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DIFFER SIGNED

Determinants of genetic diversity: Important Factors For Ecosystem Resilience

Total Cost €

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EC-Contrib. €

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Partnership

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 DIFFER project word cloud

Explore the words cloud of the DIFFER project. It provides you a very rough idea of what is the project "DIFFER" about.

linked    fishes    poorly    reference    organismal    empirically    genomic    examine    hybridization    underwater    interplay    african    speciation    unknown    instead    traits    rate    cichlid    east    edge    massive    proxy    photographs    framework    evolution    relative    population    life    resilience    alterations    time    amount    endemic    variation    recombination    determinants    me    200    estimating    contrasting    thoroughly    populations    diversity    owing    dataset    contributions    cutting    basis    suitable    census    ideal    species    sizes    trio    family    maps    techniques    differ    assemblies    read    environmental    always    ecosystem    individuals    connected    model    genetic    reflected    combining    sequencing    lake    mutation    pivotal    rates    size    fish    evaluation    history    tanganyika    radiation    morphological    behavioral    ecological   

Project "DIFFER" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITAT BASEL    more Organization address address: PETERSPLATZ 1 city: BASEL postcode: 4051 website: www.unibas.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Switzerland [CH]
Total cost	304˙724 €
EC max contribution	304˙724 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2019
Funding Scheme	MSCA-IF-EF-CAR
Starting year	2020
Duration (year-month-day)	from 2020-10-01   to  2023-09-30

 Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITAT BASEL × UNIVERSITAT BASEL Organization address address: PETERSPLATZ 1 city: BASEL postcode: 4051 website: www.unibas.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a. Close	CH (BASEL)	coordinator	304˙724.00

Map

 Project objective

Genetic diversity – that is, the genomic variation among individuals of a given species – is pivotal for adaptation to environmental alterations and an important factor for ecosystem resilience. Yet, the determinants of genetic diversity remain poorly understood. Population size is often used as a proxy for genetic diversity, but the amount of genetic variation within populations is not always reflected by their population size. Instead, factors such as linked selection, the recombination-, mutation-, and speciation rate, or life history and ecological traits may be more strongly connected to genetic diversity. So far, the interplay of all these parameters has not been empirically investigated, so that their relative contributions to genetic diversity are unknown. In DIFFER!, I propose to thoroughly examine the role of all these potential determinants of genetic diversity by means of combining cutting-edge genomic techniques with a highly suitable model system: the more than 200 endemic cichlid fish species of the East African Lake Tanganyika. Owing to their great morphological and behavioral variation, contrasting speciation rates, and their recent radiation, these fishes offer an ideal framework for comparative analyses. Availability of long-read reference assemblies, recombination maps, a massive dataset of underwater photographs for estimating census population sizes, together with population sequencing of selected species and family-based ‘trio’ sequencing will enable me to investigate specifically the interplay between genetic diversity and (i) life history and ecological traits, (ii) speciation and hybridization rates, and (iii) mutation rates, while at the same time controlling for variation in population size, selection, and recombination. The results of this project will contribute towards the understanding of organismal evolution and provide a new basis for the evaluation of genetic diversity in ecosystem management.

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The information about "DIFFER" are provided by the European Opendata Portal: CORDIS opendata.

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