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RoboCat

Molecular Robotics for Synthesis and Catalysis

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

RoboCat project word cloud

Explore the words cloud of the RoboCat project. It provides you a very rough idea of what is the project "RoboCat" about.

position machines mark sites enzymatic beginning undergoing chemical synthesis selectivity synthetic reactions usefulness structure dictating shuttled operation molecules machine catalysis demonstration biological reaction successful substrate optimize synthesize sequence fundamentally molecular construction sophisticated substrates platform model inspired successive performing transformations

Project "RoboCat" data sheet

The following table provides information about the project.

Coordinator	THE UNIVERSITY OF MANCHESTER Organization address address: OXFORD ROAD city: MANCHESTER postcode: M13 9PL website: www.manchester.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://www.catenane.net
Total cost	183˙454 €
EC max contribution	183˙454 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2016
Funding Scheme	MSCA-IF-EF-ST
Starting year	2017
Duration (year-month-day)	from 2017-07-01 to 2019-06-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE UNIVERSITY OF MANCHESTER THE UNIVERSITY OF MANCHESTER Organization address address: OXFORD ROAD city: MANCHESTER postcode: M13 9PL website: www.manchester.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (MANCHESTER)	coordinator	183˙454.00

Map

Project objective

The aim of this project is to design, synthesize and investigate the operation of synthetic molecular machines capable of performing sophisticated tasks in chemical synthesis. The molecular machines are inspired by biological systems, where substrates are shuttled between different enzymatic sites, undergoing chemical transformations at each step. Control of substrate position allows for reactions to occur in a specific sequence, with the molecular machine dictating the selectivity of each successive chemical reaction. The project both seeks to optimize the structure of the molecular machines for use as a synthetic platform and demonstrate their usefulness for synthesis and catalysis in model reactions. The successful demonstration of this concept would mark the beginning of a fundamentally new approach for the construction of molecules.

Publications

List of publications.
year	authors and title	journal	last update
2019	Chiara Biagini, Stephen D. P. Fielden, David A. Leigh, Fredrik Schaufelberger, Stefano Diâ€…Stefano, Dean Thomas Dissipative Catalysis with a Molecular Machine published pages: N/A, ISSN: 1433-7851, DOI: 10.1002/anie.201905250	Angewandte Chemie International Edition N/A	2019-10-15
2019	David A. Leigh, Lucian Pirvu, Fredrik Schaufelberger Stereoselective Synthesis of Molecular Square and Granny Knots published pages: 6054-6059, ISSN: 0002-7863, DOI: 10.1021/jacs.9b01819	Journal of the American Chemical Society 141/14	2019-10-15
2018	David A. Leigh, Lucian Pirvu, Fredrik Schaufelberger, Daniel J. Tetlow, Liang Zhang Securing a Supramolecular Architecture by Tying a Stopper Knot published pages: , ISSN: 1433-7851, DOI: 10.1002/anie.201803871	Angewandte Chemie International Edition	2019-10-15

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The information about "ROBOCAT" are provided by the European Opendata Portal: CORDIS opendata.