Explore the words cloud of the Amine-FUNC project. It provides you a very rough idea of what is the project "Amine-FUNC" about.
The following table provides information about the project.
Coordinator |
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
Organization address contact info |
Coordinator Country | United Kingdom [UK] |
Project website | http://www-gaunt.ch.cam.ac.uk |
Total cost | 195˙454 € |
EC max contribution | 195˙454 € (100%) |
Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
Code Call | H2020-MSCA-IF-2014 |
Funding Scheme | MSCA-IF-EF-ST |
Starting year | 2015 |
Duration (year-month-day) | from 2015-04-01 to 2017-03-31 |
Take a look of project's partnership.
# | ||||
---|---|---|---|---|
1 | THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE | UK (CAMBRIDGE) | coordinator | 195˙454.00 |
The development of new chemical transformations based on catalytic functionalization of unactivated C-H bonds has the potential to simplify the synthesis of complex molecules dramatically. Although some progress have been achieved in this emerging area, the selective transformation of aliphatic C-H bonds is still a challenge. This proposal aims to develop a new platform for the direct activation of unactivated sp3 C-H bonds of aliphatic amines and to apply this novel C(sp3)-H functionalization technology to synthesize diverse amine compounds. A key novel concept of this project is to use an unprotected aliphatic secondary amine as a native directing group, through a remarkable 4-membered-ring cyclometallation pathway. The goals of this proposal include: (I) developing unprecedented diverse C(sp3)-H functionalization of amine technology, accessing diverse functionalized amine compounds, (II) developing novel Pd-catalyzed enantioselective C-H functionalization methods to make enantioenriched chiral molecules, (III) application of this novel C(sp3)-H functionalization technology to make a library of diverse functionalized Salbutamol and Bupropion analogues, and screen them for biological and medicinal activities.
year | authors and title | journal | last update |
---|---|---|---|
2015 |
Chuan He, Matthew J. Gaunt Ligand-Enabled Catalytic CH Arylation of Aliphatic Amines by a Four-Membered-Ring Cyclopalladation Pathway published pages: 15840-15844, ISSN: 1433-7851, DOI: 10.1002/anie.201508912 |
Angewandte Chemie International Edition 54/52 | 2019-07-23 |
2017 |
Chuan He, Matthew J. Gaunt Ligand-assisted palladium-catalyzed C–H alkenylation of aliphatic amines for the synthesis of functionalized pyrrolidines published pages: , ISSN: 2041-6520, DOI: 10.1039/C7SC00468K |
Chem. Sci. | 2019-07-23 |
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "AMINE-FUNC" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "AMINE-FUNC" are provided by the European Opendata Portal: CORDIS opendata.
Increases biomass production and soil organic carbon stocks with innovative cropping systems under climate change
Read MoreThe Comedy of Political Philosophy. Democratic Citizenship, Political Judgment, and Ideals in Political Practice.
Read MoreExploring thioalkynes potential in gold catalysis with a divergent reactivity manifold
Read More