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MOBETA SIGNED

Motor cortical beta bursts for movement planning and evaluation: Mechanisms, functional roles, and development

Total Cost €

0

EC-Contrib. €

0

Partnership

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 MOBETA project word cloud

Explore the words cloud of the MOBETA project. It provides you a very rough idea of what is the project "MOBETA" about.

region    actions    oscillatory    discrete    beta    evaluation    trials    sensory    trial    overturn    cut    actually    averaged    basis    longitudinal    lasting    recordings    online    monkey    bursts    ongoing    neuroimaging    behavioral    line    networks    30hz    modeling    apparent    relatively    movement    involve    disorders    course    frequency    multiple    columns    straight    integration    untenable    provides    extend    hallmark    personalized    scissors    human    signature    implications    occurs    interplay    relevance    electrophysiological    relate    button    invasive    transient    substantially    cortical    computational    oscillations    examine    theory    behavior    muscle    infants    paper    sheet    performs    appear    each    daily    aberrant    treatments    motor    forthcoming    sustained    13    power    developmental    thousands    modal    mouse    holding    powered    pathophysiological    intricate    renders    pathological    thinking    opportunity    signaling    theories    healthy    clicking    functional    slow    unclear    ranging   

Project "MOBETA" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 1˙988˙189 €
 EC max contribution 1˙988˙189 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-COG
 Funding Scheme ERC-COG
 Starting year 2020
 Duration (year-month-day) from 2020-06-01   to  2025-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 1˙988˙189.00

Map

 Project objective

Each of us performs thousands of actions during the course of daily tasks, ranging from relatively simple (e.g. clicking on a mouse button), to highly complex (e.g. holding a sheet of paper in one hand while using scissors to cut it in a straight line with the other). All of these actions involve an intricate interplay between sensory integration, muscle coordination, and movement evaluation processes. Motor cortical activity in the beta frequency range (13-30Hz) is a hallmark signature of healthy and pathological movement, but its behavioral relevance remains unclear. Recently, it has become apparent that oscillatory beta activity actually occurs in discrete, transient bursts, and that short-lasting, high-powered bursts of activity only appear to be sustained oscillations when averaged over multiple trials. This renders previous theories of beta activity’s functional relevance, which involve slow changes of oscillatory power, untenable. However, this insight provides an exciting opportunity to examine beta activity on a trial-by-trial basis and directly relate it to forthcoming and ongoing motor behavior. Here, I propose a new theory for understanding motor-related beta activity that has the potential to overturn current thinking of the motor role of beta. The proposed project will build upon my recent research and use a multi-modal (electrophysiological recordings, non-invasive neuroimaging, and computational modeling), multi-scale (from cortical columns to multi-region networks), comparative (monkey and human), and developmental (longitudinal measures of human infants) approach to develop and test this theory. Not only will results from this project substantially extend our knowledge on the role of motor-related beta activity, they will have important implications for personalized, online treatments for pathophysiological disorders characterized by aberrant beta signaling.

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The information about "MOBETA" are provided by the European Opendata Portal: CORDIS opendata.

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