Explore the words cloud of the TRoMBONE project. It provides you a very rough idea of what is the project "TRoMBONE" about.
The following table provides information about the project.
CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO
|Coordinator Country||Portugal [PT]|
|Total cost||160˙635 €|
|EC max contribution||160˙635 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2017-04-01 to 2019-03-31|
Take a look of project's partnership.
|1||CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO||PT (COIMBRA)||coordinator||160˙635.00|
Given the poor regenerative potential of the adult heart after heart failure (HF), therapies capable of contributing for cardioprotection and cardio-regeneration are of great need. Recent advances in pharmacologic therapy and stem cells are currently not enough to address HF. The hypothesis of this project is that exosomes, nanovesicles secreted by cells may be a potential therapy for HF. Exosomes may offer advantages relatively to cell-based therapies regarding efficacy (does not require engraftment and survival), processing and cost. The main objective of the current project is to develop an effective strategy to deliver exosomes by intravenous (IV) injection into the heart (targeting) and to maximize exosome regenerative potential (bioactivity). Therefore, the project aims to develop a non-cellular-based therapy to regenerate the heart after infarction based on the targeted delivery of exosomes. Undertaking this research along with formal training and mentoring will enhance my academic profile, scientific experience, and content expertise in nanobiotechnology, to enable me to develop into an independent, leading researcher. The proposed research contributes to the EU priority of addressing the societal challenge of improving lifelong health and wellbeing of all.
|year||authors and title||journal||last update|
Arnab Banerjee, Vitor Alves, Tiago RondÃ£o, JosÃ© Sereno, Ã‚ngela Neves, Miguel Lino, Andreia Ribeiro, Antero J. Abrunhosa, Lino S. Ferreira
A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles
published pages: 13243-13248, ISSN: 2040-3364, DOI: 10.1039/c9nr02512j
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The information about "TROMBONE" are provided by the European Opendata Portal: CORDIS opendata.
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