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ISOTOPICS project deliverables

The page lists 27 deliverables related to the research project "ISOTOPICS".

 List of Deliverables

ISOTOPICS: list of downloadable deliverables.
title and desprition type last update

Network-wide Periodic Network meetings

Network-wide Periodic Network meetings at months 3, 10, 18, 26, 34, 42, 48 and associated reports at months 4, 11, 19, 27, 35, 43, 48

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Other 2020-03-27

Cascade reactions to construct 14C-heterocycles and derivatizing peptides and proteins from K14CN

New cascade reactions for the 14C labeling of small molecule (heterocyclic) drugs, peptides, and structurally begnign labeling of proteins from [14C]labeled KCN.

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

N-Methylation/C-carbonylation from CO2 for the [14C]radiolabeling of small-molecule drugs

N-Methylation/C-carbonylation from CO2 for the [14C]radiolabeling of small-molecule drugs. Evaluation of transferability to the [11C]radiolabeling of small-molecule drugs.

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Cu(III)-catalyzed [18F]fluorination of arenes and heteroarenes

Cu(III)-catalyzed [18F]fluorination of aryl boronic esters of arenes and heteroarenes motifs found in small-molecule drugs

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Development of new hydrophilic and air-resistant RuNps for [2H/3H]labeling of drugs & biologics

Development of new RuNPs with variable sizes, shapes, coating and poisoning to modulate their specificity and reactivity, and to improve their use in aqueous reaction media and their handling in the air.

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

New methods for [2H/3H]labeling of small molecules drugs and peptides

Development of innovative isotopic chemistry (in particular with RuNps) for the labeling of general molecular scaffolds with 2H and 3H and application to the isotopic labeling of simple molecules and then to small molecules drugs, peptides and short polynucleotides.

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Scientific meeting reports

Scientific meeting reports on months 4, 11, 27, 35, 43 and 48

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Dissemination of main results

Dissemination of main results throughout the consortium and outside (oral and poster presentations)

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Other 2020-03-27

Development, evaluation and applications of new methods for asymmetric [18F]fluorination

Development, evaluation and applications of new methods for asymmetric [18F]fluorination using chiral [18F]NF reagents, asymmetric organocatalysis and transition metal catalysts

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

New methods for [2H/3H]labeling of biologics

Application of the RuNps-catalyzed C-H activation of organic molecules to the [2H/3H] labeling of proteins, nucleic acids and other macromolecules

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Defence of PhD Thesis

Redaction and defense of Thesis for the awarding of the doctoral degree (according to host regulations)

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Development of a novel automated radio-chemistry system for [11C]carbonylation

Development (in collaboration with Scansys) of a novel automated radiochemistry system that allows for [11C]carbonylation to be performed according to GMP and thus enables clinical PET studies. In addition to transition metal catalysis, UV irradiation and/or chemical initiation will be performed to undertake radical [11C]carbonylation of alkyl substrates

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Training in information technology skills

Training in information technology skills, ability to get relevant scientific information from the current databases and application to research, project and grant writing and exploitation of results and data

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Microfluidic [11C]carbonylation screening under radical initiated conditions

Development of novel [11C]carbonylation radiochemistry methodology that will further progress the possibility to radiolabel drug-like molecules using a microfluidic synthesizer in reaction screening for the [11C]labeling of a set of representative drugs in particular under radical initiated conditions (undertaken in close collaboration with experts in radiochemistry hardware BenCar and Scancys)

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Results dissemination

Emphasizing the importance of dissemination of results through publications, industrial valorization, public engagement and participation to symposia

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Development of Suzuki protein chemistry for the [18F]labeling of proteins

Development of structurally benign Suzuki protein chemistry for the [18F]labeling of proteins through the Tag-and-Modify Strategy

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Improvement of employability

Improvement of employability through training in job search, career paths, management & entrepreneurship

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Network-wide interdisciplinary scientific training

Network-wide interdisciplinary scientific training composed of 5 Training Schools at months 10, 18, 26, 34, 42

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Websites, patent fillings, videos etc. 2020-03-27

Development of a photochemical flow process for addition of [18F]CHF to (hetero)aromatics

Development of a photochemical flow process for addition of [18F]CHF to (hetero)aromatic compounds through a radical process

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Development of new fluoro- and difluoromethyl-sulfonyl reagents for the production of [18F]labeled alkenes

Development of new fluoro- and difluoromethyl-sulfonyl reagents for the GMP production of [18F]labeled alkenes using cyclotron-produced [18F-]

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Public Engagement

Public Website, press release, Folk High Schools, Open days, Embassy

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Websites, patent fillings, videos etc. 2020-03-27

Website and Newsletters

Website and Newsletters regularly updated and sustained after the project completion (including partners websites)

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Websites, patent fillings, videos etc. 2020-03-27

Application of N-methylation and C-carbonylation from CO2 to [11C]labeling

Application of the carbonylation reactions from CO2 developed by CEA to the construction of [11C]labeled molecules and application to the [11C]labeling of small-molecule drugs.

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Patents, research and review publications, assistance for creation of start-ups and incubation

Patents, research and review publications, assistance for creation of start-ups and incubation, help to the writing of research projects

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-03-27

Supervisory Board of the Network

Effective nomination of the Supervisory Board of ISOTOPICS

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-02-17

Communication and presentation skills

Development of communication and presentation skills at group meetings and Network meeting as a preliminary training

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Documents, reports 2020-02-17

ESR recruitment process

Effective recruitment of all ESRs according to the priniciple of transparency and non-discrimination

Programme: H2020-EU.1.3.1. - Topic(s): MSCA-ITN-2015-ETN

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Other 2020-02-17