MEIOSYS
Systematic analysis of factors controlling meiotic recombination in higher plants
| Coordinatore | THE UNIVERSITY OF BIRMINGHAM
Organization address
address: Edgbaston contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Totale costo | 6˙223˙215 € |
| EC contributo | 4˙499˙920 € |
| Programma | FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology |
| Code Call | FP7-KBBE-2007-2A |
| Funding Scheme | CP-IP |
| Anno di inizio | 2009 |
| Periodo (anno-mese-giorno) | 2009-07-01 - 2014-06-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
THE UNIVERSITY OF BIRMINGHAM
Organization address
address: Edgbaston contact info |
UK (BIRMINGHAM) | coordinator | 1˙243˙872.00 |
| 2 |
UNIVERSITAT WIEN
Organization address
address: UNIVERSITATSRING 1 contact info |
AT (WIEN) | participant | 676˙390.00 |
| 3 |
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE
Organization address
address: Rue De L'Universite 147 contact info |
FR (PARIS CEDEX 07) | participant | 571˙380.00 |
| 4 |
THE SCOTTISH CROP RESEARCH INSTITUTE
Organization address
address: "ERROL ROAD, INVERGOWRIE" contact info |
UK (DUNDEE) | participant | 455˙262.00 |
| 5 |
CONSIGLIO NAZIONALE DELLE RICERCHE
Organization address
address: Piazzale Aldo Moro 7 contact info |
IT (ROMA) | participant | 355˙716.00 |
| 6 |
UNIVERSIDAD COMPLUTENSE DE MADRID
Organization address
address: AVENIDA DE SENECA 2 contact info |
ES (MADRID) | participant | 325˙890.00 |
| 7 |
FORSCHUNGSINSTITUT FUER MOLEKULARE PATHOLOGIE Ges.m.b.H
Organization address
address: Dr. Bohr-Gasse 7 contact info |
AT (VIENNA) | participant | 311˙202.00 |
| 8 |
STICHTING KATHOLIEKE UNIVERSITEIT
Organization address
address: GEERT GROOTEPLEIN NOORD 9 contact info |
NL (NIJMEGEN) | participant | 306˙480.00 |
| 9 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Organization address
address: Rue Michel -Ange 3 contact info |
FR (PARIS) | participant | 253˙728.00 |
| 10 |
THE JAMES HUTTON INSTITUTE
Organization address
address: ERROL ROAD INVERGOWRIE contact info |
UK (DUNDEE) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
'Meiotic recombination has underpinned plant breeding for the generation of new traits of agronomic, environmental and economic importance, although we still have little understanding of the controlling mechanisms involved in this process. We will combine approaches in genomics and systems biology to obtain a detailed understanding of the factors that control recombination and will provide a basis for the development of strategies to modify recombination in a variety of crop species.'
Introduzione (Teaser)
As the world population continues to grow, it becomes even more essential that there are enough crops to maintain the food supply. In an EU-funded project, scientists are manipulating the meiotic process in three crops to explore how genomics can help maintain food security.
Descrizione progetto (Article)
Meiosis is a process of cell division used by both plants and animals to produce gametes (sperm and eggs) for reproduction. Not only does the process ensure that the correct number of chromosomes are passed on, it also mixes the genes from previous generations to create genetic variation within a species.
This project, 'Systematic analysis of factors controlling meiotic recombination in higher plants' (MEIOSYS) changed events in meiosis in certain plants to create greater genetic variety, increase food production, and ensure food security.
Using genetics and bioinformatics, scientists focused on the plants Arabidopsis, brassicas, and the cereal crop barley. During the first phase of the project, scientists set up a database to share data on plant experiments.
With the goal of identifying genes controlling crossover frequency, investigators then used the gene AtFANCM1, which had shown promise as a crossover regulator, to study the barley plant. This work led to the discovery of FANCM helicase, the first gene that may alter recombination patterns. Scientists are currently generating more plants to monitor these patterns. To date, three additional genes have been discovered.
The next phase of the project involves transferring knowledge of meiosis to crop species. Using barley and brassicas, scientists targeted the SPO11 gene to monitor recombination events at specific genomic locations.
Today, plants are at the heart of the European food industry. Although intensive breeding has boosted plants' yield, quality, and resistance to stress, current predictions suggest that over the next 50 years, population growth and climate changes will result in the need for even greater quantities of food By applying genomics and systems biology to food production, scientists hope to maximise genetic variability, ensuring high-quality food for the 21st century.