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CCMI-ARDS

Medically Licensed Mesenchymal Stem Cells for Acute Respiratory Distress Syndrome.

Total Cost €

EC-Contrib. €

Partnership

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CCMI-ARDS project word cloud

Explore the words cloud of the CCMI-ARDS project. It provides you a very rough idea of what is the project "CCMI-ARDS" about.

respiratory cell distress thousands syndrome kills shown culture ards human exhibit hundreds transport hmsc efforts thawed starter therapeutic deaths demonstration manufactured mesenchymal stem bedside 40 beneficial sufferers nfkb erc passaged worldwide site strategies cells administered successfully allogeneically annually clinical cryofrozen acute ing examine patients clinic preclinical patient catastrophic galway vili devastating sourced facility near grant ccmi mscs despite therapy nui intensive disease decades therapies models

Project "CCMI-ARDS" data sheet

The following table provides information about the project.

Coordinator	NATIONAL UNIVERSITY OF IRELAND GALWAY Organization address address: UNIVERSITY ROAD city: Galway postcode: H91 website: www.nuigalway.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Ireland [IE]
Total cost	149˙101 €
EC max contribution	149˙101 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2014-PoC
Funding Scheme	ERC-POC
Starting year	2015
Duration (year-month-day)	from 2015-01-01 to 2015-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	NATIONAL UNIVERSITY OF IRELAND GALWAY NATIONAL UNIVERSITY OF IRELAND GALWAY Organization address address: UNIVERSITY ROAD city: Galway postcode: H91 website: www.nuigalway.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (Galway)	coordinator	149˙101.00

Map

Project objective

Acute Respiratory Distress Syndrome (ARDS) is a devastating condition, which kills 40% of sufferers, resulting in hundreds of thousands of deaths worldwide annually. Despite decades of intensive research efforts, there are no clinical therapeutic strategies available for this catastrophic condition. In our ERC Starter Grant, HA-NFkB-VILI, we have shown Mesenchymal Stem Cells (MSCs) to be beneficial in several relevant preclinical ARDS models. However, for cell therapies to be successfully used in the clinic, they will need to be sourced allogeneically, culture passaged and cryofrozen for transport to the clinical site, where they can then thawed near the bedside and administered to the patient with ARDS. This project will therefore examine the potential of cryofrozen human MSCs, manufactured at the CCMI cell therapy facility at NUI Galway, in relevant models of ARDS. A demonstration that the cryofrozen CCMI-hMSC exhibit therapeutic potential would be a major step towards the clinical testing of these cells in patients with this devastating disease.

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The information about "CCMI-ARDS" are provided by the European Opendata Portal: CORDIS opendata.