#	Pagina
attuale pagina	/open-h2020/projects/207012/index.html

Opendata, web and dolomites

PREVMETSYN

SMALL MOLECULES TO TREAT METABOLIC SYNDROME

Total Cost €

EC-Contrib. €

Partnership

Views

PREVMETSYN project word cloud

Explore the words cloud of the PREVMETSYN project. It provides you a very rough idea of what is the project "PREVMETSYN" about.

cluster protein cardiovascular accelerates glucose leads function disease dependent resistance mice cancers treat vicious hypertension obesity hyperglycemia pharmacological participates onset cells diseases mellitus powerful tools insulin ms metabolic molecules symptoms small accelerate central dyslipidemia said strategy elevated reverse certain modulate syndrome pathology diabetes alleviate inter potentially circle blood

Project "PREVMETSYN" data sheet

The following table provides information about the project.

Coordinator	MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC) Organization address address: ROBERT ROSSLE STRASSE 10 city: BERLIN postcode: 13125 website: www.mdc-berlin.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Germany [DE]
Total cost	149˙948 €
EC max contribution	149˙948 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2016-PoC
Funding Scheme	ERC-POC
Starting year	2017
Duration (year-month-day)	from 2017-01-01 to 2019-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC) MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC) Organization address address: ROBERT ROSSLE STRASSE 10 city: BERLIN postcode: 13125 website: www.mdc-berlin.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BERLIN)	coordinator	149˙948.00

Map

Project objective

SMALL MOLECULES TO TREAT METABOLIC SYNDROME Metabolic Syndrome (MS) is defined as a cluster of inter-related symptoms including central obesity, insulin resistance, dyslipidemia, and hypertension that promote the development of type 2 diabetes mellitus, cardiovascular diseases and certain cancers. In this project a pharmacological strategy will be developed that could alleviate the vicious circle of hyperglycemia (elevated blood glucose) and elevated insulin observed in metabolic syndrome that accelerates the onset of type 2 diabetes. We have identified a new protein that participates in insulin-dependent increase in glucose uptake from the blood. Loss of this protein leads to reduced insulin dependent glucose uptake and a metabolic syndrome like disease in mice. In this project small molecules that modulate the function of the said protein will be developed and evaluated. New molecules that enhance glucose uptake into cells could be potentially powerful new tools to reverse insulin resistance a key pathology of metabolic syndrome that can accelerate the onset of type 2 diabetes.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PREVMETSYN" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "PREVMETSYN" are provided by the European Opendata Portal: CORDIS opendata.