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DURETO

Rearm cultivated tomato with natural and durable resistance mechanisms from wild tomato species

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 DURETO project word cloud

Explore the words cloud of the DURETO project. It provides you a very rough idea of what is the project "DURETO" about.

leaf    pesticides    insecticides    post    natural    protected    trichomes    stem    combining    seem    collection    markers    led    defend    molecular    terpene    biology    species    cultivated    re    neonicotinoids    epizingiberene    industry    banned    transcripts    researcher    genomic    small    shown    themselves    corresponding    data    independent    messenger    vegetable    defence    genomes    enhanced    accessions    biostatistics    mechanisms    associate    regulatory    commercially    biosynthetic    glandular    discover    toxic    previously    hairs    breeding    govern    me    metabolic    bioinformatics    plant    regulation    incorporation    tomatoes    compounds    surface    rnas    polymorphisms    sequence    material    successful    producing    environments    consequently    translated    regulations    background    effect    extensive    quantitatively    threat    resistance    tomato    transcriptional    introduction    phenotypic    follow    phenotypes    mapping    wild    insect    insects    gaining    repellent    compare    stored   

Project "DURETO" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITEIT VAN AMSTERDAM 

Organization address
address: SPUI 21
city: AMSTERDAM
postcode: 1012WX
website: www.uva.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Project website http://gls.uva.nl/profile/b/l/p.m.bleeker/p.m.bleeker.html
 Total cost 165˙598 €
 EC max contribution 165˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-05-01   to  2017-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) coordinator 165˙598.00

Map

 Project objective

Insects are gaining resistance to commercially available pesticides and effective insecticides (e.g. neonicotinoids) are currently being banned. Consequently, there is a real threat that the EU vegetable production will be affected. Wild tomato species have the ability to defend themselves by producing natural defence compounds that have a toxic or repellent effect on insects. These compounds are produced and stored in glandular hairs (trichomes) on the plant stem and leaf surface. Extensive breeding in protected environments led to the loss of these defence compounds in cultivated tomatoes. It was previously shown that the introduction of the terpene 7-epizingiberene biosynthetic pathway from a wild tomato in trichomes of cultivated tomato results in an enhanced resistance to insects. However, the regulatory factors that govern the production of these defence compounds seem also essential for successful incorporation of ‘wild resistance’ into breeding material. Here, I aim to discover metabolic defence mechanisms present in the trichomes of wild tomato species that can be re-introduced into cultivated tomato with a focus on post-transcriptional regulation of biosynthetic pathways. I will evaluate insect resistance in a collection of wild and cultivated tomato accessions and associate phenotypic and transcriptional data via a Systems Biology approach. I will also sequence small RNAs and compare them quantitatively with messenger RNAs to identify post-transcriptional regulations. Next, I will follow a comparative genomic approach by mapping the selected transcripts to their corresponding tomato genomes to associate polymorphisms and resistance phenotypes. These results will be directly translated into molecular markers that the industry can implement in breeding programmes. This proposal will help me become an independent researcher, combining my background in plant biology with knowledge on bioinformatics, biostatistics and state-of-the-art technology.

 Publications

year authors and title journal last update
List of publications.
2016 Paula J. M. van Kleeff, Marc Galland, Robert C. Schuurink, Petra M. Bleeker
Small RNAs from Bemisia tabaci Are Transferred to Solanum lycopersicum Phloem during Feeding
published pages: , ISSN: 1664-462X, DOI: 10.3389/fpls.2016.01759
Frontiers in Plant Science 7 2019-07-23

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The information about "DURETO" are provided by the European Opendata Portal: CORDIS opendata.

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