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aDDRess SIGNED

Joint Training and Research Program on Chromatin Dynamics and the DNA Damage Response

Total Cost €

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EC-Contrib. €

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Partnership

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 aDDRess project word cloud

Explore the words cloud of the aDDRess project. It provides you a very rough idea of what is the project "aDDRess" about.

architecture    developmental    relevance    abnormalities    genome    requiring    intact    disease    grounds    carefully    transmitted    smes    direct    onset    functional    genes    onto    training    excellence    vital    intellectual    basic    cancer    threatening    socioeconomic    nucleosome    translational    cellular    scientific    dna    activation    durable    defects    health    rna    series    stronger    cells    network    life    basis    damage    metabolic    faithfully    neurodegeneration    labs    chromatin    transform    transcription    integrating    participating    multidisciplinary    causal    esrs    discoveries    individual    biogenesis    reprogramming    progeny    links    designed    successful    trigger    prospects    mechanisms    remodeling    syndrome    biological    additional    play    create    rare    shed    employment    ranging    devastating    sophisticated    repair    careers    counteract    instability    premature    paths    battery    action    diseases    complications    reveals    quality    functionally    human    light    age    independent    pushed    collaborations    industry    platform    roles    maintenance   

Project "aDDRess" data sheet

The following table provides information about the project.

Coordinator
IDRYMA TECHNOLOGIAS KAI EREVNAS 

Organization address
address: N PLASTIRA STR 100
city: IRAKLEIO
postcode: 70013
website: www.forth.gr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Greece [EL]
 Total cost 4˙011˙939 €
 EC max contribution 4˙011˙939 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2018
 Funding Scheme MSCA-ITN-ETN
 Starting year 2019
 Duration (year-month-day) from 2019-03-01   to  2023-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IDRYMA TECHNOLOGIAS KAI EREVNAS EL (IRAKLEIO) coordinator 486˙035.00
2    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) participant 297˙522.00
3    NORGENOTECH AS NO (OSLO) participant 292˙342.00
4    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 281˙982.00
5    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE CH (LAUSANNE) participant 281˙276.00
6    GENEVIA TECHNOLOGIES OY FI (TAMPERE) participant 280˙805.00
7    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) participant 274˙802.00
8    LXREPAIR FR (LA TRONCHE) participant 274˙802.00
9    UNIVERSITE DE PARIS FR (PARIS) participant 274˙802.00
10    STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS NL (AMSTERDAM) participant 265˙619.00
11    IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE IT (MILANO) participant 261˙499.00
12    KLINIKUM DER UNIVERSITAET ZU KOELN DE (KOELN) participant 252˙788.00
13    LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN DE (MUENCHEN) participant 252˙788.00
14    FAKULTNI NEMOCNICE U SV. ANNY V BRNE CZ (Brno) participant 234˙871.00
15    UNIVERSITE PARIS DIDEROT - PARIS 7 FR (PARIS) participant 0.00
16    ETAIRIA DIACHIRISIS KAI ANAPTIXIS EPISTIMONIKOU KAI TECHNOLOGIKOU PARKOU KRITIS AE EL (HERAKLION) partner 0.00
17    PANEPISTIMIO KRITIS EL (RETHIMNO) partner 0.00
18    SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE IT (TRIESTE) partner 0.00
19    UNIVERSITAET ZU KOELN DE (KOELN) partner 0.00
20    UNIVERSITE DE GENEVE CH (GENEVE) partner 0.00

Map

 Project objective

Defects in DNA repair trigger a number of devastating health complications ranging from developmental abnormalities to the premature onset of age-related diseases, including the metabolic syndrome, neurodegeneration and cancer. To counteract genome instability, cells have evolved a battery of DNA repair mechanisms ensuring that their genome remains functionally intact and is faithfully transmitted to progeny. Recent work reveals that DNA repair factors play additional roles in vital biological processes, including nucleosome remodeling, chromatin architecture, RNA biogenesis or the transcription activation of genes involved in cellular reprogramming and growth. These recent discoveries have pushed the DNA repair field forward and towards new grounds requiring a series of sophisticated functional and multidisciplinary approaches. Based on these novel scientific paths, we have carefully designed the “aDDRess” consortium on the basis of past excellence of the individual participants and their relevance to the proposed field. The action addresses a major research topic i.e. DNA damage in development and disease with great socioeconomic impact in Europe and direct relevance to human health. The objectives of the program are: i. to create a European research platform of excellence in the field of DNA repair by integrating research from basic mechanisms to translational research applications, ii. to establish a Network dedicated to the high-quality training of ESRs promoting their independent careers and future employment prospects, iii. to transform our current successful, long-term collaborations into a stronger intellectual network and build durable links between the participating labs and the industry (SMEs). Understanding the relevance of genome maintenance pathways to human health will shed light onto the causal mechanisms of rare and widespread life-threatening diseases, including cancer.

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