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CCHFVaccine SIGNED

Crimean-Congo Haemorrhagic Fever Vaccine

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

CCHFVaccine project word cloud

Explore the words cloud of the CCHFVaccine project. It provides you a very rough idea of what is the project "CCHFVaccine" about.

intensive vaccinology plan capacity outbreaks proven immunology haemorrhagic entities countries bsl bodies cchfever strategy vaccine models significantly crimean cchfvaccine cchfv candidates link animal virus disease validate epidemics front 4s mediated adequately infection thanks internationally competitive network gaps samples evaluation human perform natural immune protection vi appropriate background threat companies fill basis multidisciplinary fever succeed poor international attempt viral endemic put ngos congo tools countering special domestic prevention clinical advantages place health facilities edenext animals resource line global eligible cchf situation public trials functional deployment world

Project "CCHFVaccine" data sheet

The following table provides information about the project.

Coordinator	FOLKHALSOMYNDIGHETEN Organization address address: NOBELS VAG 18 city: SOLNA postcode: 171 82 website: http://folkhalsomyndigheten.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Sweden [SE]
Project website	http://www.cchfvaccine.eu/
Total cost	6˙255˙909 €
EC max contribution	5˙979˙607 € (96%)
Programme	1. H2020-EU.3.1.2. (Preventing disease)
Code Call	H2020-SC1-2016-RTD
Funding Scheme	RIA
Starting year	2017
Duration (year-month-day)	from 2017-01-01 to 2022-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	FOLKHALSOMYNDIGHETEN FOLKHALSOMYNDIGHETEN Organization address address: NOBELS VAG 18 city: SOLNA postcode: 171 82 website: http://folkhalsomyndigheten.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (SOLNA)	coordinator	1˙356˙000.00
2	KAROLINSKA INSTITUTET KAROLINSKA INSTITUTET Organization address address: Nobels Vag 5 city: STOCKHOLM postcode: 17177 website: www.ki.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (STOCKHOLM)	participant	2˙199˙576.00
3	FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT Organization address address: SUDUFER 10 city: GREIFSWALD-INSEL RIEMS postcode: 17493 website: www.fli.bund.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (GREIFSWALD-INSEL RIEMS)	participant	505˙000.00
4	INSERM - TRANSFERT SA INSERM - TRANSFERT SA Organization address address: RUE WATT 7 city: PARIS postcode: 75013 website: www.inserm-transfert.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	351˙875.00
5	JUSTUS-LIEBIG-UNIVERSITAET GIESSEN JUSTUS-LIEBIG-UNIVERSITAET GIESSEN Organization address address: LUDWIGSTRASSE 23 city: GIESSEN postcode: 35390 website: www.uni-giessen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (GIESSEN)	participant	348˙281.00
6	Department of Health Department of Health Organization address address: Quarry House, Quarry Hill city: Leeds postcode: LS2 7UE website: www.dh.gov.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (Leeds)	participant	348˙000.00
7	STATENS VETERINAERMEDICINSKA ANSTALT STATENS VETERINAERMEDICINSKA ANSTALT Organization address address: Ulls Vaeg 2B city: UPPSALA postcode: 75189 website: http://www.sva.se/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (UPPSALA)	participant	240˙250.00
8	SIVAS CUMHURIYET UNIVERSITESI SIVAS CUMHURIYET UNIVERSITESI Organization address address: KAYSERI CADDESI city: SIVAS postcode: 58140 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	TR (SIVAS)	participant	140˙250.00
9	BUNDESINSTITUT FUR IMPFSTOFFE UND BIOMEDIZINISCHE ARZNEIMITTEL BUNDESINSTITUT FUR IMPFSTOFFE UND BIOMEDIZINISCHE ARZNEIMITTEL Organization address address: PAUL-EHRLICH-STRASSE 51-59 city: LANGEN postcode: 63225 website: www.pei.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (LANGEN)	participant	136˙000.00
10	KAFKAS UNIVERSITESI KAFKAS UNIVERSITESI Organization address address: PASACAYIRI city: KARS postcode: 36100 website: www.kafkas.edu.tr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	TR (KARS)	participant	134˙375.00
11	NATIONAL CENTER OF INFECTIOUS AND PARASITIC DISEASES NATIONAL CENTER OF INFECTIOUS AND PARASITIC DISEASES Organization address address: blvd. Yanko Sakazov 26 city: SOFIA postcode: 1504 website: www.ncipd.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BG (SOFIA)	participant	80˙000.00
12	TAJIK RESEARCH INSTITUTE OF PREVENTIVE MEDICINE TAJIK RESEARCH INSTITUTE OF PREVENTIVE MEDICINE Organization address address: 61 SHEVCHENKO STR city: DUSHANBE postcode: 734025 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	TJ (DUSHANBE)	participant	80˙000.00
13	MINISTRIA E SHENDETESISE MINISTRIA E SHENDETESISE Organization address address: ZAGREB STREET city: PRISTINA postcode: 10000 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	XK (PRISTINA)	participant	60˙000.00

