Opendata, web and dolomites

H2020 projects about "mouse"

The page lists 655 projects related to the topic "mouse".

# achronym  title  year 
1 FAIR-PARK-II Conservative iron chelation as a disease-modifying strategy in Parkinson’s disease: a multicentric, parallel-group, placebo-controlled, randomized clinical trial of deferiprone 2015
2 GermAge The aging germ cell – biological pathways, risk factors and mechanisms underlying an increasing medical and socio-economic problem 2015
3 PentaBrain Structural studies of mammalian Cys-loop receptors 2015
4 BREATHE Biochemically modified messenger RNA encoding nucleases for in vivo gene correction of severe inherited lung diseases 2015
5 QUANTPATTERN Quantitative analysis of Nodal/Lefty-mediated pattern formation 2015
6 INTRAHETEROSEQ Molecular characterization of the role of intra-tumor heterogeneity in cancer progression and metastasis 2015
7 NEUROMITO Elucidating Neuronal Susceptibility to Mitochondrial Disease 2015
8 ApoptoMDS Hematopoietic stem cell Apoptosis in bone marrow failure and MyeloDysplastic Syndromes: Friend or foe? 2015
9 CIRCUITASSEMBLY Development of functional organization of the visual circuits in mice 2015
10 FLDcure A potent Micro-RNA therapeutic for nonalcoholic fatty liver disease (NAFLD) 2015
11 Oscillations Oscillatory signaling dynamics – a quantitative approach to reveal their origin and function in development 2015
12 aCROBAT Circadian Regulation Of Brown Adipose Thermogenesis 2015
13 LOCOMOUSE Cerebellar circuit mechanisms of coordinated locomotion in mice 2015
14 TIME SCALE Technology and Innovation for Development of Modular Equipment in Scalable Advanced Life Support Systems for Space Exploration 2015
15 DHaptics DHaptics: Creating silent and sharp Mid-air Haptics using phased array of ultrasound transducers 2014
16 VEGFDANI Novel enhancers of functional recovery after stroke 2015
17 TheLiRep Exploring the Potential for Therapeutic Lineage Reprogramming of Diabetes 2015
18 Fingers4Cure Zinc finger gene therapy in the brain for treating Huntington's disease 2015
19 BonePain European Training Network on Bone Pain 2015
20 MAMEM Multimedia Authoring and Management using your Eyes and Mind 2015
21 LYMPHORG Organ-specific mechanisms of lymphatic vascular development and specialisation 2015
22 SynChI Striatal cholinergic cell assemblies in movement disorders 2015
23 CancerHetero Dissection of tumor heterogeneity in vivo 2015
24 BODY-UI Using Embodied Cognition to Create the Next Generations of Body-based User Interfaces 2015
25 MICEXPRESS Understanding how selection for body weight in mouse operates at the RNA level 2015
26 MitSyn Alpha-synuclein and mitochondrial dysfunction: key links between Gaucher’s disease and Parkinson’s? 2015
27 IPAD-MD Research Infrastructures for Phenotyping, Archiving and Distribution of Mouse Disease Models - Promoting International Cooperation and User Engagement to Enhance Biomedical Innovation 2015
28 PRDM9Recomb The Evolution of PRDM9 Binding and Genomic Localization of Meiotic Recombination Events 2015
29 OTULINVIVO The role of OTULIN and Met1-linked ubiquitin in immune signaling and host defense in vivo 2015
30 CircaDopamine The Role of Dopamine in the Regulation of Sleep and Circadian Rhythms 2015
31 IgEPath IgEPath - Contributions of IgE-antibodies and IgE effector cells to host defense against pathogenic bacteria 2015
32 ESATM Embryonic stem cell origin of the adipose tissue macrophages 2015
33 GutILC3 Cell-cell interactions critical to ILC3 function in the human gut 2015
34 AllergyBLOCK Blocking peanut allergy through protective IgG antibodies 2015
35 MecaMorphEME Four-dimensional physical modeling and numerical simulation of the early mouse embryo morphogenesis. 2015
36 MoTOR Analysis of the “moonlighting” proteins in the mTOR-signalling pathway 2016
37 GUTWORM Unravelling host intestine-parasite interactions that define immune responses to whipworms 2015
