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PERFORM SIGNED

Personalised Risk assessment in febrile illness to Optimise Real-life Management across the European Union

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

PERFORM project word cloud

Explore the words cloud of the PERFORM project. It provides you a very rough idea of what is the project "PERFORM" about.

cohorts invasive clinical bioinformatic phenotyping countries worldwide undergo trivial self characterised proteomic reflecting healthcare plan accurate sophisticated genomic phenotypic antibiotics recruited settings febrile fact prospective careful linking markers patients distinguishing diagnosis patient bacterial discriminators suffering unreliable care rolled providers building national grounds investigation data validate infections distinction health pilot infection resolving presumed hospitalization viral transcriptomic innumerable

Project "PERFORM" data sheet

The following table provides information about the project.

Coordinator	IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD city: LONDON postcode: SW7 2AZ website: http://www.imperial.ac.uk/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://www.perform2020.org
Total cost	18˙467˙697 €
EC max contribution	17˙997˙665 € (97%)
Programme	1. H2020-EU.3.1.6. (Health care provision and integrated care)
Code Call	H2020-PHC-2015-two-stage
Funding Scheme	RIA
Starting year	2016
Duration (year-month-day)	from 2016-01-01 to 2020-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD city: LONDON postcode: SW7 2AZ website: http://www.imperial.ac.uk/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	coordinator	6˙373˙692.00
2	STICHTING KATHOLIEKE UNIVERSITEIT STICHTING KATHOLIEKE UNIVERSITEIT Organization address address: GEERT GROOTEPLEIN NOORD 9 city: NIJMEGEN postcode: 6525 EZ website: www.radboudumc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (NIJMEGEN)	participant	1˙500˙000.00
3	LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER Organization address address: KEPPEL STREET city: LONDON postcode: WC1E 7HT website: http://www.lshtm.ac.uk/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	1˙385˙703.00
4	SERVIZO GALEGO DE SAUDE SERVIZO GALEGO DE SAUDE Organization address address: Edificio Administrativo San Lázaro city: Santiago de Compostela postcode: 15703 website: www.sergas.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (Santiago de Compostela)	participant	1˙004˙250.00
5	THE UNIVERSITY OF LIVERPOOL THE UNIVERSITY OF LIVERPOOL Organization address address: BROWNLOW HILL 765 FOUNDATION BUILDING city: LIVERPOOL postcode: L69 7ZX website: www.liverpool.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LIVERPOOL)	participant	989˙471.00
6	ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Organization address address: DR MOLEWATERPLEIN 40 city: ROTTERDAM postcode: 3015 GD website: www.erasmusmc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ROTTERDAM)	participant	970˙386.00
7	MEDIZINISCHE UNIVERSITAT GRAZ MEDIZINISCHE UNIVERSITAT GRAZ Organization address address: AUENBRUGGERPLATZ 2 city: GRAZ postcode: 8036 website: http://www.medunigraz.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (GRAZ)	participant	899˙500.00
8	THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Organization address address: WELLINGTON SQUARE UNIVERSITY OFFICES city: OXFORD postcode: OX1 2JD website: www.ox.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (OXFORD)	participant	799˙937.00
9	ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM Organization address address: MEIBERGDREEF 15 city: AMSTERDAM postcode: 1105AZ website: www.amc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	746˙450.00
10	UNIVERSITY OF NEWCASTLE UPON TYNE UNIVERSITY OF NEWCASTLE UPON TYNE Organization address address: KINGS GATE city: NEWCASTLE UPON TYNE postcode: NE1 7RU website: http://www.ncl.ac.uk/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (NEWCASTLE UPON TYNE)	participant	700˙743.00
11	UNITED KINGDOM RESEARCH AND INNOVATION UNITED KINGDOM RESEARCH AND INNOVATION Organization address address: POLARIS HOUSE NORTH STAR AVENUE city: SWINDON postcode: SN2 1FL website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (SWINDON)	participant	570˙000.00
12	BIOMERIEUX SA BIOMERIEUX SA Organization address address: Chemin de l'Orme city: Marcy l'Etoile postcode: 69280 website: www.biomerieux.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (Marcy l'Etoile)	participant	400˙100.00
13	MICROPATHOLOGY LIMITED MICROPATHOLOGY LIMITED Organization address address: SIR WILLIAM LYONS ROAD city: COVENTRY postcode: CV4 7EZ website: www.micropathology.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (COVENTRY)	participant	358˙681.00
14	ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON Organization address address: 6 CHRISTOU LADA STR city: ATHINA postcode: 10561 website: www.elke.uoa.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (ATHINA)	participant	350˙000.00
15	LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN Organization address address: GESCHWISTER SCHOLL PLATZ 1 city: MUENCHEN postcode: 80539 website: www.uni-muenchen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUENCHEN)	participant	350˙000.00
16	RIGAS STRADINA UNIVERSITATE RIGAS STRADINA UNIVERSITATE Organization address address: Dzirciema street 16 city: RIGA postcode: 1007 website: www.rsu.lv contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	LV (RIGA)	participant	299˙375.00
17	UNIVERZITETNI KLINICNI CENTER LJUBLJANA UNIVERZITETNI KLINICNI CENTER LJUBLJANA Organization address address: ZALOSKA CESTA 002 city: LJUBLJANA postcode: 1000 website: http://www.kclj.si/nuklearna contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SI (LJUBLJANA)	participant	299˙375.00
18	MEDICAL RESEARCH COUNCIL MEDICAL RESEARCH COUNCIL Organization address address: NORTH STAR AVENUE POLARIS HOUSE 2 FLOOR DAVID PHILLIPS BUILDING city: SWINDON postcode: SN2 1FL website: www.mrc.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (SWINDON)	participant	0.00
19	UNIVERSITAET BERN UNIVERSITAET BERN Organization address address: HOCHSCHULSTRASSE 6 city: BERN postcode: 3012 website: http://www.unibe.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (BERN)	participant	0.00

