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AMECRYS project deliverables

The page lists 9 deliverables related to the research project "AMECRYS".

 List of Deliverables

AMECRYS: list of downloadable deliverables.
title and desprition type last update

Communication events

Intermediate results of the project will be disseminated by organizing press releases and by realizing leaflets and a web video. All this material will be made available on the project website. Data coming from research activities, which will be decided to not protect by project governing bodies, will be uploaded on OpenAIRE 2020.

Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015

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Websites, patent fillings, videos etc. 2019-11-19

HEL4 domain fragment & Anti CD20 mAb process specification report

A process specification report will be prepared detailing the optimised upstream production and conventional downstream purification procedures for anti-CD20 mAb and HEL4 VH domain fragment. This will include details of the analytical methods developed to characterise the material at each of the three purity levels (post-harvest, post-capture column and final product) and the baseline quality attributes generated from these methods to allow for comparison with the crystallization process.

Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015

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Documents, reports 2019-11-19

Open-source MC-FFS computational simulation packages

The kinetic Monte Carlo codes with forward-flux sampling (and possibly other rare event techniques) used to simulate crystallization at membranes will be documented and archived on open-source repositories. The deliverable consists of the documented codes and an analysis of the results obtained for conditions corresponding to those of interest to the project.

Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015

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Other 2019-11-19

Robust microfabrication protocols to embed hydrophobic fluoropolymers membranes within microfluidic chips

Report on the development of fabrication protocols to embed the hydrophobic fluoropolymers membranes developed in WP3 within custom-made microfluidic devices obtained by standard PDMS soft lithography. These protocols may use mechanical clamping to seal the membranes between two micro-fabricated PDMS stamps or chemical linking with slight chemical modifications of the PDMS surface (preserving the requirements for mAbs crystallization).

Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015

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Documents, reports 2019-11-19

Simulation code for thermodynamics of course-grained model of mAbs in confined geometry

This will consist of DFT/MC/Molecular dynamics codes (exact methods to be decided as the work progresses) for determining the phase diagram of a coarse-grained model for mAbs. The deliverable consists of the documented codes and the resulting phase diagrams.

Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015

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Other 2019-11-19

Website and project logo

Website and project logo

Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015

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Websites, patent fillings, videos etc. 2019-11-19

Dissemination and Exploitation Plan

A dissemination and exploitation plan will be delivered defining key dissemination opportunities within the network and to academia, industry and society outside the network. The plan will describe the dissemination of results to the Project Participants, Scientific Community, Academia, and Related Industry through internal meetings, deliverables publication in Project website, presentations at relevant conferences and symposia, and by publishing results in high-impact factor peer-reviewed journals. All scientific publications will be provided as free on-line open access (green/gold model). To disseminate our project outcomes we will organize an open conference or workshop at the end of the project for which key industrial and academic researchers will be invited. The plan will also define strategies and schedule for the exploitation of project’s foregrounds.

Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015

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Documents, reports 2019-11-19

Report on preparation of nanotemplates for mAb crystallization

Report on preparation of nanotemplates of pore dimensions (3-20 nm) and characterization to determine pore dimensions and surface area. Nanotemplates will be derivitised to modify surface chemistry and characterized to confirm % of coverage.

Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015

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Documents, reports 2019-11-19

Data Management Plan

A data management plan will be constructed for the generated data in the project. This will cover data in the form of chemical synthesis protocols, models/simulations/software, design documents including drawings and specifications, construction schedules, regulatory documents, quality control and assurance records. Generated data will be preserved on the intranet platform until the end of the Project.

Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015

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Open Research Data Pilot 2019-11-19