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AS-CELLEXPAND SIGNED

Role of alternative splicing in cell expansion and plant growth

Total Cost €

EC-Contrib. €

Partnership

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AS-CELLEXPAND project word cloud

Explore the words cloud of the AS-CELLEXPAND project. It provides you a very rough idea of what is the project "AS-CELLEXPAND" about.

expression gene sr abnormal abiotic multiple biosynthetic plant cues mrnas mediated arginine regulation encoding generates proteins cells serine developmental expand function modulate sr45 biosynthesis transcriptional cell remodeling stress mechanisms morphogenic regulator composition posttranscriptional genes impacts regulators alternative little events markedly normal wall splicing walls capacity binds mutations transcripts protein structural architecture correctly environmental

Project "AS-CELLEXPAND" data sheet

The following table provides information about the project.

Coordinator	FUNDACAO CALOUSTE GULBENKIAN Organization address address: AVENIDA BERNA 45 city: LISBOA postcode: 1000 website: www.igc.gulbenkian.pt contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Portugal [PT]
Total cost	148˙635 €
EC max contribution	148˙635 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2016
Funding Scheme	MSCA-IF-EF-ST
Starting year	2018
Duration (year-month-day)	from 2018-09-01 to 2020-08-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	FUNDACAO CALOUSTE GULBENKIAN FUNDACAO CALOUSTE GULBENKIAN Organization address address: AVENIDA BERNA 45 city: LISBOA postcode: 1000 website: www.igc.gulbenkian.pt contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PT (LISBOA)	coordinator	148˙635.00

Map

Project objective

Plant growth and morphogenic changes in response to developmental and environmental cues depend on the capacity of cells to expand correctly, which requires structural remodeling of cell walls. Importantly, abiotic stress markedly impacts plant growth by affecting many aspects related to the cell wall, from its composition to the expression of biosynthetic and remodeling genes. The importance of transcriptional regulation of genes controlling cell wall biosynthesis and architecture in response to environmental cues is well studied, but little is known about posttranscriptional mechanisms that affect their function. SR (serine/arginine-rich) proteins are major regulators of alternative splicing (AS), which generates multiple transcripts from the same gene and may modulate plant stress responses. Given evidence that (i) abiotic stress affects SR protein function; (ii) mutations in SR genes cause abnormal plant growth; and (iii) SR45 directly binds mRNAs encoding cell wall regulators, this project will investigate a role for SR-mediated regulation of AS events in cell wall regulators during plant development and abiotic stress responses. Specific objectives are to: (i) identify AS events in cell wall regulator genes that may impact plant growth; (ii) study their regulation by SR proteins; and (iii) assess whether they determine normal plant growth under environmental stress.

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The information about "AS-CELLEXPAND" are provided by the European Opendata Portal: CORDIS opendata.