Map

Project objective

The management of febrile patients is one of the most common and important problems facing healthcare providers. Distinction between bacterial infections and trivial viral infection on clinical grounds is unreliable, and as a result innumerable patients worldwide undergo hospitalization, invasive investigation and are treated with antibiotics for presumed bacterial infection when, in fact, they are suffering from self-resolving viral infection. We aim to improve diagnosis and management of febrile patients, by application of sophisticated phenotypic, transcriptomic (genomic, proteomic) and bioinformatic approaches to well characterised large-scale, multi-national patient cohorts already recruited with EU funding. We will identify, and validate promising new discriminators of bacterial and viral infection including transcriptomic and clinical phenotypic markers. The most accurate markers distinguishing bacterial and viral infection will be evaluated in prospective cohorts of patients reflecting the different health care settings across European countries. By linking sophisticated new genomic and proteomic approaches to careful clinical phenotyping, and building on pilot data from our previous studies we will develop a comprehensive management plan for febrile patients which can be rolled out in healthcare systems across Europe.

Deliverables

List of deliverables.
Consent and Child Assent Forms	Documents, reports	2019-09-02 14:30:29
Project Handbook	Documents, reports	2019-09-02 14:30:29
Transcriptomic and proteomic signatures of bacterial and viral infections	Documents, reports	2019-09-02 14:30:29
PERFORM Website	Websites, patent fillings, videos etc.	2019-09-02 14:30:29
PERFORM Dissemination & Communnication Strategy	Documents, reports	2019-09-02 14:30:29
report on molecular diagnostics	Documents, reports	2019-09-02 14:30:29
Clinical Recruitment & Data Collection Documents	Documents, reports	2019-09-02 14:30:29
All Approvals Package	Documents, reports	2019-09-02 14:30:29
1st Annual Meeting Report	Documents, reports	2019-09-02 14:30:29
Tool-server Platforms	Documents, reports	2019-09-02 14:30:29
Provider, Parent and Costing Studies	Documents, reports	2019-09-02 14:30:29
Operational Database	Documents, reports	2019-09-02 14:30:29
Mid-Term Recruitment Report	Documents, reports	2019-09-02 14:30:29
Ethics Board Report (Preliminary)	Documents, reports	2019-09-02 14:30:29
2nd Annual Meeting Report	Documents, reports	2019-09-02 14:30:29
Ethics Review Report	Documents, reports	2019-09-02 14:30:29

Take a look to the deliverables list in detail: detailed list of PERFORM deliverables.

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The information about "PERFORM" are provided by the European Opendata Portal: CORDIS opendata.

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