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JUNO SIGNED

Joint Volumetric Reconstruction and Automated Analysis of the Fetal Heart from Cardiovascular Magnetic Resonance Images

Total Cost €

0

EC-Contrib. €

0

Partnership

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 Outcomes and results

 JUNO project word cloud

Explore the words cloud of the JUNO project. It provides you a very rough idea of what is the project "JUNO" about.

ejection    goals    qualitative    segmentation    therapy    magnetic    volume    quantitative    causes    volumetric    intervention    fraction    clinical    resolution    iugr    single    stroke    remodeling    extraction    mortality    noninvasive    dependent    contours    deformable    potentially    juno    accurate    atlases    tool    operator    congenital    healthy    limited    diagnosis    first    fact    resonance    limitations    time    acquisitions    outcomes    induces    made    advancements    registration    models    evaluation    recent    intrauterine    worldwide    cmr    functional    planning    automated    diseases    thanks    slice    acquisition    methodology    fundamental    identification    unfortunately    structural    datasets    image    tackling    feasibility    static    dynamic    these    detection    restriction    acquired    techniques    boundaries    groundbreaking    reconstruction    postnatal    imaging    perinatal    cardiovascular    chds    heart    utero    super    vivo    vessels    infant    innovative    ventricular    fetal    structures    fetuses    capability    administration   

Project "JUNO" data sheet

The following table provides information about the project.

Coordinator		 IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE 

Organization address
address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
city: LONDON
postcode: SW7 2AZ
website: http://www.imperial.ac.uk/

contact info
title: n.a.
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surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
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 Coordinator Country United Kingdom [UK]
 Project website https://www.doc.ic.ac.uk/
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-11-16   to  2017-11-15

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE UK (LONDON) coordinator 183˙454.00

Map

 Project objective

Recent advancements in cardiovascular magnetic resonance (CMR) have finally made possible static and dynamic in-vivo imaging of the fetal heart. This new capability has the potential to provide a fundamental new tool for structural and functional assessment of the fetal cardiovascular system, with groundbreaking clinical consequences. In fact, congenital heart diseases (CHDs) and intrauterine growth restriction (IUGR, which induces cardiovascular remodeling) are among the leading causes of infant mortality worldwide. Fetal CMR imaging may potentially allow more accurate diagnosis of these conditions, and thus improve postnatal outcomes thanks to better in-utero therapy administration, delivery and perinatal intervention planning. Unfortunately, fetal CMR is currently limited to the acquisition of a single slice in time, allowing only qualitative and operator-dependent evaluation of the fetal heart. The JUNO project aims at improving the present capabilities of fetal CMR by tackling its limitations with an image processing approach. The specific goals are (1) development of a method for super resolution volumetric reconstruction of the fetal heart, using image registration techniques applied to a set of single-slice acquisitions; (2) development of automated segmentation methods, based on deformable models and atlases, for the identification of structures such as ventricular contours and main vessels’ boundaries; (3) extraction of quantitative functional parameters (e.g. stroke volume and ejection fraction) from datasets acquired from healthy, CHDs- and IUGR-affected fetuses, to test the feasibility of objective detection of these conditions. By achieving these goals, JUNO will provide an innovative set of methods allowing for the first time quantitative, noninvasive, functional assessment of the fetal cardiovascular system, and thus address a long standing clinical need for such methodology.

 Publications

year authors and title journal last update
List of publications.
2017 W Bai, O Oktay, M Sinclair, H Suzuki, M Rajchl, G Tarroni, B Glocker, A King, PM Matthews, D Rueckert
Semi-supervised Learning for Network-Based Cardiac MR Image Segmentation
published pages: 253-260, ISSN: , DOI: 		Medical Image Computing and Computer-Assisted Intervention (MICCAI), LNCS 10434 2019-06-13
2017 G Tarroni, O Oktay, A Schuh, W Bai, A de Marvao, D O\'Regan, S Cook, D Rueckert
Slice Realignment for Motion-Corrupted Stacks of Short-Axis Cine Cardiac MR Images based on 3D Probabilistic Edge Maps
published pages: , ISSN: , DOI: 		Proc. Intl. Soc. Mag. Reson. Med. 25 2019-06-13
2017 G Tarroni, O Oktay, W Bai, A Schuh, H Suzuki, J Passerat-Palmbach, B Glocker, A de Marvao, D O\'Regan, S Cook, D Rueckert
Learning-Based Heart Coverage Estimation for Short-Axis Cine Cardiac MR Images
published pages: 73-82, ISSN: , DOI: 		Functional Imaging and Modelling of the Heart (FIMH), LNCS 10263 2019-06-13

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