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APRES

The appropriateness of prescribing antibiotics in primary health care in Europe with respect to antibiotic resistance

Coordinatore	STICHTING NEDERLANDS INSTITUUT VOOR ONDERZOEK VAN DE GEZONDHEIDSZORG Organization address address: OTTERSTRAAT 118-124 city: UTRECHT postcode: 3500 BN contact info Titolo: Mr. Nome: Robert Cognome: Dessing Email: send email Telefono: +31 302 729823 Fax: +31 302 729 729
Nazionalità Coordinatore	Netherlands [NL]
Totale costo	3˙632˙363 €
EC contributo	2˙809˙511 €
Programma	FP7-HEALTH Specific Programme "Cooperation": Health
Code Call	FP7-HEALTH-2007-B
Funding Scheme	CP-FP
Anno di inizio	2009
Periodo (anno-mese-giorno)	2009-10-01 - 2014-03-31

Partecipanti

#	participant	country	role	EC contrib. [€]
1	STICHTING NEDERLANDS INSTITUUT VOOR ONDERZOEK VAN DE GEZONDHEIDSZORG Organization address address: OTTERSTRAAT 118-124 city: UTRECHT postcode: 3500 BN contact info Titolo: Mr. Nome: Robert Cognome: Dessing Email: send email Telefono: +31 302 729823 Fax: +31 302 729 729	NL (UTRECHT)	coordinator	882˙244.44
2	UNIVERSITEIT MAASTRICHT Organization address address: Minderbroedersberg 4-6 city: MAASTRICHT postcode: 6200 MD contact info Titolo: Mr. Nome: Erie Cognome: Van Den Heuvel Email: send email Telefono: 31433882822	NL (MAASTRICHT)	participant	701˙420.00
3	UNIVERSITEIT ANTWERPEN Organization address address: PRINSSTRAAT 13 city: ANTWERPEN postcode: 2000 contact info Titolo: Ms. Nome: Anne Cognome: Adams Email: send email Telefono: 3232653028 Fax: 3232653011	BE (ANTWERPEN)	participant	300˙520.00
4	THE UNIVERSITY OF NOTTINGHAM Organization address address: University Park city: NOTTINGHAM postcode: NG7 2RD contact info Titolo: Mr. Nome: Paul Cognome: Cartledge Email: send email Telefono: +44 115 9515 679 Fax: +44 115 9513 633	UK (NOTTINGHAM)	participant	139˙480.94
5	"FUNDACIO JORDI GOL I GURINA, FUNDACIO PRIVADA PER A LA RECERCA A L'ATENCIO PRIMARIA DE SALUT" Organization address address: Gran Via de les Corts Catalanes 587 city: Barcelona postcode: 8007 contact info Nome: José Maria Cognome: Gállego Email: send email Telefono: 34934824279 Fax: 34934824174	ES (Barcelona)	participant	110˙776.00
6	"SVEUCILISTE U ZAGREBU, MEDICINSKI FAKULTET" Organization address address: SALATA 3 city: ZAGREB postcode: 10000 contact info Titolo: Ms. Nome: Smiljka Cognome: Viki?-Topi? Email: send email Telefono: +385 1 4566 972 Fax: +385 1 4566 724	HR (ZAGREB)	participant	94˙960.00
7	JONKOPINGS LAN	SE	participant	94˙315.60
8	SOCIETE FRANCAISE DE MEDECINE GENERALE Organization address address: avenue de Verdun 141 city: ISSY LES MOULINEAUX postcode: 92130 contact info Titolo: Dr. Nome: Gilles Cognome: Hebrecht Email: send email Telefono: +331419070 81 Fax: 33141900782	FR (ISSY LES MOULINEAUX)	participant	90˙160.00
9	DEBRECENI EGYETEM Organization address address: EGYETEM TER 1 city: DEBRECEN postcode: 4032 contact info Titolo: Mr. Nome: Gábor Cognome: Kecskés Email: send email Telefono: +36 52 410 960 Fax: +36 52 44 22 05	HU (DEBRECEN)	participant	87˙400.00
10	MEDIZINISCHE UNIVERSITAET WIEN Organization address address: SPITALGASSE 23 city: WIEN postcode: 1090 contact info Titolo: Prof. Nome: Manfred Cognome: Maier Email: send email Telefono: 431428000000 Fax: 431428000000	AT (WIEN)	participant	81˙034.00
11	KATHOLIEKE UNIVERSITEIT LEUVEN Organization address address: Oude Markt 13 city: LEUVEN postcode: 3000 contact info Titolo: Ms. Nome: Elke Cognome: Lammertyn Email: send email Telefono: +32 16 320621 Fax: +32 16 326515	BE (LEUVEN)	participant	79˙384.00
12	Royal College of General Practitioners Organization address address: "Princes Gate, Hyde Park 14" city: London postcode: SW7 1PU contact info Titolo: Ms. Nome: Ruth Cognome: Palmer Email: send email Telefono: +44 2031887426	UK (London)	participant	77˙520.00
13	ALLGEMEIN OFFENTLICHES KRANKENHAUS DER ELISABETHINEN Organization address address: FADINGERSTRASSE 1 city: LINZ postcode: 4010 contact info Titolo: Dr. Nome: Petra Cognome: Apfalter Email: send email Telefono: +43 732 7676 3693 Fax: +43 732 7676 3686	AT (LINZ)	participant	35˙736.00
14	NORTH BRISTOL NATIONAL HEALTH SERVICE TRUST Organization address address: BECKSPOOL ROAD FRENCHAY HOSPITAL . city: BRISTOL postcode: BS16 1JE contact info Titolo: Dr. Nome: Andrew Cognome: Lovering Email: send email Telefono: +44 117 3234311 Fax: +44 117 323 6192	UK (BRISTOL)	participant	34˙560.00

