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ENVIROSTOME SIGNED

Exploring the contribution of bacteriophages to the emergence and spread of antibiotic resistance in environmental settings

Total Cost €

EC-Contrib. €

Partnership

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ENVIROSTOME project word cloud

Explore the words cloud of the ENVIROSTOME project. It provides you a very rough idea of what is the project "ENVIROSTOME" about.

plant overlooked conventional settings runoff warrants agricultural intelligence world resistance continually clinical emergence bluetech diversity contain aacute health antibiotic public metabolites horizontal exposed disturbances tackling secondment company extensively insights intersectoral ceo consequence class mixing contribution hypothesis selective environment founder callaghan exchange crisis feeding exogenous genes bacteriophages variety acquisition water args play aquatic prevalence phenomenon anthropogenic animal demonstrated group balcaz antimicrobials clarify critical wastewater sources explored discharges phages paul global disinfection ecological environmental environments transfer dr treatment arg maintenance provides envirostome resistant operations bacteria ideal spread

Project "ENVIROSTOME" data sheet

The following table provides information about the project.

Coordinator	FUNDACIO INSTITUT CATALA DE RECERCA DE L'AIGUA Organization address address: CALLE EMILI GRAHIT EDIFICI H20 101 city: GIRONA postcode: 17003 website: http://icra.udg.cat contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Total cost	170˙121 €
EC max contribution	170˙121 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2017
Funding Scheme	MSCA-IF-EF-CAR
Starting year	2019
Duration (year-month-day)	from 2019-04-01 to 2021-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	FUNDACIO INSTITUT CATALA DE RECERCA DE L'AIGUA FUNDACIO INSTITUT CATALA DE RECERCA DE L'AIGUA Organization address address: CALLE EMILI GRAHIT EDIFICI H20 101 city: GIRONA postcode: 17003 website: http://icra.udg.cat contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (GIRONA)	coordinator	170˙121.00

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Project objective

Antibiotic resistance has become a global public health concern. Although this phenomenon has been widely studied in clinical settings, its impact has not been extensively explored in environmental settings. The environment is continually exposed to a wide variety of antimicrobials and their metabolites through wastewater treatment plant discharges, agricultural runoff, and animal feeding operations which may contribute to the emergence and spread of antibiotic resistance. Moreover, the large-scale mixing of environmental bacteria with exogenous bacteria from anthropogenic sources provides the ideal selective and ecological conditions for the emergence of resistant bacteria. As a consequence, aquatic environments may provide ideal settings for the horizontal exchange of antibiotic resistance genes. Our working hypothesis is that bacteriophages (phages) play an important (and overlooked) role in the acquisition, maintenance and spread of antibiotic resistance genes (ARGs) in environmental settings, particularly under anthropogenic disturbances. The specific aims of the ENVIROSTOME project are (i) to determine the contribution of phages to the horizontal transfer of ARGs in aquatic environments, and (ii) to investigate the impact of conventional and novel disinfection approaches in wastewater treatment on the prevalence of ARG-carrying phages in aquatic environments. Dr. Balcazár’s group have demonstrated that environmental phages contain a large diversity of ARGs, which warrants further research to clarify their contribution to the emergence of antibiotic resistance among environmental bacteria, as well as to investigate their control through disinfection. The results of this research are expected to deliver critical insights for tackling the global crisis of antibiotic resistance. The project is also supported by an intersectoral secondment with the world-class water intelligence company BlueTech Research and by its founder and CEO, Paul O'Callaghan.

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The information about "ENVIROSTOME" are provided by the European Opendata Portal: CORDIS opendata.