IACOBUS
"Diagnosis and Monitoring of Inflammatory and Arthritic diseases using a COmbined approach Based on Ultrasound, optoacoustic and hyperSpectral imaging"
| Coordinatore | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V
Organization address
address: Hansastrasse 27C contact info |
| Nazionalità Coordinatore | Germany [DE] |
| Totale costo | 3˙837˙268 € |
| EC contributo | 3˙046˙476 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2012-INNOVATION-1 |
| Funding Scheme | CP-FP |
| Anno di inizio | 2013 |
| Periodo (anno-mese-giorno) | 2013-01-01 - 2015-12-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V
Organization address
address: Hansastrasse 27C contact info |
DE (MUENCHEN) | coordinator | 697˙888.00 |
| 2 |
NORSK ELEKTRO OPTIKK AS
Organization address
address: SOLHEIMVEIEN 62 A contact info |
NO (LORENSKOG) | participant | 765˙042.00 |
| 3 |
NORGES TEKNISK-NATURVITENSKAPELIGEUNIVERSITET NTNU
Organization address
address: HOGSKOLERINGEN 1 contact info |
NO (TRONDHEIM) | participant | 564˙648.00 |
| 4 |
VERMON SA
Organization address
address: RUE DU GENERAL RENAULT 180 contact info |
FR (TOURS CEDEX 1) | participant | 384˙518.00 |
| 5 |
TP21 GMBH
Organization address
address: LUISENSTRASSE 14 contact info |
DE (BERLIN) | participant | 235˙680.00 |
| 6 |
JUSTUS-LIEBIG-UNIVERSITAET GIESSEN
Organization address
address: Ludwigstrasse 23 contact info |
DE (GIESSEN) | participant | 230˙400.00 |
| 7 |
EKSPLA UAB
Organization address
address: SAVANORIU PR 231 contact info |
LT (VILNIUS) | participant | 168˙300.00 |
Mappa
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Obiettivo del progetto (Objective)
'Rheumatoid arthritis (RA) and psoriasis arthritis (PSA) are destructive polyarthritic diseases having high incidence rates worldwide of about 1,5% and 0,5% respectively. Arthritis-related joint destruction leads to disabilities which result in a loss of patient’s quality of life, often include an inability to work and significant costs for healthcare systems. The functional outcome is strongly dependent on the time lag between the onset of the disease and the treatment beginning (ideally < 3-6 months). For early diagnosis allowing to improve the course of this devastating disease, sensitive and accurate diagnostic tools are required. Further, excellent image quality is needed for differentiated diagnosis (osteoarthritis vs RA or PSA) permitting the stratification of patient groups required for enabling a personalized therapeutical approach. Therefore, tools for early, precise and reliable diagnosis being affordable for screenings are of highest importance. Within IACOBUS, we suggest a new multimodal approach combining hyperspectral imaging with ultrasound (US) and optoacoustic (OA) techniques for diagnosis of arthritic diseases in finger joints. The proposed concept will allow the diagnosis and monitoring of arthritis based on imaging of early inflammation-induced hyperperfusion. Hyperspectral overview imaging for identification of suspicious joints will be combined with detailed high-resolution 3D imaging of affected joints (OA/US). Osteochondral information will be provided by high-frequency US while OA imaging will allow the high-sensitivity imaging of microvasculature in inflamed tissue. The consortium consisting of 4 SMEs and 3 academic partners will develop a novel non-invasive image-based diagnostic tool with significantly enhanced sensitivity for early arthritis symptoms and thereby allow to make use of the therapeutical window of opportunities. 50% of the overall project budget will go to SMEs which will ensure the exploitation of the developed platform.'