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ERMADA SIGNED
Illuminating Earth’s microbial diversity and origins from metagenomes with deep learning
Total Cost €
0EC-Contrib. €
0Partnership
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0ERMADA project word cloud
Explore the words cloud of the ERMADA project. It provides you a very rough idea of what is the project "ERMADA" about.
govern
prevalent
sequences
models
effort
sequencing
abstract
represented
latter
uncover
environments
patterns
reference
microorganisms
levels
similarity
exceeds
elucidate
nutrient
origins
rank
cutting
terabytes
sequence
trained
bioinformatics
staggering
edge
big
footprint
networks
planet
employ
10
pertaining
serve
composition
microbes
volumes
outnumbers
metagenomic
cycles
taxonomically
99
learning
evolution
terrestrial
neural
microbial
network
capture
5
painstaking
biodiversity
community
hundreds
dataset
samples
galaxy
record
complete
12
twofold
circulation
climate
genome
whereas
conventional
microbiome
gain
data
marine
animals
stars
species
enzymes
cultured
functions
lineages
metabolic
biomass
milky
4
environmental
unknown
genes
plants
earth
capacities
deep
shotgun
diversity
algorithms
uncharacterized
roles
classifying
structure
classified
deeper
machine
regulating
play
habitats
biogeochemical
analyze
emerged
classify
Project "ERMADA" data sheet
The following table provides information about the project.
| Coordinator |
BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING
Organization address contact info |
| Coordinator Country | Greece [EL] |
| Total cost | 247˙628 € |
| EC max contribution | 247˙628 € (100%) |
| Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
| Code Call | H2020-MSCA-IF-2018 |
| Funding Scheme | MSCA-IF-EF-CAR |
| Starting year | 2019 |
| Duration (year-month-day) | from 2019-08-01 to 2023-03-09 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING | EL (VARI-ATHENS) | coordinator | 247˙628.00 |
Map
Project objective
The estimated number of microbes on our planet outnumbers the stars of the Milky Way galaxy and their biomass exceeds that of all plants and animals. Out of the 10^12 microbial species, only around 10^4 have been cultured, less than 10^5 species are represented by classified sequences, and a staggering estimated 99% of these microorganisms remain taxonomically unknown. Metagenomic shotgun sequencing has emerged as the most prevalent way of studying and classifying microorganisms from various habitats whereas genome analysis can be used to uncover the functions of genes, enzymes and metabolic pathways in a microbial community. This painstaking effort is crucial to understanding Earth's biodiversity, as microbes play important roles in regulating the planet’s biogeochemical cycles through processes that govern nutrient circulation in both terrestrial and marine environments. In this proposal, we will employ cutting edge bioinformatics and machine learning algorithms to analyze and elucidate Earth’s microbial diversity. We will use deep neural networks trained by large volumes of metagenomic sequences as well as big data methods to process hundreds of terabytes of data and taxonomically classify all uncharacterized metagenomic samples, by identifying their origins and habitats. Going beyond the capacities of conventional sequence similarity and comparison analyses, neural network models can capture higher level, abstract defining features and patterns in metagenomic sequences. The aim of this study is twofold: i) to gain a deeper understanding of the composition and structure of the microbiome at different rank levels and lineages and ii) to provide a complete record of the planet’s present microbial diversity footprint. The latter can serve as a reference dataset for future studies pertaining to microbiome evolution due to climate change or other long-term environmental factors.
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No valid XML
lastchecktime (2024-05-11 9:59:17) correctly updated