Map

Project objective

Natural epidemics and outbreaks of emerging viral epidemics are growing problems internationally. The general aim of the CCHFVaccine project is to develop and deliver a vaccine, which can significantly increase our capacity to control the situation of Crimean Congo Haemorrhagic fever (CCHF) disease on a global basis. The proposed work program on CCHF virus aims to build a multidisciplinary research network, able to deliver vaccine candidates, methods and procedures eligible for clinical trials, with a special focus on prevention. Thanks to the background, unique facilities and tools available among the consortium participants, CCHFVaccine will deliver tools for countering the threat of this infection in Europe and endemic areas of the world. This work program will attempt to fill gaps in CCHFV virus research on immunology and vaccinology. To achieve this overall aim, an intensive work plan will be put in place with the following specific objectives: i) to produce vaccine candidates, ii) to bring several unique animal models into front line vaccine research, iii) to validate and bring the most promising vaccine candidates to clinical trials, iv) to ensure that an immune mediated protection is adequately understood, v) to perform clinical trials at Phase I and ensure a strategy for the effective deployment and utilization in resource-poor countries, and vi) to link this project to public health bodies, NGOs and vaccine companies. The proposed CCHFVaccine project will succeed in bringing together selected competitive advantages such as: operating capacity with appropriate facilities (state-of-the-art BSL-4s) and the only animal BSL-4 -with capacity to challenge domestic animals in Europe, highly experienced researchers in the development and evaluation of vaccine candidates, authorities and entities of human and animal health, clinical samples from endemic countries, and an international network proven to be functional by the previous EU-funded CCHFever and EDENext.

Publications

List of publications.
year	authors and title	journal	last update
2018	Jessica R. Spengler, Dennis A. Bente, Mike Bray, Felicity Burt, Roger Hewson, GÃ¼lay Korukluoglu, Ali Mirazimi, Friedemann Weber, Anna Papa Second International Conference on Crimean-Congo Hemorrhagic Fever published pages: 137-147, ISSN: 0166-3542, DOI: 10.1016/j.antiviral.2017.11.019	Antiviral Research 150	2020-03-11
2018	Amanda Fritzen, Christian Risinger, Gulay Korukluoglu, Iva Christova, Arina Corli Hitzeroth, Natalie Viljoen, Felicity Jane Burt, Ali Mirazimi, Ola Blixt Epitope-mapping of the glycoprotein from Crimean-Congo hemorrhagic fever virus using a microarray approach published pages: e0006598, ISSN: 1935-2735, DOI: 10.1371/journal.pntd.0006598	PLOS Neglected Tropical Diseases 12/7	2020-03-11
2017	Jorma Hinkula, StÃ©phanie Devignot, Sara Ã…kerstrÃ¶m, Helen Karlberg, Eva Wattrang, SÃ¡ndor Bereczky, Mehrdad Mousavi-Jazi, Christian Risinger, Gunnel Lindegren, Caroline Vernersson, Janusz Paweska, Petrus Jansen van Vuren, Ola Blixt, Alejandro Brun, Friedemann Weber, Ali Mirazimi Immunization with DNA Plasmids Coding for Crimean-Congo Hemorrhagic Fever Virus Capsid and Envelope Proteins and/or Virus-Like Particles Induces Protection and Survival in Challenged Mice published pages: , ISSN: 0022-538X, DOI: 10.1128/JVI.02076-16	Journal of Virology 91/10	2020-03-11

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The information about "CCHFVACCINE" are provided by the European Opendata Portal: CORDIS opendata.