38 TANYFEEDNEURONS Gliotransmission and shuttling of metabolic signals to feeding neuronal circuits by tanycytes 2015
39 FE-RUS-Blast Finite Element Resonant Ultrasound Spectroscopy to Characterize Maturation of Cortical Bone Elastic Properties 2015
40 GLUCOTOX Does reducing β-cell glucotoxicity increase the hyperglycaemia-lowering effect of physical exercise in type 2 diabetes? 2015
41 Class II PI3K Characterization of the signalling and physiological roles of the class II PI3Ks 2016
42 EDPAS Regulation of early embryo development and pluripotency through alternative splicing 2015
43 REDOxHEART The Role of Adipose-Tissue Derived wnt-ligands in the Regulation of Myocardial Redox Signalling 2015
44 DC cancer Development and immunological control of dendritic cell cancer 2015
45 RNA-SHAPE Structure and function of repeat-derived non-coding RNAs in epigenetic regulation of mammalian pericentric heterochromatin 2015
46 embryonic rosettes Investigating embryonic development at the time of implantation using embryos and ES cells 2016
47 iRhom2 in AD iRhom2 in neuroinflammation and pathogenesis of Alzheimer’s Disease 2015
48 PromoTeRapy Haploinsufficiency and Intractable Epilepsy Rescue Increasing Endogenous Gene PromoterEfficiency 2016
49 DYS_FUNCTION Novel use of exon skipping technology to study structure-function relationship of dystrophin 2016
50 HAT-MOZ-sphere Identification of genes and pathways regulated by the HAT activity of MOZ 2015
51 GLYCODIS3 Genetic correction of glycogen debranching enzyme deficiency in Glycogen Storage disease III: a proof of concept study 2016
52 Als-on-a-chip A tissue-on-a-chip platform for systems-level studies of ALS pathology and drug screening 2015
53 HGSOC A novel approach into modeling origin and development of ovarian cancer 2015
54 NovLeuReg Identification and characterization of novel essential regulators of acute myeloid leukemia 2016
55 Subpopulations Investigating Fibrotic and Regenerative Fibroblast Populations in Muscular Dystrophy 2016
56 Glial-Puberty The role of Glial cells in the control of puberty 2016
57 CICCI Characterization of Intestinal Cancer Cell Invasion 2015
58 FiBRO Fibroblasts in the Biology of Rectal Cancer Progression 2016
59 ZPVMH Synaptic integration in the ventromedial hypothalamic nucleus in aggressive behaviour 2015
60 Tbet ILC JFN The role of innate lymphoid cells in regulating intestinal inflammation 2015
61 miRNAs in TH2 cells Role of extracellular miRNAs in T cell development, TH2 cell differentiation and TH2 cell-mediated effector function 2015
62 MatrixMacrophages Matrix degrading macrophages in cancer growth and invasion 2015
63 IntestineUb The role of Ubiquitin System on the homeostatic control of stem cell maintenance and differentiation in crypt stem cells 2016
64 ACM Cholesterol metabolism as a driver of prostate cancer aggressiveness 2015
65 S-OS Exosomes as microenvironmental cue for engaging mesenchymal stem cells in osteosarcoma progression 2016
66 MIRAGE MicroRNAs as therapeutic targets for ARVC. 2015
67 GABACODEV Role of GABAergic microcircuits with different embryonic origins in the orchestration of early cortical dynamics in the awake mouse pup 2015
68 PIOMES Pbx proteins as pioneer factors promoting signal specificity in mesodermal differentiation 2015
69 REPTIMORG DNA replication timing and spatial organization of chromatin 2016
70 Athero MPh proliferation Macrophage proliferation and ontogeny in murine models of atherosclerosis 2016
71 DENDRITESONBORDERS Neuronal and dendritic recruitment on neocortical area borders 2016
72 EPIGENHEART Epigenetic control of retinoic acid-dependent genes during heart development 2015
73 REBuILD Exploring the role of TFEB in exosome biology and in novel approaches for treatment of lysosomal diseases 2016
74 HepatoRiSK A new tumor suppressor role for RSK2 in hepatocellular carcinoma 2015
