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ARREST-TB SIGNED

Accurate, Rapid, Robust and Economical diagnostic technoliogieS for Tuberculosis

Total Cost €

EC-Contrib. €

Partnership

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ARREST-TB project word cloud

Explore the words cloud of the ARREST-TB project. It provides you a very rough idea of what is the project "ARREST-TB" about.

local risk diagnosis running small mycobacterium thereby facilities infection removing centralised economically detection point optical replacing clinicians negligible portable notification probes surveillance remote affordable resistant assays cloud tb constraints molecular resistance biomarkers microscopy wash minimal practical health core accurate modulated mycobacteria world tuberculosis interventions vision profiles tests diagnostics resourcing settings training progression care latent assessing coupled micrornas initial rapid hours visionary patients blood telemetry active triage stated sputum screening groups samples chemical context identification lower public quantification resource primary treatment expertise drug technologies mins imposition poor

Project "ARREST-TB" data sheet

The following table provides information about the project.

Coordinator	THE UNIVERSITY OF EDINBURGH Organization address address: OLD COLLEGE, SOUTH BRIDGE city: EDINBURGH postcode: EH8 9YL website: www.ed.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Total cost	4˙438˙898 €
EC max contribution	2˙997˙496 € (68%)
Programme	1. H2020-EU.3.1.1. (Understanding health, wellbeing and disease)
Code Call	H2020-SC1-2018-Single-Stage-RTD
Funding Scheme	RIA
Starting year	2019
Duration (year-month-day)	from 2019-01-01 to 2020-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE UNIVERSITY OF EDINBURGH THE UNIVERSITY OF EDINBURGH Organization address address: OLD COLLEGE, SOUTH BRIDGE city: EDINBURGH postcode: EH8 9YL website: www.ed.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (EDINBURGH)	coordinator	1˙031˙682.00
2	HERIOT-WATT UNIVERSITY HERIOT-WATT UNIVERSITY Organization address address: Riccarton city: EDINBURGH postcode: EH14 4AS website: www.hw.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (EDINBURGH)	participant	592˙452.00
3	DESTINA GENOMICA DESTINA GENOMICA Organization address address: AVENIDA DE LA INNOACI0N 1 city: GRANADA postcode: 18100 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (GRANADA)	participant	417˙911.00
4	UNIVERSITA DEGLI STUDI DI PADOVA UNIVERSITA DEGLI STUDI DI PADOVA Organization address address: VIA 8 FEBBRAIO 2 city: PADOVA postcode: 35122 website: www.unipd.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (PADOVA)	participant	391˙750.00
5	GENETIC ANALYSIS STRATEGIES SL GENETIC ANALYSIS STRATEGIES SL Organization address address: CALLE SANTA JUSTA 5 6 B city: ORIHUELA ALICANTE postcode: 3300 website: www.geneticpcr.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (ORIHUELA ALICANTE)	participant	292˙450.00
6	OPTOELETTRONICA ITALIA SRL OPTOELETTRONICA ITALIA SRL Organization address address: VIA VIENNA 8 city: TRENTO postcode: 38121 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (TRENTO)	participant	271˙250.00
7	CENTRAL TUBERCULOSIS RESEARCH INSTITUTE OF RUSSIAN ACADEMY OF MEDICAL SCIENCES CENTRAL TUBERCULOSIS RESEARCH INSTITUTE OF RUSSIAN ACADEMY OF MEDICAL SCIENCES Organization address address: Yauzskay alley 2 city: Moscow postcode: 107564 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	RU (Moscow)	participant	0.00
8	INDIAN COUNCIL OF MEDICAL RESEARCHSOCIETY INDIAN COUNCIL OF MEDICAL RESEARCHSOCIETY Organization address address: ANSARI NAGAR city: NEW DELHI postcode: 110029 website: www.icmr.nic.in contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IN (NEW DELHI)	participant	0.00
9	SHANMUKHA INNOVATIONS PRIVATE LIMITED SHANMUKHA INNOVATIONS PRIVATE LIMITED Organization address address: KAGGADASAPURA 101 KK TOWERS BALAJI LAYOUT CV RAMAN NAGAR city: BENGALURU postcode: 560093 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IN (BENGALURU)	participant	0.00

Map

Project objective

This visionary project addresses the key needs of patients, clinicians and the World Health Organisations stated deliverables of affordable, reliable and point-of-care molecular TB diagnostics, with the vision of removing the need for centralised facilities and offering remote primary care diagnosis coupled with telemetry for “cloud based” notification to ensure public health and surveillance interventions. The core technology deliverables will include: Rapid screening of TB infection (within 30 mins): We will develop low-cost portable optical devices and chemical molecular probes for accurate and rapid ‘triage tests’ to allow ‘no-wash’ detection of Mycobacteria ‘in-field’ in sputum at costs comparable with or lower than existing microscopy-based methods. This technology has the aim of replacing current sputum-based microscopy methods. Rapid molecular identification of drug resistance (within 2 hours): We will develop novel low-cost assays based on molecular methods that will allow accurate and rapid screening for the Mycobacterium tuberculosis complex in sputum and drug-resistant tuberculosis, thus providing rapid screening of at risk groups for TB as well as identification of drug resistance profiles. Biomarkers for early diagnosis and assessing treatment response: A higher risk element is the development of point-of-care diagnostics for quantification of microRNAs (that are known to be modulated during progression from latent to active TB and during treatment progression), directly from small blood samples. We will ensure that the technologies are economically viable in the context of resource poor settings – indeed the whole project will be driven by practical need and local resourcing constraints – NOT imposition. Thus it will require negligible initial costs for implementation, minimal training and expertise, with the running costs less than 1/10 th of current detection technologies, thereby addressing a key objective of the work program.

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The information about "ARREST-TB" are provided by the European Opendata Portal: CORDIS opendata.