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MOIPB TERMINATED

Multi-modal optical imaging platform for Biology

Total Cost €

EC-Contrib. €

Partnership

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MOIPB project word cloud

Explore the words cloud of the MOIPB project. It provides you a very rough idea of what is the project "MOIPB" about.

limited organism fcs tissue spatial platform coherence molecules mechanisms images incorporation spectroscopy cure clinical depletion tested imaging stimulated damage resolution links illumination samples reveal tissues microscopy modality basic create recovery with image concentration integrating laser investigation correlation engineering progress run scales optical sted adaptive functional molecular model structured 3d protein zebrafish emission biological oct optics disease wish sensitivity biology meet dynamics fluorescence technique tomography structural modal cell potentially

Project "MOIPB" data sheet

The following table provides information about the project.

Coordinator	THE UNIVERSITY OF MANCHESTER Organization address address: OXFORD ROAD city: MANCHESTER postcode: M13 9PL website: www.manchester.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Total cost	195˙454 €
EC max contribution	195˙454 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2015
Funding Scheme	MSCA-IF-EF-ST
Starting year	2017
Duration (year-month-day)	from 2017-01-01 to 2018-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE UNIVERSITY OF MANCHESTER THE UNIVERSITY OF MANCHESTER Organization address address: OXFORD ROAD city: MANCHESTER postcode: M13 9PL website: www.manchester.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (MANCHESTER)	coordinator	195˙454.00

Map

Project objective

With the progress of biological investigation, there comes a strong wish or need for imaging biological samples with multi-modality and on different scales. To meet this need, this project will develop a multi-modal 3D optical imaging platform that images on the multi-scale, from tissues to molecules, by integrating optical coherence tomography (OCT), stimulated emission depletion microscopy (STED), and fluorescence correlation spectroscopy (FCS). Incorporation of structured illumination, adaptive optics and focused engineering will improve spatial resolution, imaging depth, and molecular concentration sensitivity. The investigated technique will be tested and applied to biology investigation, including but not limited to, tissue and cell recovery in the Zebrafish (as a model organism) after laser damage. The multi-scale structural and functional image, as well as the dynamics on the protein level provided by this investigation, will potentially reveal tissue and cell recovery mechanisms, and in the long run contribute to the cure of disease along with understanding the mechanisms of tissue damage. This project will advance the state-of-the-art in optical imaging, and create new links between basic research and biological and clinical applications.

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The information about "MOIPB" are provided by the European Opendata Portal: CORDIS opendata.