Opendata, web and dolomites

PROFID SIGNED

Implementation of personalised risk prediction and prevention of sudden cardiac death after myocardial infarction

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 PROFID project word cloud

Explore the words cloud of the PROFID project. It provides you a very rough idea of what is the project "PROFID" about.

death    tool    health    le    post    device    decision    majority    datasets    care    complications    infarction    companies    patient    composition    heart    icd    yearly    stops    accounting    350    healthcare    chains    predict    is    expenditures    benefit    pilot    potentially    regions    clinical    prevent    registries    guidelines    score    lvef    severe    implantable    left    routine    individual    software    beating    minutes    opinion    trials    gt    dies    20    makers    incidence    defibrillator    cardioverter    implantation    prevented    considerable    hospital    minority    optimally    deaths    geographies    scd    public    personalised    policy    recommend    run    international    successfully    urgently    fraction    parallel    patients    cohorts    suddenly    insurance    700    inherent    myocardial    cardiac    treatment    historical    profid    prophylactic    ejection    untreated    validate    leaders    randomised    sudden    35    risks    economic    risk    absolute    unexpectedly    ventricular    participation    mi    occurs    payers   

Project "PROFID" data sheet

The following table provides information about the project.

Coordinator
LEIPZIG HEART INSTITUTE GMBH 

Organization address
address: RUSSENSTRASSE 69A
city: LEIPZIG
postcode: 4289
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 23˙381˙704 €
 EC max contribution 19˙884˙569 € (85%)
 Programme 1. H2020-EU.3.1.6. (Health care provision and integrated care)
 Code Call H2020-SC1-2019-Two-Stage-RTD
 Funding Scheme IA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2024-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    LEIPZIG HEART INSTITUTE GMBH DE (LEIPZIG) coordinator 7˙076˙062.00
2    CRI - THE CLINICAL RESEARCH INSTITUTE GMBH DE (MUNCHEN) participant 6˙767˙383.00
3    ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) participant 931˙250.00
4    THE UNIVERSITY OF MANCHESTER UK (MANCHESTER) participant 899˙168.00
5    UNIVERSITY OF YORK UK (YORK NORTH YORKSHIRE) participant 767˙806.00
6    UNIVERSITAT BAYREUTH DE (BAYREUTH) participant 399˙625.00
7    UNIVERSITY OF LEEDS UK (LEEDS) participant 295˙000.00
8    SOCIETE EUROPEENNE DE CARDIOLOGIE FR (BIOT SOPHIA ANTIPOLIS) participant 248˙125.00
9    Catalyze B.V. NL (AMSTERDAM-DUIVENDRECHT) participant 243˙687.00
10    QS INSTITUTO DE INVESTIGACION E INNOVACION SL ES (MADRID) participant 221˙628.00
11    DEUTSCHE HERZSTIFTUNG EV DE (FRANKFURT AM MAIN) participant 198˙750.00
12    SLASKI UNIWERSYTET MEDYCZNY W KATOWICACH PL (KATOWICE) participant 185˙437.00
13    FAKULTNI NEMOCNICE OLOMOUC CZ (OLOMOUC) participant 185˙000.00
14    REGION STOCKHOLM SE (STOCKHOLM) participant 185˙000.00
15    SEMMELWEIS EGYETEM HU (BUDAPEST) participant 185˙000.00
16    THE HEALTH CORPORATION - RAMBAM IL (HAIFA) participant 185˙000.00
17    BARMER ERSATZKASSE DE (WUPPERTAL) participant 172˙708.00
18    CLINIQUE PASTEUR SA FR (TOULOUSE CEDEX 3) participant 167˙562.00
19    ISTITUTO AUXOLOGICO ITALIANO IT (MILANO) participant 151˙875.00
20    ASTON UNIVERSITY UK (BIRMINGHAM) participant 150˙000.00
21    AARHUS UNIVERSITETSHOSPITAL DK (AARHUS) participant 135˙000.00
22    INSTITUTO INVESTIGACION SANITARIA FUNDACION JIMENEZ DIAZ ES (MADRID) participant 83˙500.00
23    AARHUS UNIVERSITET DK (AARHUS C) participant 50˙000.00

Map

 Project objective

Sudden cardiac death (SCD) is a major public health problem accounting for ~20% of all deaths in Europe with an estimated yearly incidence of ~350-700,000, often in patients with previous myocardial infarction (MI). In SCD, the heart suddenly and unexpectedly stops beating. If untreated, the patient dies within minutes, but SCD can be successfully prevented by an implantable cardioverter-defibrillator (ICD). The ICD is highly effective, but is associated with potentially severe complications and high healthcare costs. Based on historical evidence, guidelines recommend prophylactic ICD implantation in post-MI patients with left ventricular ejection fraction (LVEF)≤35% to prevent SCD. However, only a minority of these patients will ever need the device. In addition, in absolute numbers the majority of SCD cases occurs in patients with LVEF>35% who are currently not considered for prophylactic ICD. Due to the inherent risks and considerable health care expenditures, a personalised treatment approach for ICD implantation is urgently required. Using state-of-the-art methods and large clinical datasets from established international cohorts and registries across different European geographies, PROFID will develop a clinical decision support tool (risk score) to predict the individual SCD risk and identify those post-MI patients that will optimally benefit from an ICD. Two parallel randomised clinical trials will validate implementation of the risk score to determine ICD implantation, while health economic analyses will assess its economic impact on health care systems. A software tool for clinical use of the risk score will be implemented, and a pilot run in 3 European regions with participation of insurance companies and authorities. The unique composition of the consortium with key opinion leaders, patient organisations, large hospital chains, payers, policy makers and state authorities across Europe, will ensure implementation into routine clinical practice.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PROFID" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "PROFID" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.3.1.6.)

EBRA (2018)

European Brain Research Area

Read More  

SAPHIRE (2018)

Securing Adoption of Personalised Health in REgions

Read More  

HTx (2019)

Next Generation Health Technology Assessment to support patient-centred, societally oriented, real-time decision-making on access and reimbursement for health technologies throughout Europe

Read More