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FORMILK SIGNED

Innovative technology for the detection of enzyme activity in milk

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

FORMILK project word cloud

Explore the words cloud of the FORMILK project. It provides you a very rough idea of what is the project "FORMILK" about.

technologies ultrasonic levels sme company lactose manufacturing efficient validation dairy canada six diet assays staff priorities electrochemical enzymes academic free lactase governmental applicable laboratories detection surfaces slovakia smes sensor acoustic workshops exchange ireland of spectroscopy plasmin enzyme commercialised organisation transfer surface hungary nanofabricated volume milk usa farms business training industry schools output industrial students resolution analytical world drinks

Project "FORMILK" data sheet

The following table provides information about the project.

Coordinator	UNIVERZITA KOMENSKEHO V BRATISLAVE Organization address address: SAFARIKOVO NAM 6 city: BRATISLAVA postcode: 814 99 website: http://www.uniba.sk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Slovakia [SK]
Project website	http://www.formilk.fmph.uniba.sk
Total cost	1˙323˙000 €
EC max contribution	1˙228˙500 € (93%)
Programme	1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
Code Call	H2020-MSCA-RISE-2015
Funding Scheme	MSCA-RISE
Starting year	2016
Duration (year-month-day)	from 2016-01-01 to 2019-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERZITA KOMENSKEHO V BRATISLAVE UNIVERZITA KOMENSKEHO V BRATISLAVE Organization address address: SAFARIKOVO NAM 6 city: BRATISLAVA postcode: 814 99 website: http://www.uniba.sk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SK (BRATISLAVA)	coordinator	409˙500.00
2	TERMESZETTUDOMANYI KUTATOKOZPONT TERMESZETTUDOMANYI KUTATOKOZPONT Organization address address: MAGYAR TUDOSOK KORUTJA 2 city: BUDAPEST postcode: 1117 website: www.ttk.mta.hu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	HU (BUDAPEST)	participant	301˙500.00
3	UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN Organization address address: BELFIELD city: DUBLIN postcode: 4 website: www.ucd.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	participant	193˙500.00
4	POWERTEC SRO POWERTEC SRO Organization address address: DROTARSKA 6385/19a city: BRATISLAVA postcode: 811 04 website: www.powertec.sk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SK (BRATISLAVA)	participant	180˙000.00
5	MAGYAR TEJGAZDASAGI KISERLETI INTEZET KORLATOLT FELELOSSEGU TARSASAG MAGYAR TEJGAZDASAGI KISERLETI INTEZET KORLATOLT FELELOSSEGU TARSASAG Organization address address: LUCSONY UTCA 24 city: MOSONMAGYAROVAR postcode: 9200 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	HU (MOSONMAGYAROVAR)	participant	121˙500.00
6	SONAS TECHNOLOGIES LIMITED SONAS TECHNOLOGIES LIMITED Organization address address: 42 AILESBURY GROVE DUNDRUM city: DUBLIN postcode: 16 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	participant	13˙500.00
7	CROSSCARE LIMITED CROSSCARE LIMITED Organization address address: FIRST FLOOR THE HERBERT BUILDING THE PARK CARRICKMINES city: DUBLIN postcode: 18 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	participant	9˙000.00
8	THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO Organization address address: KINGS COLLEGE CIRCLE 27 city: TORONTO postcode: M5S 1A1 website: http://www.utoronto.ca/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CA (TORONTO)	partner	0.00
9	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA Organization address address: FRANKLIN STREET 1111, 12 FLOOR city: OAKLAND CA postcode: 94607 website: http://www.universityofcalifornia.edu/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (OAKLAND CA)	partner	0.00
10	UT BATTELLE LLC UT BATTELLE LLC Organization address address: BETHEL VALLEY ROAD city: OAK RIDGE TENNESSEE postcode: 37831 6265 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (OAK RIDGE TENNESSEE)	partner	0.00

Map

Project objective

The proposal is focused on the development of novel methods of detection of activity of enzymes, such as plasmin and lactase, important for milk industry and for lactose-free diet. Six experienced academic/research institutions, two SMEs, one governmental business company and one manufacturing company from 3 EU member states (Slovakia, Hungary, Ireland), USA and Canada will be involved in the research, development and validation. The main focus will be on application of high-resolution ultrasonic spectroscopy, surface acoustic and electrochemical methods involving nanofabricated surfaces for detection of enzyme activity in volume and at the surfaces. The output of the project will be the novel analytical assays and electrochemical sensor applicable in dairy farms and analytical laboratories, staff exchange between academic institutions and SME, training of the students in novel analytical methods and sensor developments in a world leading laboratories. The optimised enzyme based technologies for efficient control of levels of lactose in milk and milk based drinks will be one of important results of project, which could be commercialised by the project industrial participants. The organisation of training schools, workshops and transfer of novel technology will be among priorities of this proposal.

