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PHA-ST-TRAIN-VAC SIGNED

Leveraging Pharmaceutical Sciences and Structural Biology Training to develop 21st Century Vaccines

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

PHA-ST-TRAIN-VAC project word cloud

Explore the words cloud of the PHA-ST-TRAIN-VAC project. It provides you a very rough idea of what is the project "PHA-ST-TRAIN-VAC" about.

international diseases immunisation rsv university meet pha health century globally group generation 21st multidisciplinary ustrath elderly millions vaccine patient intersectoral proven gbs biology saving influenza innovative 199 sciences gsk vaccinologists syncytial respiratory born guarantee track fit hospitalisations immunomodulation engineering teams ageing 66 eliminate virus skills train leader pregnant global purpose training ing age infectious tract translatable strathclyde eid acute protect 33 tools groups immunology world st formulation pose women vac deaths pharmaceutical risk cross streptococcus biomedical entrepreneurship serious stage appropriate population invasive structural lower disease team annually expanding pharmacy infections lives equip partnership vaccines million record infants

Project "PHA-ST-TRAIN-VAC" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITY OF STRATHCLYDE Organization address address: Richmond Street 16 city: GLASGOW postcode: G1 1XQ website: www.strath.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://www.phast-train-vac.eu/
Total cost	1˙062˙698 €
EC max contribution	1˙062˙698 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2015
Funding Scheme	MSCA-ITN-EID
Starting year	2016
Duration (year-month-day)	from 2016-06-01 to 2020-05-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITY OF STRATHCLYDE UNIVERSITY OF STRATHCLYDE Organization address address: Richmond Street 16 city: GLASGOW postcode: G1 1XQ website: www.strath.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (GLASGOW)	coordinator	546˙575.00
2	GLAXOSMITHKLINE VACCINES SRL GLAXOSMITHKLINE VACCINES SRL Organization address address: VIA FIORENTINA 1 city: SIENA postcode: 53100 website: www.novartis.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (SIENA)	participant	516˙122.00

Map

Project objective

Immunisation is one of the most cost-effective and proven tools to control and eliminate infectious diseases, saving millions of lives each year, yet key challenges remain in order to guarantee the future health of the expanding and ageing global population. For example, effective vaccines are still required for Respiratory Syncytial Virus (RSV) and Group B Streptococcus (GBS), both of which cause significant hospitalisations globally each year. RSV is a common cause of respiratory disease among all age groups; annually it results in an estimated 33.8 million acute lower respiratory tract infections (resulting in 66,000-199,000 deaths) and among the elderly, it results in as many hospitalisations as influenza. Group B Streptococcus (GBS) infections also pose a serious risk; GBS is a leading cause of invasive infections in pregnant women, new-born infants, and the elderly. To meet the challenge of developing fit-for-purpose, age-appropriate vaccines against these disease targets, this EID will bring together two cross-sector, world leading teams – GSK Vaccines S.r.L and the University of Strathclyde – with the objective to equip the next generation of vaccinologists with the skills and tools to deliver vaccines for the 21st Century. GSK Vaccines S.r.L is a global leader in vaccine research, development and production and will work in partnership with the vaccine team within USTRATH and the Strathclyde Institute of Pharmacy and Biomedical Sciences, who have an international track-record of translatable and innovative research in immunology, immunomodulation, structural biology, and formulation design and pharmaceutical engineering of vaccine systems. PHA-ST-TRAIN-VAC will deliver a unique, multidisciplinary and intersectoral training programme to develop and equip four early stage researchers with the required skills and entrepreneurship to develop new vaccines to protect against RSV and GBS, in a formulation tailored to the age of the patient.

Deliverables

List of deliverables.
Identification of RSV antigen for alternative vaccination routes	Documents, reports	2020-04-08 10:20:48
Bio-distribution of adjuvants and their associated antigen - 1	Documents, reports	2020-04-08 10:20:48
Data management plan	Open Research Data Pilot	2020-04-08 10:20:48
Interactions of GBS and RSV antigen and adjuvants	Documents, reports	2020-04-08 10:20:48
Key biophysical and physico-chemical attributes of current lipid nanoparticles	Documents, reports	2020-04-08 10:20:48
Metabolic factors that contribute to the impaired adaptive immunity in older adults	Documents, reports	2020-04-08 10:20:48
Bio-distribution of lipid nanoparticles	Documents, reports	2020-04-08 10:20:47
Key physico-chemical attributes of alum, emulsion, liposome and nanoparticle systems shown to be effective as adjuvants	Documents, reports	2020-04-08 10:20:47
Model to investigate intracellular ROS, antigen presentation and specific T cell responses	Documents, reports	2020-04-08 10:20:48
Identification of self-amplifying RSV RNA construct	Documents, reports	2020-04-08 10:20:48
Comparison of cellular uptake in monocyte-derived macrophages and dendritic cells	Documents, reports	2020-04-08 10:20:48

Take a look to the deliverables list in detail: detailed list of PHA-ST-TRAIN-VAC deliverables.

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The information about "PHA-ST-TRAIN-VAC" are provided by the European Opendata Portal: CORDIS opendata.