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DENOCS SIGNED

The Double Edged Role of Nitric Oxide and Hydrogen Peroxide in a Coral Symbiosis

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 DENOCS project word cloud

Explore the words cloud of the DENOCS project. It provides you a very rough idea of what is the project "DENOCS" about.

hydrogen    maternity    worldwide    valuable    fluorescence    environmental    innovation    climate    excellence    physiological    scenarios    lack    international    subjected    fixation    cellular    symbiont    techniques    photosymbionts    stress    prospective    dynamics    outcomes    break    combination    marine    quantitative    temporal    suitable    unclear    reefs    imaging    spatio    peroxide    sinks    hotspots    intact    oxidative    quantification    threshold    mimicking    nitrosative    2016    interdisciplinary    expert    culture    oxygen    microsensors    tools    interplay    bleaching    career    partly    mechanisms    experimental    training    species    chlorophyll    photosynthesis    biodiversity    sources    inducing    dr    nitrogen    dysfunction    underlying    coral    global    compounds    sites    experiencing    oxide    tissue    reactive    h2o2    events    assays    14c    treatments    denocs    corals    bioimaging    symbiotic    nitric    isolated    suite    date    schrameyer    restart    concentrations   

Project "DENOCS" data sheet

The following table provides information about the project.

Coordinator
KOBENHAVNS UNIVERSITET 

Organization address
address: NORREGADE 10
city: KOBENHAVN
postcode: 1165
website: www.ku.dk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Total cost 212˙194 €
 EC max contribution 212˙194 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-CAR
 Starting year 2017
 Duration (year-month-day) from 2017-06-01   to  2019-07-01

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 212˙194.00

Map

 Project objective

Global climate changes affect coral reefs worldwide and these valuable marine biodiversity hotspots are increasingly experiencing a symbiotic dysfunction known as coral bleaching, where the global bleaching events in 2016 are the most significant to date. The underlying physiological mechanisms inducing the bleaching response remain unclear. It is known that cellular oxidative stress and reactive species such as nitric oxide (NO) and hydrogen peroxide (H2O2) are involved, but the sources and sinks of these compounds, their interplay and spatio-temporal dynamics have not been investigated in corals, partly due to lack of suitable experimental tools. The DENOCS projects will apply a suite of novel quantitative assessment techniques to investigate the dynamics and impact sites of NO and H2O2 in intact corals, coral tissue culture, and isolated photosymbionts when subjected to experimental treatments mimicking global change-induced environmental stress scenarios. This will encompass expert training of Dr. Schrameyer in the use of novel microsensors for NO and H2O2 in combination with advanced bioimaging of the oxidative and nitrosative stress response in corals, variable chlorophyll fluorescence imaging and cellular 14C-fixation assays to assess symbiont photosynthesis. Prospective outcomes of DENOCS include a better understanding of oxidative and nitrosative stress responses in corals, quantification of threshold concentrations and impact sites of reactive oxygen and nitrogen species, and how these are involved in the coral bleaching response. The project DENOCS will promote EU’s research and innovation excellence through its interdisciplinary measurement approach and international collaboration, and will enable the restart of a promising career of Dr. Schrameyer after a maternity break.

 Publications

year authors and title journal last update
List of publications.
2018 Maria Moßhammer, Verena Schrameyer, Peter Ø. Jensen, Klaus Koren, Michael Kühl
Extracellular hydrogen peroxide measurements using a flow injection system in combination with microdialysis probes – Potential and challenges
published pages: 111-123, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2018.05.089
Free Radical Biology and Medicine 128 2019-08-30

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