Deliverables

List of deliverables.
Miniature potentiostat, software and sensor	Demonstrators, pilots, prototypes	2020-04-14 21:34:09
Protocol of enzyme assay in a volume	Documents, reports	2020-04-14 21:34:10
Report on secondments	Documents, reports	2020-04-14 21:34:10
Open Research Data Pilot	Open Research Data Pilot	2020-04-14 21:34:10
Peer reviewed articles	Documents, reports	2020-04-14 21:34:10
Protocol of enzyme assay at surfaces	Documents, reports	2020-04-14 21:34:09
Second progress report	Documents, reports	2020-04-14 21:34:09
Data Management Plan	Documents, reports	2020-04-14 21:34:07
First progress report	Documents, reports	2020-04-14 21:34:09
Website	Websites, patent fillings, videos etc.	2020-04-14 21:34:09
Workshops and summer schools	Demonstrators, pilots, prototypes	2020-04-14 21:34:09
Mid-term meeting	Other	2020-04-14 21:34:07

Take a look to the deliverables list in detail: detailed list of FORMILK deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	T. Szabo, B. Csupor, P. Pekker, Z. Keresztes Tunable size gold nanoparticle-enzyme substrate conjugates: posible sensor applications published pages: 176, ISSN: , DOI:	Book of Abstracts, Matrafured 2019, International Conference on Chemical Sensors, Visegrad, Hungary, 2019 June 16-21, 2019	2020-04-14
2019	Zuzana GaraiovÃ¡, Gulcin Bolat, Berta Esteban-FernÃ¡ndez de Ãvila, Hua Gong, Natalia Sanz del Olmo, Paula Ortega, Francisco Javier de la Mata, Sylwia Michlewska, Joseph Wang, Tibor Hianik Combination of Ruthenium Dendrimers and Acoustically Propelled Gold Nanowires as a Platform for Active Intracellular Drug Delivery Towards Breast Cancer Therapy published pages: 1-5, ISSN: 2613-4942, DOI: 10.31487/j.cor.2019.04.08	Clinical Oncology and Research	2020-04-14
2019	Veronika Stepanova, Vladimir Smolko, Vladimir Gorbatchuk, Ivan Stoikov, Gennady Evtugyn, Tibor Hianik DNA-Polylactide Modified Biosensor for Electrochemical Determination of the DNA-Drugs and Aptamer-Aflatoxin M1 Interactions published pages: 4962, ISSN: 1424-8220, DOI: 10.3390/s19224962	Sensors 19/22	2020-04-14
2019	Gennady Evtugyn, Tibor Hianik Electrochemical Immuno- and Aptasensors for Mycotoxin Determination published pages: 10, ISSN: 2227-9040, DOI: 10.3390/chemosensors7010010	Chemosensors 7/1	2020-04-14
2018	Stefanos Karapetis, Dimitrios Nikolelis, Tibor Hianik Label-Free and Redox Markers-Based Electrochemical Aptasensors for Aflatoxin M1 Detection published pages: 4218, ISSN: 1424-8220, DOI: 10.3390/s18124218	Sensors 18/12	2020-04-14
2018	LorÃ¡nd RomÃ¡nszki, Marek Tatarko, Mengchi Jiao, ZsÃ³fia Keresztes, Tibor Hianik, Michael Thompson Casein probeâ€“based fast plasmin determination in the picomolar range by an ultra-high frequency acoustic wave biosensor published pages: 206-214, ISSN: 0925-4005, DOI: 10.1016/j.snb.2018.08.025	Sensors and Actuators B: Chemical 275	2020-04-14
2018	Marek Tatarko, Eric S. Muckley, Veronika Subjakova, Monojoy Goswami, Bobby G. Sumpter, Tibor Hianik, Ilia N. Ivanov Machine learning enabled acoustic detection of sub-nanomolar concentration of trypsin and plasmin in solution published pages: 282-288, ISSN: 0925-4005, DOI: 10.1016/j.snb.2018.05.100	Sensors and Actuators B: Chemical 272	2020-04-14
2017	J. Byrne ColiefÂ® lactase enzyme infant drops product origin and application development published pages: 9, ISSN: , DOI:	\"International workshop \"\"Recent applications of high-resolution ultrasonic spectroscopy for monitoring of hydrolytic activities in milks\"\"\" November 2017	2020-04-14
2018	Vitaly Buckin High-resolution ultrasonic spectroscopy published pages: 207-217, ISSN: 2194-878X, DOI: 10.5194/jsss-7-207-2018	Journal of Sensors and Sensor Systems 7/1	2020-04-14
