#	Pagina
attuale pagina	/open-h2020/projects/196344/index.html

Opendata, web and dolomites

uDAS

An Automatic Microfluidic Device Assembly System

Total Cost €

EC-Contrib. €

Partnership

Views

uDAS project word cloud

Explore the words cloud of the uDAS project. It provides you a very rough idea of what is the project "uDAS" about.

expensive standard academia assays limited first tool generation 85 semi full uncontrolled suffered reactions thousands protein microarray multilayer sophisticated yield fabrication proven prototype layers multidimensional microfluidic sciences 2012 glass lithography benefit uses contains road pdms mudloc fabricate designed expertise consist multiple mainly das platform portability layer dimensional dimensions automated times serial array last ed pave reagents soft micromechanical microfluidics assembly solution platforms construction device almost automatic biomedical sequence chips 15 critical hundreds demands frustrating manufactured half existent micrometer convenient valves erc complexity micro 2nd direct parallel penetration industry life density

Project "uDAS" data sheet

The following table provides information about the project.

Coordinator	BAR ILAN UNIVERSITY Organization address address: BAR ILAN UNIVERSITY CAMPUS city: RAMAT GAN postcode: 52900 website: www.biu.ac.il contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Israel [IL]
Total cost	150˙000 €
EC max contribution	150˙000 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2014-PoC
Funding Scheme	ERC-POC
Starting year	2015
Duration (year-month-day)	from 2015-04-01 to 2016-09-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	BAR ILAN UNIVERSITY BAR ILAN UNIVERSITY Organization address address: BAR ILAN UNIVERSITY CAMPUS city: RAMAT GAN postcode: 52900 website: www.biu.ac.il contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (RAMAT GAN)	coordinator	150˙000.00

Map

Project objective

Microfluidic systems, in general, have proven important platforms for biomedical assays. These systems benefit from reduced requirements for expensive reagents, short analysis times, and portability. Although microfluidic systems are convenient platforms, their use in the life sciences is still limited mainly due to the high-level fabrication expertise required for construction.

Integrated microfluidics is one of the most sophisticated three-dimensional (multi layer) solution. It requires soft lithography (PDMS based chips), for production of high complexity microfluidic systems (multiple serial or parallel processes). Integrated microfluidics in particular is almost non-existent in the industry due to the low yield and uncontrolled production process.

My ERC project (MUDLOC-2012) is to develop a microfluidic platform for multidimensional protein array analysis. It uses complex multilayer microfluidic devices that consist of 2 PDMS layers and a glass microarray. The integrated microfluidics system contains thousands of micromechanical valves in micrometer dimensions, controlling thousands of parallel reactions. Our research demands production of hundreds of such devices.

We, as all others who produce integrated microfluidics, suffered from frustrating low yield (15%). In order to improve fabrication yield and to fabricate devices with increased density, we designed and manufactured, a first of its kind, full production process sequence, semi automatic Microfluidic Device Assembly System (µDAS). This resulted in a direct increase of device complexity and yield (85%) over the last half year.

The 2nd generation automated µDAS prototype will become a generic assembly tool for soft lithography. µDAS will enable a critical production standard and process control, which will pave the road for significant penetration of complex integrated microfluidics technology into both academia and industry.

Publications

List of publications.
year	authors and title	journal	last update
2016	Dorit Avirahami, Sarit Kipper, Yair Glick, Ludmila Frolov, Ortal Guy, Efrat Michaely ON-The-Fly Microfluidic Device Assembly published pages: , ISSN: , DOI:	EMBL Conference Microfluidics 2016 1 every two years	2019-07-24
2017	Sarit Kipper, Ludmila Frolov, Ortal Guy, Michal Pellach, Yair Glick, Asaf Malichi, Binyamin A. Knisbacher, Efrat Barbiro-Michaely, Dorit Avrahami, Yehuda Yavets-Chen, Erez Y. Levanon, Doron Gerber Control and automation of multilayered integrated microfluidic device fabrication published pages: 557-566, ISSN: 1473-0197, DOI: 10.1039/C6LC01534D	Lab Chip 17/3	2019-07-24
2016	Glick Y., Ben-ari Y., Schwartz N., Nevenzal H., Ronen M., Kipper S., Golodnitsky R., Chen D., Avrahami D., Barbiro-michaely E., Gerber D. Alignment in multilayer microfluidics device A stumbling block published pages: , ISSN: , DOI:		2019-07-24

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "UDAS" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "UDAS" are provided by the European Opendata Portal: CORDIS opendata.