75 InCisive creTRAP for in situ Characterization of Fibrosis-Promoting Pathways in Non-alcoholic Fatty Liver Disease 2016
76 DUALgRENP A DUAL gRNA system for functional assessment of ENhancers in Pluripotency 2016
77 HUMICE AXENIS Humanized Mice – Innovation towards industrial scale-up 2015
78 GAMES Gut Microbiota in Nervous System Autoimmunity: Molecular Mechanisms of Disease Initiation and Regulation 2015
79 ONCOMECHAML Common Oncogenic Mechanisms in Multi-Partner Translocation Families in Acute Myeloid Leukemia 2015
80 HBV1 Innate immune responses to human hepatotropic viral infections 2015
81 TWILIGHT ToWards Immunisations that Last: the Immunology and Gerontology of Helper T cells 2015
82 FAtoUnFRAGILITY Fanconi anemia : a disease model to understand causes and consequences of common fragile site instability. 2015
83 HybridMiX Genetic Mapping of Evolutionary Developmental Variation using Hybrid Mouse in vitro Crosses 2015
84 Enhancer ID Identification and functional characterization of mammalian enhancers and transcriptional co-factors during cellular signaling and cell fate transitions 2015
85 NEWCARBOVAX New generation of carbohydrate-based vaccines via rational understanding of their immunological mechanism 2017
86 MRG-GRammar Massive Reverse Genomics to Decipher Gene Regulatory Grammar 2015
87 Dementia DNA rEpair impaired Mice with accElerated Neurodegeneration as Tool to Improve Alzheimer therapeutics 2015
88 OPTIMALZ Optical imaging of ocular pathology in Alzheimer’s disease 2015
89 EVOMESODERM The evolution of mesoderm and its differentiation into cell types and organ systems 2015
90 UBIQUO PLATFORM TO DEVELOP AND DISTRIBUTE GESTURE RECOGNITION BASED APPLICATIONS 2015
91 MISTRANSMITO Tissue-specific mitochondrial signaling and adaptations to mistranslation 2015
92 PERSYST Generation and maintenance of long-lived memory T cells in humans 2015
93 PULTAR Delivery of PULmonary Therapeutics through TARgetted Delivery using Phononics 2015
94 INNOPREFAT Natural Food formulation for the prevention and treatment the Obesity and Metabolic syndrome obtained with herbal extracts 2015
95 CIGUALERT Reference standards for a specific, reliable and early detection of the marine toxins that causes ciguatera disease 2015
96 TEC_Pro Molecular control of self-renewal and lineage specification in thymic epithelial cell progenitors in vivo. 2015
97 DevoTed_miR MicroRNA determinants of the balance between effector and regulatory T cells in vivo 2015
98 D-FENS Dicer-Dependent Defense in Mammals 2015
99 RENOIR RENal prOgenItoRs as tools to understand kidney pathophysiology and treat kidney disorders 2015
100 BRAINSTRUCT Building up a brain: understanding how neural stem cell fate and regulation controls nervous tissue architecture 2015
101 MetCAF Uncovering the Role of Cancer Associated Fibroblasts in Facilitating Breast Cancer Metastasis 2015
102 YOUNGatHEART YOUNGatHEART: CARDIAC REJUVENATION BY EPIGENETIC REMODELLING 2015
103 TIPPDECRA Tolerogenic immunotherapy with peptide-pulsed dendritic cells in rheumatoid arthritis 2016
104 BeadDiagnosis Prognosis and Diagnosis of Protein Misfolding Diseases by Seeded Aggregation in Microspheres 2015
105 RegulHox Topological organization of vertebrate regulatory landscapes: The Hox genes paradigm 2015
106 STARS Strategies Targeting Thyroid Hormone in Athrophy Related Syndromes 2015
107 STROMA IMMUNOBIOLOGY OF LYMPHOID STROMAL CELLS 2015
108 OxygenSensing Molecular mechanisms of acute oxygen sensing. 2015
109 Novel asthma therapy Biocompatible nanoparticles for T cell targeted siRNA delivery as novel asthma therapy 2015
110 MetAGEn Metabolic and Genetic Regulation of Ageing 2015
111 UPR NEURO The Unfolded Protein Response in Neurodegeneration 2015
112 COMAL COMAL:COhesin Mutations in Acute Leukemia: from modeling and mechanisms to novel therapeutics 2015