2017	J. Nagy, Z. S. SteinernÃ©, A. Poturnayova, A. Hucker, K. Szabo, T. Hianik Detection of microorganisms in food products by atomic force microscopy published pages: 12, ISSN: , DOI:	\"International workshop \"\"Recent applications of high-resolution ultrasonic spectroscopy for monitoring of hydrolytic activities in milks\"\"\" November 2017	2020-04-14
2018	M. Dizon, M. Caras-Altas, V. Buckin Application of high resolution ultrasonic spectroscopy (HRâ€“US) on realtime monitoring of whey protein hydrolysis published pages: , ISSN: , DOI:	Book of Abstracts, Third Year PhD Talks 2018, Dublin Chemistry Graduate Seminars 2017-18 29th May, 2018	2020-04-14
2017	V. Buckin , M. Altas Ultrasonic Monitoring of Biocatalysis in Solutions and Complex Dispersions published pages: 336, ISSN: 2073-4344, DOI: 10.3390/catal7110336	Catalysts 7/11	2020-04-14
2017	I. Piovarci, A. Poturnayova, J. Nagy, R. Sarok, T. Hianik Development of acoustic sensor for detection chymotrypsin activity at surfaces published pages: 218, ISSN: , DOI:	BioSensor 2017,1st European and 10th German BioSensor Symposium 2017	2020-04-14
2017	Marek Tatarko, Ilia N. Ivanov, Tibor Hianik Stability monitoring of casein layer on hydrophilic SO2 surface using quartz crystal microbalance with dissipation published pages: 178, ISSN: , DOI:	BioSensors 2017, 1st European and 10th German BioSensor Symposium, Potsdam, Germany 2017	2020-04-14
2018	Vladimir Smolko, Dmitry Shurpik, Anna Porfireva, Gennady Evtugyn, Ivan Stoikov, Tibor Hianik Electrochemical Aptasensor Based on Poly(Neutral Red) and Carboxylated Pillar[5]arene for Sensitive Determination of Aflatoxin M1 published pages: 486-496, ISSN: 1040-0397, DOI: 10.1002/elan.201700735	Electroanalysis 30/3	2020-04-14
2016	Eric S. Muckley, Cristain Anazagasty, Christopher B. Jacobs, Tibor Hianik, Ilia N. Ivanov Low-cost scalable quartz crystal microbalance array for environmental sensing published pages: 99440Y, ISSN: , DOI: 10.1117/12.2237942	Organic Sensors and Bioelectronics IX	2020-04-14
2017	Tibor Hianik, Christer L. Ã˜pstad, Jana Å andorovÃ¡, Zuzana GaraiovÃ¡, Vassilia Partali, Hans-Richard Sliwka Surface properties of polyene glycol phospholipid monolayers published pages: 13-20, ISSN: 0009-3084, DOI: 10.1016/j.chemphyslip.2016.11.007	Chemistry and Physics of Lipids 202	2020-04-14
2016	A. Poturnayova, M. Tatarko, I. Karpisova, G. Castillo, Z. Keresztes, T. Hianik Detection of plasmin based on specific peptide substrate and casein using acousttic transducer published pages: P3.161, ISSN: , DOI:	26 Aniversary World Congress on Biosensors, Gothenburg, Sweden 25-27 May 2016	2020-04-14
2017	M. Tatarko, I.N. Ivanov, T. Hianik Stability monitoring of casein layer on hydrophilic SiO2 surface using quartz crystal microbalance with dissipation published pages: 178, ISSN: , DOI:	BioSensor 2017. 1st European and 10th German BioSensor Symposium March 2017	2020-04-14
2017	S. Melikishvili, Mark Dizon, B. Oâ€™Driscoll3, V. Buckin, T. Hianik Application of High-Resolution Ultrasonic Spectroscopy for real- time monitoring of trypsin activity in Î² - casein solution published pages: 16, ISSN: , DOI:	\"International workshop \"\"Recent applications of high-resolution ultrasonic spectroscopy for monitoring of hydrolytic activities in milks\"\"\" November 2017	2020-04-14
2017	R. Sarok, A. Poturnayova, K. Szabo, A. Hucker, T. Hianik Determination of aflatoxin M1 in milk and milk samples using ELISA published pages: 10, ISSN: , DOI:	\"International workshop \"\"Recent applications of high-resolution ultrasonic spectroscopy for monitoring of hydrolytic activities in milks\" November 2017	2020-04-14

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