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DNANanoProbes SIGNED

Design of light-harvesting DNA-nanoprobes with ratiometric signal amplification for fluorescence imaging of live cells.

Total Cost €

EC-Contrib. €

Partnership

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DNANanoProbes project word cloud

Explore the words cloud of the DNANanoProbes project. It provides you a very rough idea of what is the project "DNANanoProbes" about.

single innovative dyes functionalized phenomenon groundbreaking facilities shell techniques predicated fluorescent nanosensors sequences signal acids technique amplification laboratory light organic giant spectroscopy probes incorporated nanoparticles synthesis cells microscopy polymer nucleic bioconjugation group living host dna ultrabright nps interdisciplinary copy contemporary harvesting rna relies detection

Project "DNANanoProbes" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITE DE STRASBOURG Organization address address: RUE BLAISE PASCAL 4 city: STRASBOURG postcode: 67081 website: http://www.unistra.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	France [FR]
Total cost	196˙707 €
EC max contribution	196˙707 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2018
Funding Scheme	MSCA-IF-EF-ST
Starting year	2019
Duration (year-month-day)	from 2019-05-15 to 2021-05-14

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITE DE STRASBOURG UNIVERSITE DE STRASBOURG Organization address address: RUE BLAISE PASCAL 4 city: STRASBOURG postcode: 67081 website: http://www.unistra.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (STRASBOURG)	coordinator	196˙707.00

Map

Project objective

The project is aimed to develop the novel technique of fluorescent signal amplification upon detection of RNA sequences in living cells up to a single copy level. The novel interdisciplinary approach will be focused on design of innovative fluorescent nanosensors based on polymer nanoparticles (NPs) incorporated with organic dyes, functionalized with DNA shell. The project is predicated on the innovative design of DNA-nanosensors, proposed by the Applicant, which is built on groundbreaking findings of the Host laboratory on ultrabright organic NPs and giant light-harvesting phenomenon that enable strong amplification in detection of nucleic acids. The project relies on contemporary spectroscopy/microscopy facilities and developments of the Host group, and the strong experience of the Applicant in synthesis of fluorescent dyes, design of DNA-probes and bioconjugation techniques.

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The information about "DNANANOPROBES" are provided by the European Opendata Portal: CORDIS opendata.