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PermeAbility SIGNED

PermeAbility - A non-invasive, side-effect-free diagnostic kit for intestinal disorders

Total Cost €

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EC-Contrib. €

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Partnership

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 PermeAbility project word cloud

Explore the words cloud of the PermeAbility project. It provides you a very rough idea of what is the project "PermeAbility" about.

besides    ibd    compromises    plasma    biopsy    burden    diagnosis    barrier    billion    acute    markers    causes    obesity    stool    decision    disposing    symptoms    economic    stream    threats    syndrome    damage    quality    reinforced    wall    diagnosed    diabetes    digestion    cells    select    compromise    rheumatoid    informed    bowel    rupture    urges    food    blood    intestinal    inflammatory    direct    diarrhea    permeability    intestine    dramatic    toxic    patients    restricted    lesions    facts    risk    leak    clear    poses    proprietary    people    arthritis    performed    solely    life    disease    lgs    assessing    lifetag    ulcers    mri    articles    waste    structure    removal    particles    gut    treatment    colonoscopy    small    though    normally    causing    abdominal    evaluation    unnecessary    limited    health    form    invasive    qualitative    diagnostic    bacteria    reported    tightly    connected    clinical    maintaining    organization    bleedings    leaky    heavy    pain    indirect    revealing    worldwide    surgeries    description    extensive    35    inflammation    microcapsule   

Project "PermeAbility" data sheet

The following table provides information about the project.

Coordinator
LIEFTAG LDA 

Organization address
address: BIOCANT - ASSOCIACAO DE TRANSFERENCIA DE TECNOLOGI
city: CANTANHEDE
postcode: 3060 197
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Project website https://lifetag.pt
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-08-01   to  2019-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    LIEFTAG LDA PT (CANTANHEDE) coordinator 50˙000.00

Map

 Project objective

'Inflammatory Bowel Disease (IBD) is a form of acute inflammation to the small intestine that causes ulcers and extensive damage of the gut barrier causing it to rupture. This causes bleedings, abdominal pain, diarrhea, and a dramatic reduction of the quality of life. The intestinal barrier is normally a very well organised structure in which the cells are tightly connected maintaining the barrier. Moreover, IBD lesions compromise this intestinal organization and increases intestinal permeability, which is called leaky gut syndrome (LGS) being also a pre-disposing factor for several other health problems. LGS compromises digestion of food particles and removal of toxic waste products, and allows bacteria to 'leak' through the intestine to the blood stream. Besides in IBD, LGS is also common in people with health conditions such as obesity, rheumatoid arthritis and type 2 diabetes. Even though IBD poses significant threats to a patients’ health and a heavy direct and indirect economic burden, diagnosis of this condition is still limited assessing indirect parameters like general inflammation markers in plasma and stool and evaluation based by comparison on the patients symptoms description. The direct measures are also performed but are restricted to very invasive methods like biopsy or solely qualitative like MRI and microcapsule colonoscopy. In this way it is reported in several clinical articles a clear need for new diagnostic methods in IBD reinforced by facts like 35% of the performed surgeries for treatment revealing unnecessary and 1.9 billion people worldwide at risk for early lesions and IBD development not being diagnosed. In this way clinical practice urges for new methods for the assessment of lesions in the intestinal wall. Lifetag’s has developed PermeAbility, a new proprietary test to measure intestinal permeability to better select patients at high risk of IBD , leading to better informed clinical decision making, diagnosis, and treatment.'

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The information about "PERMEABILITY" are provided by the European Opendata Portal: CORDIS opendata.

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