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BluGram TERMINATED
Identification of genetic factors which determine host specificity in the wheat-powdery mildew pathosystem
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0BluGram project word cloud
Explore the words cloud of the BluGram project. It provides you a very rough idea of what is the project "BluGram" about.
strategies
hundreds
devastating
specificity
adaptive
events
combining
disease
mildew
tritici
evolution
strain
pathogen
differ
blumeria
obliagte
mechanisms
biotrophic
molecular
proteins
repetitive
sustainable
plant
strains
genetically
spectrum
manipulating
frequency
ago
specialized
sequencing
genome
powdery
introduction
broaden
caused
bread
wild
fungus
isolates
domesticated
pathology
breakpoints
effector
data
precise
species
disciplinary
unknown
virulence
arose
graminis
re
rational
genomics
recombination
indicated
cell
responsible
genes
mapping
cross
poorly
clusters
sp
population
grow
bgt
genetics
host
interactions
specialization
mapped
wheat
Project "BluGram" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSITY OF HAIFA
Organization address contact info |
| Coordinator Country | Israel [IL] |
| Total cost | 260˙674 € |
| EC max contribution | 260˙674 € (100%) |
| Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
| Code Call | H2020-MSCA-IF-2014 |
| Funding Scheme | MSCA-IF-GF |
| Starting year | 2015 |
| Duration (year-month-day) | from 2015-09-01 to 0000-00-00 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSITY OF HAIFA | IL (HAIFA) | coordinator | 260˙674.00 |
Map
Project objective
Powdery mildew caused by the fungus Blumeria graminis f.sp. tritici (Bgt) is a devastating disease of wheat with poorly understood plant-pathogen interactions. Sequencing of the Bgt genome indicated that hundreds of effector proteins are manipulating the plant cell and determining the virulence spectrum of a particular mildew strain. Bgt rapidly adapted to the introduction of the new host species bread wheat, which arose only 8,000-10,000 years ago. Bgt has since evolved into strains which are specialized on domesticated wheat and such which grow on wild wheat species. Genes responsible for the host specificity in an obliagte biotrophic fungus are unknown. To study the mechanisms of adaptive evolution in the highly repetitive Bgt genome, whole genome re-sequencing data of a mapping population derived from a cross between Bgt isolates that differ in their host specialization will be used to determine the frequency and distribution of recombination events and precise mapping of recombination breakpoints. Of particular interest is to study the impact of recombination on the clusters of effector genes. The factors that determine host specificity will be genetically mapped. This will allow conclusions on which and how many genes were responsible for the Bgt adaptation to the bread wheat host. The proposed research is taking a multi-disciplinary approach combining whole genome re-sequencing, classical genetics, molecular plant pathology and comparative genomics. This study will broaden our understanding of Bgt genome evolution and will help to design rational strategies for sustainable powdery mildew disease management.
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