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CHIRALSENSE

CHIRALSENSE : Sensing Chirality using cavity-enhanced polarimetry: advances in sensitivity and time-resolution

Total Cost €

0

EC-Contrib. €

0

Partnership

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 CHIRALSENSE project word cloud

Explore the words cloud of the CHIRALSENSE project. It provides you a very rough idea of what is the project "CHIRALSENSE" about.

filing    et    chemical    improvements    requiring    reduce    performance    absolute    magnitude    standard    cd    sofikitis    time    removed    dichroism    adapt    sensing    polarimetric    multibillion    enhanced    triceps    sizes    size    follow    signal    signals    nature    techniques    protection    optical    chromatography    backgrounds    2014    stages    give    514    al    cosmetic    demonstrated    resolution    structure    industry    separated    small    pharmaceutical    commercially    industries    circular    respect    76    polarimeter    orders    constituting    performing    companies    protein    grant    passes    chiralsense    constraints    place    cavity    samples    rotation    quality    provisional    file    analytical    hplc    liquid    1000    reversals    food    advantages    suppressed    groundbreaking    detection    severe    sensitivity    null    chiral    chemistry    polarimetry    ipr    acquisition    patent    first    birefringent    commercial    ranging    polarimeters    erc   

Project "CHIRALSENSE" data sheet

The following table provides information about the project.

Coordinator
IDRYMA TECHNOLOGIAS KAI EREVNAS 

Organization address
address: N PLASTIRA STR 100
city: IRAKLEIO
postcode: 70013
website: www.forth.gr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Greece [EL]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-PoC
 Funding Scheme ERC-POC
 Starting year 2015
 Duration (year-month-day) from 2015-04-01   to  2016-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IDRYMA TECHNOLOGIAS KAI EREVNAS EL (IRAKLEIO) coordinator 150˙000.00

Map

 Project objective

Chiral sensing is crucial to many fields, constituting a multibillion Euro industry. The polarimetric techniques of optical rotation (OR) and circular dichroism (CD) are the most widely-used techniques for the analysis of chiral samples, ranging from the measurement of protein structure, to quality control in the pharmaceutical, chemical, cosmetic, and food industries. In general, the OR and CD signals are very small, which place severe constraints on detection sensitivity and time-resolution. Through the ERC grant TRICEPS, we have developed a groundbreaking cavity-based polarimeter [Sofikitis et al. Nature 514, 76 (2014)] with 3 main advantages: (a) The OR and CD signals are enhanced by the number of cavity passes (typically 1000); (b) birefringent backgrounds are suppressed; (c) signal reversals give absolute polarimetry measurements, not requiring the sample to be removed to measure a null sample. These advantages represent orders-of-magnitude improvements in sensitivity, acquisition time, and sample size, with respect to commercially available polarimeters, and will reduce measurement time, sample sizes, and costs in the chiral sensing industry. We propose, through CHIRALSENSE, to: (1) file a non-provisional US patent application, to follow our filing of a US provisional patent application for our polarimeter, which will provide IPR protection for the first stages of the product development; (2) demonstrate our existing CHIRALSENSE polarimeter to leading polarimetry companies, by performing measurements on commercial-standard samples; and (3) adapt our polarimeter to measure complex samples separated using HPLC (high-performance liquid chromatography) for analytical chemistry applications, to be demonstrated to leading HPLC companies.

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The information about "CHIRALSENSE" are provided by the European Opendata Portal: CORDIS opendata.

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