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SBR SIGNED

SMART BONE REGENERATION

Total Cost €

0

EC-Contrib. €

0

Partnership

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 SBR project word cloud

Explore the words cloud of the SBR project. It provides you a very rough idea of what is the project "SBR" about.

treatment    scope    model    inflammation    identification    explore    chain    preclinical    monitoring    vivo    medical    ideal    suffer    vitro    strategies    ph    fibers    proof    infection    introduces    conventional    strategy    enriched    performance    customized    particulate    sensors    3d    vital    injury    compatibility    sbr    parts    specifications    embedding    patient    regulatory    animal    mechanical    regenerative    printed    population    healthcare    physiology    aged    adjustement    defects    conductive    smart    pathology    commercialization    biocompatible    inks    placement    implant    stem    suitable    temperature    bone    electronic    inspired    allografts    of    polymers    embed    global    programming    engineering    resorbable    limited    tested    fast    communication    proper    agents    solution    scaffold    adjustable    elaborated    restoration    tissue    reconstruction    grade    gender    innovative    efficacy    characterization    srb    cells    immunorejection    pressure    clinical    bioactive    minimal    autografts    electrospun   

Project "SBR" data sheet

The following table provides information about the project.

Coordinator
PANEPISTIMIO PATRON 

Organization address
address: UNIVERSITY CAMPUS RIO PATRAS
city: RIO PATRAS
postcode: 265 04
website: www.upatras.gr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Greece [EL]
 Total cost 6˙379˙337 €
 EC max contribution 6˙379˙337 € (100%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SC1-2019-Single-Stage-RTD
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2023-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    PANEPISTIMIO PATRON EL (RIO PATRAS) coordinator 779˙318.00
2    CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT CH (NEUCHATEL) participant 989˙945.00
3    ACONDICIONAMIENTO TARRASENSE ASSOCIACION ES (TERRASSA) participant 854˙335.00
4    GENES'INK FR (ROUSSET) participant 740˙062.00
5    KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN DE (MUENCHEN) participant 643˙125.00
6    RESCOLL FR (PESSAC) participant 581˙193.00
7    EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH DE (ST INGBERT) participant 502˙500.00
8    UNIVERSITY OF LEEDS UK (LEEDS) participant 490˙232.00
9    OZ BIOSCIENCES SAS FR (MARSEILLE) participant 480˙500.00
10    ASPHALION SL ES (BARCELONA) participant 318˙125.00

Map

 Project objective

The management and reconstruction of bone defects is a significant global healthcare challenge. While autografts offer ideal compatibility, they are often not suitable for large bone defects, and allografts suffer from potential immunorejection.The limited efficacy of conventional treatment strategies for large bone defects and the increasing aged population, has inspired the consortium to propose a SMART RESORBABLE BONE (SRB) IMPLANT embedding stem cells and bioactive agents with the aim of a controllable and fast restoration. The proposed solution includes 3D printed medical grade polymers enriched with electrospun fibers (for increased mechanical properties) that can be customized for patient physiology, pathology, and gender. The scaffold design will ensure easy and minimal Injury placement, and will embed different sensors for monitoring e.g. pressure, pH value and temperature based on biocompatible conductive inks. The smart implant will thus be able to provide vital information of implant performance in terms of bone growth and infection/inflammation. The proposed method is unique because it includes a customized smart implant (3D printed parts with adjustable sensors and communication electronic system), together with tissue engineering methods i.e. in-vitro programming of stem cells for embedding into the smart implant. The proposed solution introduces an innovative regenerative chain, from early testing and characterization (identification/adjustement of the proper specifications) and embedding regenerative stem cells and particulate bioactive agents into the smart implant in preclinical research (in-vitro). The in vivo proof of concept of SBR solution will be tested in (large animal model) preclinical studies within the scope of the project. Finally the regulatory and commercialization strategy on how to further explore the proposed concept and deliver it for clinical testing will be elaborated.

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The information about "SBR" are provided by the European Opendata Portal: CORDIS opendata.

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