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META-CAN SIGNED

Targeting the metabolism-immune system connections in Cancer

Total Cost €

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EC-Contrib. €

0

Partnership

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Project "META-CAN" data sheet

The following table provides information about the project.

Coordinator
FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE 

Organization address
address: AVENIDA GRAN VIA HOSPITALET 199-203
city: L'HOSPITALET DE LLOBREGAT
postcode: 8908
website: www.idibell.cat

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website https://www.metacan.eu/
 Total cost 3˙831˙957 €
 EC max contribution 3˙831˙957 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2017
 Funding Scheme MSCA-ITN-ETN
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2021-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE ES (L'HOSPITALET DE LLOBREGAT) coordinator 743˙618.00
2    INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE FR (PARIS) participant 525˙751.00
3    MEDIZINISCHE UNIVERSITAET WIEN AT (WIEN) participant 511˙868.00
4    VIB VZW BE (ZWIJNAARDE - GENT) participant 501˙120.00
5    TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD IL (HAIFA) participant 455˙525.00
6    EVOTEC (FRANCE) SAS FR (TOULOUSE CEDEX) participant 262˙875.00
7    UNIVERSITE PARIS DESCARTES FR (PARIS CEDEX 06) participant 262˙875.00
8    AMC MEDICAL RESEARCH BV NL (AMSTERDAM ZUIDOOST) participant 255˙374.00
9    APPLIED RESEARCH USING OMIC SCIENCES SL ES (CORNELLA) participant 247˙872.00
10    IBM ISRAEL - SCIENCE AND TECHNOLOGY LTD IL (PETACH TIKVA) participant 65˙075.00
11    ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) participant 0.00
12    ASSISTANCE PUBLIQUE HOPITAUX DE PARIS FR (PARIS) participant 0.00
13    TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY IL (HAIFA) participant 0.00
14    BIOcomuniCAT ES (Barcelona) partner 0.00
15    BOEHRINGER INGELHEIM RCV GMBH & CO KG AT (WIEN) partner 0.00
16    Canceropole PACA FR (Marseille) partner 0.00
17    FUNDACION ESADE ES (BARCELONA) partner 0.00
18    HOSPITAL SANT JOAN DE DÉU ES (ESPLUGUES DE LLOBREGAT) partner 0.00
19    Seahorse Bio (Agilent Technologies) US (North Billerica) partner 0.00
20    The FEBS Journal (FEBS) UK (Cambridge) partner 0.00

Map

 Project objective

'Cancer cells show common features of profound metabolic changes and escape from the immune system, independently of their tissue of origin. These metabolic adaptations are not limited to glucose metabolism (the 'Warburg effect') but are more general and affect several metabolic pathways in cancer cells as well as in the stroma, including immune cells. This network will explore how nutrients and hypoxia regulate the tumor-immune system interplay, and how this communication is controlled by oncogenes, metabolic regulators and current or potential drugs targeting metabolism. Understanding how metabolism can affect tumor cells and the anti-cancer immune response represents a potential therapeutic intervention point that can be exploited to develop novel therapies and new diagnostic and prognostic markers. The development of therapies targeting cancer metabolism is hampered by: 1) the complexity of the regulation that metabolism exerts on many different tumor layers, which requires multidisciplinary collaborations, and 2) the shortage of scientists that can navigate with ease between academic, industrial and clinical sectors and have the scientific and complementary skills to convert research findings into commercial and clinical applications. This network provides a pan-European interdisciplinary and intersectoral training program of excellence bringing young researchers together with World leading academics, clinicians, pharma industry members, corporate research and dissemination and outreach specialists. As part of the research training, the consortium will conduct a coherent and integrated set of hypothesis-driven research projects that are aimed at discovering, describing and exploiting how metabolism at the cell and the whole body levels is integrated with modulation of cell death susceptibility and the immune response in the context of cancer. '

 Deliverables

List of deliverables.
First Scientific Training Other 2020-01-14 14:33:10
Second Scientific Training Other 2020-01-14 14:33:07
Website Websites, patent fillings, videos etc. 2020-01-14 14:33:11
Second complementary skills training Other 2020-01-14 14:33:14
First Complementary skills training Other 2020-01-14 14:33:10
ESR recruitment start Other 2020-01-14 14:33:13
Social Media accounts Websites, patent fillings, videos etc. 2020-01-14 14:33:08

Take a look to the deliverables list in detail:  detailed list of META-CAN deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Paweł Bieniasz-Krzywiec, Rosa Martín-Pérez, Manuel Ehling, Melissa García-Caballero, Sotiria Pinioti, Samantha Pretto, Roel Kroes, Chiara Aldeni, Mario Di Matteo, Hans Prenen, María Virginia Tribulatti, Oscar Campetella, Ann Smeets, Agnes Noel, Giuseppe Floris, Jo A. Van Ginderachter, Massimiliano Mazzone
Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer
published pages: , ISSN: 1550-4131, DOI: 10.1016/j.cmet.2019.07.015
Cell Metabolism 2019-10-08
2019 Adam Spiro, Jonatan Fernández García, Chen Yanover
Inferring new relations between medical entities using literature curated term co-occurrences
published pages: , ISSN: 2574-2531, DOI: 10.1093/jamiaopen/ooz022
JAMIA Open 2019-09-02
2019 Johanna Chiche, Julie Reverso-Meinietti, Annabelle Mouchotte, Camila Rubio-Patiño, Rana Mhaidly, Elodie Villa, Jozef P. Bossowski, Emma Proics, Manuel Grima-Reyes, Agnès Paquet, Konstantina Fragaki, Sandrine Marchetti, Josette Briere, Damien Ambrosetti, Jean-François Michiels, Thierry Jo Molina, Christiane Copie-Bergman, Jacqueline Lehmann-Che, Isabelle Peyrottes, Frederic Peyrade, Eric de Kerviler, Bruno Taillan, Georges Garnier, Els Verhoeyen, Véronique Paquis-Flucklinger, Laetitia Shintu, Vincent Delwail, Celine Delpech-Debiais, Richard Delarue, André Bosly, Tony Petrella, Gabriel Brisou, Bertrand Nadel, Pascal Barbry, Nicolas Mounier, Catherine Thieblemont, Jean-Ehrland Ricci
GAPDH Expression Predicts the Response to R-CHOP, the Tumor Metabolic Status, and the Response of DLBCL Patients to Metabolic Inhibitors
published pages: , ISSN: 1550-4131, DOI: 10.1016/j.cmet.2019.02.002
Cell Metabolism 2019-07-08

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The information about "META-CAN" are provided by the European Opendata Portal: CORDIS opendata.

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