113 NEURO-PATTERNS How neuronal activity patterns drive behavior: novel all-optical control and monitoring of brain neuronal networks with high spatiotemporal resolution 2015
114 dynamicmodifications Complexity and dynamics of nucleic acids modifications in vivo 2015
115 Titin Signals Molecular dissection of titin-based mechanisms in charge of cardiomyocyte dysfunction in terminal feart failure 2016
116 SIRENE Silencing miR-199b to attenuate the progression of heart failure. 2015
117 PHII PTX3 in Humoral Innate Immunity 2015
118 Phd Deciphering PI3K biology in health and disease 2015
119 ISPIC Image-Guided Surgery (IGS) and Personalised Postoperative Immunotherapy To Improving Cancer Outcome 2016
120 HaemMetabolome Deciphering the Metabolism of Haematological Cancers 2015
121 CholangioConcept Functional in vivo analysis of cholangiocarcinoma development, progression and metastasis. 2015
122 SYNPRIME Presynaptic Regulatory Principles in Synaptic Plasticity, Neuronal Network Function, and Behaviour 2015
123 REGMAMKID How to regenerate the mammalian kidney 2015
124 NeuroPioneers A developmental engram for the organization of adult hippocampal circuits 2015
125 XChromosome Functions of the X chromosome in the mammalian germ line 2015
126 NEURIMMUNE Neural regulation of immunity 2015
127 RNAEDIT RNA EDITING IN HEALTH AND DISEASE 2016
128 CELLPLASTICITY New Frontiers in Cellular Reprogramming: Exploiting Cellular Plasticity 2015
129 SIMBIONT A data-driven multiscale simulation of organogenesis 2015
130 AVATAR Integrating Genomics and Avatar Mouse Models to Personalize Pancreatic Cancer Treatment 2015
131 MMUVR Elucidating the role of ultraviolet radiation in melanoma 2016
132 SLACC Supplying lung adenocarcinoma cell lines to the cancer research community. 2015
133 CellViewer CellViewer: super-resolution systems microscopy to assess pluripotency and differentiation of stem cells at single cell level 2016
134 ThDEFINE Re(defining) CD4+ T Cell Identities One Cell at a Time 2016
135 EDeN Ependymal cell Development: New insight into neurological diseases 2015
136 PanCaT Next-generation in vivo models for improved pancreatic cancer therapies 2016
137 BATCure Developing new therapies for Batten disease 2016
138 Angiolnc Endothelial long non-coding RNAs 2016
139 HEP-CAR Mechanisms underlying hepatocellular carcinoma pathogenesis and impact of co-morbidities. 2016
140 Click-It “In Vivo Click PET Imaging Agents”: Improving clinical companion diagnostics 2016
141 SysMedPD Systems Medicine of Mitochondrial Parkinson’s Disease 2015
142 EPIROSE Self-Organising Capacity of Stem Cells during Implantation and Early Post-implantation Development: Implications for Human Development 2016
143 NEUROVESSEL Cell-cell interactions at the neurovascular interface 2016
144 ZF-BrainReg Regeneration of the adult zebrafish brain 2016
145 CFS modelling Chromosomal Common Fragile Sites: Unravelling their biological functions and the basis of their instability 2016
146 WebMAT Web-based system for multi-arrangement task for rapid acquisition of subjectivejudgements. 2016
147 ERAofART Epigenetic Risk Assesment of Assisted Reproductive Technologies 2016
148 IMPEDE Immunomodulatory effects of sustained pantethine release in inflammatory diseases 2016
149 GROWTHPATTERN Coordination Of Patterning And Growth In The Spinal Cord 2016
150 FOLSMART Folate-Target Nanodevices To Activated Macrophages For Rheumatoid Arthritis 2016
151 MECHANOGENOMICS Unravelling mammalian mechanosensor diversity by functional genomics 2016
152 ETIC Encoding and Transmission of Information in the Mouse Somatosensory Cortex 2016
153 GvHDCure Understanding the dynamics of the immune system to cure graft-versus-host disease (GvHD). 2016
154 PARPin Regulation of (ADP-ribosyl)ation signalling in the DNA damage response: elucidating the function of a novel PARP1/ARTD1 interactor 2016
155 DRIVOME Multi-modal interrogation of instinctive behaviours and intrahypothalamic connectivity 2016
