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SENSITIVE SIGNED

Early Detection of cancer onset based on sensing field cancerization at the organ level

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

SENSITIVE project word cloud

Explore the words cloud of the SENSITIVE project. It provides you a very rough idea of what is the project "SENSITIVE" about.

purpose tumors stage cancer scattering raman microscopy platform tract worldwide ramifications lacking ones deadliest never structural gastrointestinal deal collectively death multimodal social agree health tumor visualized mechanisms symptomatic histological modality underlying alterations body detect clinical humans parties tissue organ progress fingerprints endoscope cancerization sensing gi disease measured diagnosis molecular imaging predict scans despite enormous profound biology designed treatment prevention successful sensed diseases

Project "SENSITIVE" data sheet

The following table provides information about the project.

Coordinator	IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON Organization address address: SORANOU EFESIOU 4 city: ATHINA postcode: 115 27 website: www.bioacademy.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Greece [EL]
Project website	http://www.sensitiveproject.eu
Total cost	2˙965˙326 €
EC max contribution	2˙965˙326 € (100%)
Programme	1. H2020-EU.1.2.1. (FET Open)
Code Call	H2020-FETOPEN-1-2016-2017
Funding Scheme	RIA
Starting year	2018
Duration (year-month-day)	from 2018-11-01 to 2021-10-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON Organization address address: SORANOU EFESIOU 4 city: ATHINA postcode: 115 27 website: www.bioacademy.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (ATHINA)	coordinator	541˙812.00
2	HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH Organization address address: INGOLSTADTER LANDSTRASSE 1 city: NEUHERBERG postcode: 85764 website: www.helmholtz-muenchen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (NEUHERBERG)	participant	697˙876.00
3	RIVERD INTERNATIONAL BV RIVERD INTERNATIONAL BV Organization address address: MARCONISTRAAT 16 city: ROTTERDAM postcode: 3029 AK website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ROTTERDAM)	participant	558˙125.00
4	ACADEMISCH ZIEKENHUIS GRONINGEN ACADEMISCH ZIEKENHUIS GRONINGEN Organization address address: HANZEPLEIN 1 city: GRONINGEN postcode: 9713 GZ website: www.umcg.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (GRONINGEN)	participant	438˙781.00
5	UNIVERSIDAD CARLOS III DE MADRID UNIVERSIDAD CARLOS III DE MADRID Organization address address: CALLE MADRID 126 city: GETAFE (MADRID) postcode: 28903 website: http://www.uc3m.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (GETAFE (MADRID))	participant	362˙187.00
6	RAYFOS LTD RAYFOS LTD Organization address address: WINTON HOUSE WINTON SQUARE city: BASINGSTOKE postcode: RG21 8EN website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (BASINGSTOKE)	participant	231˙918.00
7	MARIOS LYMARAKIS KAI SIA EE MARIOS LYMARAKIS KAI SIA EE Organization address address: ETHNIKIS ANTISTASEOS 132 city: GERAKAS ATTIKI postcode: 15344 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (GERAKAS ATTIKI)	participant	134˙625.00

Map

Project objective

Cancer is a major cause of death worldwide. Gastrointestinal (GI) tract tumors are among the most common and deadliest ones. Despite progress in imaging and treatment, the social impact of these diseases is enormous. All parties in the health sector agree that prevention and/or early diagnosis is the most effective means to deal with cancer. Currently, cancer is identified most often when symptomatic or large enough to be visualized in body scans or when histological alterations are already present. What is lacking is an imaging method that could detect tissue changes that facilitate or predict tumor development at an early stage. These alterations, collectively referred to as “field cancerization” is an exciting field of study in cancer biology with profound ramifications in clinical practice. Molecular mechanisms underlying field cancerization are being studied and the advances in molecular biology facilitate these studies. Never in the past however, have these changes been sensed/measured by an imaging modality at the organ level. We thus propose the development of a multimodal microscopy platform that will allow sensing of Raman and scattering properties at the organ level, in order to identify molecular and structural fingerprints of early stage disease in the GI tract. Successful implementation will allow the development of an endoscope especially designed for this purpose that will be used to detect early stage cancer in humans.

Deliverables

List of deliverables.
Data Management Plan	Open Research Data Pilot	2020-02-07 15:50:22

Take a look to the deliverables list in detail: detailed list of SENSITIVE deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Albert-Smet, Ignacio; Marcos-Vidal, Asier; Vaquero, Juan JosÃ©; Desco, Manuel; MuÃ±oz-Barrutia, Arrate; Ripoll, Jorge Applications of Light-Sheet Microscopy in Microdevices published pages: , ISSN: 1662-5129, DOI: 10.3389/fnana.2019.00001	Frontiers in Neuroanatomy 1	2020-02-05

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The information about "SENSITIVE" are provided by the European Opendata Portal: CORDIS opendata.