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mR-NIPD

Proof of Concept study for ERC NIPD discovered biomarkers

Total Cost €

EC-Contrib. €

Partnership

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mR-NIPD project word cloud

Explore the words cloud of the mR-NIPD project. It provides you a very rough idea of what is the project "mR-NIPD" about.

put maternal alternative fetus generation prenatal dna mr mrna accessible proof grant sequencing erc immunoprecipitation m6a pregnant indicate 21 edward nipd seq limited chromosomal social women biomarkers bloodstream medical anticipate correlate safer pregnancy fetal merip samples transcripts independent invasive 13 trisomy status examine nipt discovered traces syndrome economic abnormalities combined patau tests 18 methylated scientific modern risk

Project "mR-NIPD" data sheet

The following table provides information about the project.

Coordinator	NIPD GENETICS PUBLIC COMPANY LIMITED Organization address address: NEAS EGKOMIS, 31 city: NICOSIA postcode: 2409 website: www.nipd.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Cyprus [CY]
Total cost	150˙000 €
EC max contribution	150˙000 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2015-PoC
Funding Scheme	ERC-POC
Starting year	2016
Duration (year-month-day)	from 2016-12-01 to 2018-05-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	NIPD GENETICS PUBLIC COMPANY LIMITED NIPD GENETICS PUBLIC COMPANY LIMITED Organization address address: NEAS EGKOMIS, 31 city: NICOSIA postcode: 2409 website: www.nipd.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CY (NICOSIA)	coordinator	150˙000.00

Map

Project objective

Scientific and medical evidence indicate that non-invasive prenatal testing, known as non-invasive prenatal testing (NIPT), is a safer alternative to invasive tests that might put the pregnancy at risk. Modern NIPT examine traces of fetal DNA in the maternal bloodstream to determine whether the fetus is at risk of chromosomal abnormalities such as, but not limited to, Down syndrome (trisomy 21), Patau syndrome (trisomy 13) and Edward’s syndrome (trisomy 18). In this ERC Proof of Concept Grant (mR-NIPD), we anticipate to correlate already discovered DNA biomarkers of the ERC NIPD (funded ERC) with biomarkers in mRNA transcripts. The method, directly related to the currently funded ERC, will use m6A-specific methylated mRNA immunoprecipitation combined with Next Generation Sequencing (MeRIP-Seq) on fetal and maternal mRNA samples. As a result, we aim to increase the number of fetal specific biomarkers and provide a novel, cost-effective non-invasive prenatal test that will be accessible to all pregnant women independent from social and economic status

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The information about "MR-NIPD" are provided by the European Opendata Portal: CORDIS opendata.