Mappa

Word cloud

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bacteria care appropriateness evidence guidelines primary antibiotics circulating apres consumption community pattern data countries prescribed patterns samples antibiotic patients practices wp prescribing health resistance hospitalized outpatient nine pathogens

Obiettivo del progetto (Objective)

'The APRES project aims at providing information and recommendations on the appropriateness of prescribing antibiotics in primary care. The appropriateness of prescribing antibiotics is the extent to which the pattern of prescribed antibiotics is congruent with the antibiotic resistance pattern of bacteria. More than 90% of antibiotics in Europe is prescribed to non-hospitalized patients, but existing information on the antibiotic resistance pattern is exclusively based on samples from hospitalized patients. Guidelines for prescribing antibiotics to outpatients cannot be based on empirical evidence about antibiotic resistance of bacteria circulating in the community because this evidence is lacking. The APRES project contains 4 work packages. WP1 includes a) a systematic review on the relationship between outpatient consumption of antibiotics and patterns of antibiotic resistance of pathogens circulating in the community; b) the establishment of a database of information sources and databases in nine European countries on outpatient consumption of antibiotics and antibiotic resistance patterns of pathogens circulating in the community. In WP2 the antibiotic resistance pattern of S. aureus and S. pneumoniae will be established in nine European countries, based on samples from healthy persons consulting in primary care practices participating in nationally representative networks. In WP3 we will establish the 5-year pattern of prescribed antibiotics the same practices and its variation between nine European countries. The data will be retrieved from electronic medical records in the same primary care practices. WP4 includes the integrative analyses by linking the antibiotic prescribing data with the antibiotic resistance patterns obtained in the same practices to establish the appropriateness of prescribing antibiotics. On the basis of these results, country specific guidelines will be formulated for appropriate prescribing of antibiotics.'

Introduzione (Teaser)

Antibiotic resistance is a growing public health concern as effective therapy is hampered, leading to higher health care expenses, morbidity and sometimes mortality. Studies worldwide have shown that higher antibiotic consumption is linked to increased antibiotic resistance.