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HINBOTS SIGNED

Highly Integrated Nanoscale Robots for Targeted Delivery to the Central Nervous System

Total Cost €

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EC-Contrib. €

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Partnership

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 HINBOTS project word cloud

Explore the words cloud of the HINBOTS project. It provides you a very rough idea of what is the project "HINBOTS" about.

assemblies    host    gates    integrate    theatre    invasive    myriad    structures    molecular    models    multiferroic    power    piezoelectrochemical    sources    over    miniaturized    machines    perform    first    sought    minimally    machinery    rewiring    central    agents    act    nanorobots    ultimately    entities    active    release    nervous    made    gated    moving    consists    harvesting    payloads    neural    robots    supramolecular    media    multiferroics    time    delivering    redox    environments    platforms    multifunctional    cargo    magnetoelectric    synthetic    chassis    circuitry    electrostimulating    robotics    sites    piezoelectric    remotely    realizing    ranging    ultimate    smart    acoustic    capitalizing    fuel    onto    electroresponsive    functions    inorganic    triggered    create    interventions    surrounding    micro    nanomaterials    demonstrated    porous    navigate    grafted    decades    reduce    loaded    demand    magnetic    animal    discomfort    risk    chemistry    materials    small    external    surface    therapeutic    conventional   

Project "HINBOTS" data sheet

The following table provides information about the project.

Coordinator
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH 

Organization address
address: Raemistrasse 101
city: ZUERICH
postcode: 8092
website: https://www.ethz.ch/de.html

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 1˙998˙720 €
 EC max contribution 1˙998˙720 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-COG
 Funding Scheme ERC-COG
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2023-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) coordinator 1˙998˙720.00

Map

 Project objective

Over the past two decades researchers have been working to create synthetic small-scale machines ranging from molecular entities or miniaturized structures, to more complex assemblies of micro- and nanomaterials. These machines are able to navigate in complex environments by harvesting fuel from the surrounding media or from external power sources. One of the most sought-after applications for these miniaturized machines is to perform minimally invasive interventions, in which these devices will ultimately reduce risk, cost, and discomfort compared to conventional interventions. This has driven researchers to produce a myriad of small-scale robots loaded with therapeutic cargo. While recent research has demonstrated the potential of these devices in animal models, a number of challenges remain in moving small-scale robots into the operating theatre. Here, we propose highly integrated nanorobots capable of realizing several functions on-demand by capitalizing on recent developments in small-scale robotics, multiferroics, supramolecular chemistry, and gated materials. These nanorobots will integrate a porous inorganic active chassis made of a piezoelectric or a magnetoelectric multiferroic that will host therapeutic agents, with redox or electroresponsive supramolecular gates that will control the release of payloads. We will demonstrate for the first time that redox- and electroresponsive supramolecular machinery grafted onto the surface of piezoelectric or multiferroic platforms can be remotely controlled by means of a piezoelectrochemical potential triggered by acoustic and magnetic fields. The ultimate goal of this research consists of creating smart multifunctional nanorobots, which will act on affected sites of the central nervous system by delivering therapeutic agents and electrostimulating the rewiring of neural circuitry.

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The information about "HINBOTS" are provided by the European Opendata Portal: CORDIS opendata.

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