSALEM) | participant | 0.00 |
| 6 |
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Organization address
address: College Green - contact info |
IE (DUBLIN) | participant | 0.00 |
| 7 |
UNIVERSITAET REGENSBURG
Organization address
address: UNIVERSITAETSSTRASSE 31 contact info |
DE (REGENSBURG) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
'The demand for a next-generation of technologies for DNA sequencing that will provide fast and affordable DNA decoding is pressing. Present bio-chemical schemes are time consuming and expensive, thus cheap and fast alternatives for DNA “reading” are of great need. This is now internationally recognized. For example, the US NIH recently awarded 40M$ in grants overpiloting projects to spur development of these innovative technologies. The goal of this project is to investigate a novel single-molecule DNA se-quencing nanotechnology protocol (gene sequencer) that has potential to sequence a molecule of genomic dimensions in hours without expensive and fault sensitive DNA copying steps and chemical reactions. The gene sequencer is based on the electrical characterization of individual nucleo-bases, while DNA passes through a nanopore with integrated nanotube side-electrodes. The research proposed here will provide a unique combina-tion of state of the art capabilities for cutting and usage of single wall carbon nanotubes as electrodes forming a lithographically fabricated “nanogap” with single-nanometer precision. In addition, the synergy of consortium resources for electrical characterization and leading theoretical skills for nanotransport will provide new solutions and information for an answer on the proof-of-principle question: is it possible to detect different types of DNA bases by their electrical properties? The overall objective of our collaborative research is to develop cheap and high-speed DNA sequencing technology. This will be achieved trough the following steps: 1. Fabrication of single wall carbon nanotube junction-gate for molecular recognition; 2. Exploring the interaction and conduction mechanisms between DNA and nanotube-electrode and DNA-nanopore; 3. Electrical characterization of the DNA nucleobases; 4. Development of model nano-electronic device for single-base DNA electrical characterization and decoding.'