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OLEFINE SIGNED

OLEAginous yeast platforms for FINE chemicals

Total Cost €

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EC-Contrib. €

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Partnership

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Project "OLEFINE" data sheet

The following table provides information about the project.

Coordinator
DANMARKS TEKNISKE UNIVERSITET 

Organization address
address: ANKER ENGELUNDSVEJ 1 BYGNING 101 A
city: KGS LYNGBY
postcode: 2800
website: www.dtu.dk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Project website http://www.olefine.eu
 Total cost 7˙606˙556 €
 EC max contribution 5˙442˙844 € (72%)
 Programme 1. H2020-EU.2.1.4. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology)
 Code Call H2020-NMBP-BIO-2017
 Funding Scheme IA
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    DANMARKS TEKNISKE UNIVERSITET DK (KGS LYNGBY) coordinator 432˙287.00
2    BIOPHERO APS DK (KONGENS LYNGBY) participant 2˙025˙439.00
3    LUNDS UNIVERSITET SE (LUND) participant 1˙129˙112.00
4    BIOTREND-INOVACAO E ENGENHARIA EM BIOTECNOLOGIA SA PT (CANTANHEDE) participant 485˙956.00
5    "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" EL (AGIA PARASKEVI) participant 441˙311.00
6    THE UNIVERSITY OF MANCHESTER UK (MANCHESTER) participant 250˙070.00
7    FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. DE (MUNCHEN) participant 250˙000.00
8    THE UNIVERSITY OF LIVERPOOL UK (LIVERPOOL) participant 248˙070.00
9    NOVAGRICA HELLAS ANONIMI EMPORIKI EXAGOGIKI KAI SYMVOULEFTIKI ETAIRIA BIOLOGIKON KAI CHIMIKON PROIONTON EL (ATHINA) participant 180˙596.00
10    ISCA TECHNOLOGIES, INC US (RIVERSIDE) participant 0.00

Map

 Project objective

The academic and industrial partners engaged in the OLEFINE project have the joint vision of demonstrating the techno-economic viability and sustainability of biological production of insect pheromones for use as safe and environmentally friendly insecticide substitutes. Biological production of cheaper pheromones will be a market disrupting technology that will allow rapid expansion of pheromone-based pest management products. The partners behind OLEFINE have developed a novel technology for biological production of pheromones using oleaginous yeast cell factories, however the strains, fermentation, and downstream process need to be further optimized to bring the technology to the market. OLEFINE aims to optimize, validate, and commercialize biotech process for production of high-added-value chemicals (insect pheromones) for use as non-toxic insecticide replacements. Cost-efficiency and sustainability of the current process will be lifted in this project by optimizing the yeast biocatalyst and by employing innovative fermentation and downstream processing with cascading of resources. The production cost will be reduced by at least 75% in relation to the current state-of-the-art. The process will be validated in industrial environment for two pheromones (TRL7), techno-economic viability will be estimated and business plans will be prepared. The environmental impact and sustainability will be evaluated by full Life Cycle Analysis. The technology will be brought to the market by OLEFINE industrial partners post project. In summary, OLEFINE will bring new sustainable high-value chemicals to the market and create new business opportunities and jobs in European biotech sector, which is in line with the challenge of the topic.

 Publications

year authors and title journal last update
List of publications.
2018 Carina Holkenbrink, Marie I. Dam, Kanchana R. Kildegaard, Johannes Beder, Jonathan Dahlin, David Doménech Belda, Irina Borodina
EasyCloneYALI: CRISPR/Cas9-Based Synthetic Toolbox for Engineering of the Yeast Yarrowia lipolytica
published pages: 1700543, ISSN: 1860-6768, DOI: 10.1002/biot.201700543
Biotechnology Journal 13/9 2020-01-16

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The information about "OLEFINE" are provided by the European Opendata Portal: CORDIS opendata.

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