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Host Sweet Home TERMINATED

Unravelling the mechanisms that allow endosymbionts to make themselves at home within hosts, from transfer to transit.

Total Cost €

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EC-Contrib. €

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Partnership

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Project "Host Sweet Home" data sheet

The following table provides information about the project.

Coordinator
LUNDS UNIVERSITET 

Organization address
address: Paradisgatan 5c
city: LUND
postcode: 22100
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Project website http://www.anneduplouy.net
 Total cost 185˙857 €
 EC max contribution 185˙857 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2021-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    LUNDS UNIVERSITET SE (LUND) coordinator 185˙857.00

Map

 Project objective

Endosymbiotic bacteria are usually not infectious, they have been thought to exclusively transfer vertically from the host mother to her offspring. Consequently we do often observe congruence between the phylogenetic trees of endosymbiotic bacteria and their host species, but not always. Evidences for the horizontal transfer of endosymbiotic bacteria between highly divergent host species have recently been accumulating, especially from studies in Insects. My own research on this topic led me to hypothesise that endosymbiotic strains not transferring horizontally may have lost the ability to do so and to establish into naïve hosts, contrasting to strains found in divergent host species. Instead of transferring, these strains would transit from a generalist state, able to jump and establish into naïve hosts, towards a more specialist state found in only few host species. Using Wolbachia bacteria-butterfly host associations and a multidisciplinary approach, I aim at (I) testing the evolutionary relevance of horizontal transfer of symbionts, (II) phenotypically characterizing generalist and specialist symbionts, and (III) identifying the molecular bases to the establisment of symbiosis. The novelty of this project lies into solving the dilemma associated to the endosymbiotic lifestyle: to maintain the mechanisms allowing transfer between hosts or to transit towards a specialised relationship with the host. ‘Host Sweet Home’ will to unravel the evolutionary history, and the constraints and outcomes of endosymbiosis. I will produce a large amount of genetic data, which analysis will result in highly significant research in the field of symbiosis, with a potential impact beyond the field of Evolutionary Ecology.

 Publications

year authors and title journal last update
List of publications.
2020 Anne Duplouy, Guillaume Minard, Marjo Saastamoinen
The gut bacterial community affects immunity but not metabolism in a specialist herbivorous butterfly
published pages: , ISSN: , DOI: 10.21203/rs.2.21629/v1
Research Square 2020-04-16
2019 J. Dylan Shropshire, Brittany Leigh, Sarah R. Bordenstein, Anne Duplouy, Markus Riegler, Jeremy C. Brownlie, Seth R. Bordenstein
Models and Nomenclature for Cytoplasmic Incompatibility: Caution over Premature Conclusions – A Response to Beckmann et al.
published pages: 397-399, ISSN: 0168-9525, DOI: 10.1016/j.tig.2019.03.004
Trends in Genetics 35/6 2020-04-16
2019 Andreia Miraldo, Anne Duplouy
High Wolbachia Strain Diversity in a Clade of Dung Beetles Endemic to Madagascar
published pages: , ISSN: 2296-701X, DOI: 10.3389/fevo.2019.00157
Frontiers in Ecology and Evolution 7 2020-04-16
2019 Isa Bengzon
Screening for infection by the endosymbiotic bacteria Wolbachia pipientis in Russian Melitaea butterflies
published pages: , ISSN: , DOI:
2020-04-16

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The information about "HOST SWEET HOME" are provided by the European Opendata Portal: CORDIS opendata.

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