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ARRAY SEQ
Array-tagged single cell gene expression by parallel linear RNA amplification and sequencing
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0ARRAY SEQ project word cloud
Explore the words cloud of the ARRAY SEQ project. It provides you a very rough idea of what is the project "ARRAY SEQ" about.
combines
game
coming
expression
profile
few
commercially
magnitude
protocol
unimaginable
membrane
limited
tumor
millions
affordably
personal
differentially
medicine
capturing
reinvents
hands
instruments
little
unlike
analyzing
breadth
tremendously
microarray
amounts
easily
parallel
previously
cell
scaled
million
reagents
technique
cel
dna
tagging
gene
tremendous
blood
transcriptomes
expensive
examined
laborious
platform
transcriptomics
versatility
lab
orders
array
technologies
single
biology
hundreds
commercial
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invented
cells
query
changer
seq
biomedical
clinical
published
completely
least
Project "ARRAY SEQ" data sheet
The following table provides information about the project.
| Coordinator |
TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Organization address contact info |
| Coordinator Country | Israel [IL] |
| Total cost | 150˙000 € |
| EC max contribution | 150˙000 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2015-PoC |
| Funding Scheme | ERC-POC |
| Starting year | 2015 |
| Duration (year-month-day) | from 2015-09-01 to 2017-02-28 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY | IL (HAIFA) | coordinator | 150˙000.00 |
Map
Project objective
In many biomedical research and clinical applications it would be tremendously useful to know the gene expression profile of each and every cell in a sample, be it a blood sample or tumor. At present, the most advanced single-cell technologies are limited to a few thousand cells by a laborious and expensive approach. We have invented a method allowing the determination of the transcriptomes of millions of cells in parallel, using array-based technique for tagging single cells. The protocol combines our previously published protocol for single cell transcriptomics – CEL-Seq – with a new membrane based system for capturing single cells and a DNA microarray for differentially tagging each cell in the membrane. If further developed into a commercial platform, our method could have tremendous impact on clinical and research transcriptomics. Our method requires no expensive equipment, low amounts of reagents and little hands-on, making it unlike any available protocol for single cell analysis. Our method also has great versatility as it can be used for analyzing up to a million cells, but can also be easily scaled down to several hundreds, promising to make it the state of the art protocol for any lab interested in single cell biology. Our method thus represents a game-changer because it completely reinvents the scale under which cells can be examined – affordably and without a need for expensive instruments – by at least three orders of magnitude. The aim of this project is to establish a user-friendly platform for our method that could be commercially available in the coming years. The developed platform will facilitate a large-scale ability to query cells; the breadth of possible research and personal medicine applications is unimaginable at present.
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The information about "ARRAY SEQ" are provided by the European Opendata Portal: CORDIS opendata.
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