156 CMIL Crosstalk of Metabolism and Inflammation 2016
157 NEUROGOAL Neuronal Coding of Choice and Action-Selection during Decision-Making in Behaving Mice 2016
158 HOLDING-HANDS Holding hands: cell-cell junctions in breast cancer metastasis and resistance to therapy 2016
159 AXIAL.EC PRINCIPLES OF AXIAL POLARITY-DRIVEN VASCULAR PATTERNING 2016
160 PSYCHOCELL Cellular substrate of abnormal network maturation in neuropsychiatric disorders 2016
161 TARG-SUP Targeting TGF-β activation, likely the core mechanism of immunosuppression by human regulatory T cells. 2016
162 CanPathPro Generation of the CanPath prototype - a platform for predictive cancer pathway modeling 2016
163 MICRO-MACRO-ILC Dissecting the human microbiota-macrophage-innate lymphoid cell crosstalk in the lung 2016
164 EPILIPRO Elucidating the role of Arid1a in adult liver 2016
165 MCNTMTDC Metabolic control on NF-κB activity during dendritic cells-mediated immune tolerance to tumours 2017
166 PlaEndo The Remote Control of Maternal Metabolism by the Placenta 2016
167 iGEMMdev Development and Characterisation of New Immunogenic GEMMs of Lung Cancer 2017
168 RETICULUS Integration of retinal inputs by distinct collicular cell types 2017
169 SKINFRET The involvement of epidermal stem cells in spatiotemporal ERK activity propagation 2016
170 INTEGRISTEM Functions of Integrins in Mammary Stem Cell Activity and Tumorigenesis 2016
171 Dynamic Perspectives Unravelling perspective-taking: Examining the influence of multiple constraints on perspective selection and multimodal behavior through a dynamical systems' approach 2016
172 MPSC Membrane Potential and Stem Cell Potency in Normal and Malignant Tissues 2016
173 NuSiCC Modelling the therapeutic potential of NUAK1 suppression in colorectal cancer 2016
174 CorCir Cortical circuit assembly in the developing mouse neocortex 2017
175 LIPSYNING Eat me microglia: lipid scrambling as a signal for synaptic pruning 2016
176 MONOCLE A novel enhancer deletion strategy to determine non-classical monocyte function in atherosclerosis 2017
177 NeuroASPECT Neuronal Alternative Splicing and RNA-Editing Crosstalk 2017
178 KILLINGTYPHI Identification of host-factors restricting Salmonella Typhi 2016
179 XPGCS Single cell profiling of X chromosome reactivation during primordial germ cell specification in vivo 2016
180 MAIT Evolutionary conserved T cells specific for a microbial metabolite: deciphering their development in the thymus and mapping their interactions with the gut microbiota in vivo. 2016
181 GRNHairCell Understanding the Gene Regulatory Network involved inner ear Hair Cell differentiation 2016
182 AVITAG Alphaviral Immunotherapy against Glioblastoma 2016
183 Gut-InflammAge Age-associated signatures in the composition and pro-inflammatory status of the gut microbiome in humans and mice, and the impact of a periodic fasting intervention to promote healthy aging 2016
184 PERICYTEStroma Pericyte-derived tumor stroma – a target for cancer therapy 2016
185 MiroMigration Miro dependent mitochondrial dynamics and the regulation of neuronal migration 2016
186 EpiMIRgen A comprehensive analysis of microRNA-124 regulated gene networks and its role in epilepsy. 2016
187 RAC Defining the Role of Antioxidants on Cancer progression and metastasis 2016
188 ZF-ILC Characterization of zebrafish innate lymphoid cells and IL-22 2017
189 ADHDLightUp Circuit-based deconstruction of Attention deficit and Hyperactive disorder with optogenetic Light control 2016
190 NVHSC Neurovascular interplay in the hematopoietic stem cell niches in homeostasis and myeloproliferative neoplasias 2016
191 STrkB The structural biology of TrkB-BDNF signalling 2017
192 ChondUb Identification and characterisation of novel WWP2 substrates and their role in chondrogenesis and osteoarthritis 2016
193 CureCKDHeart Targeting perivascular myofibroblast progenitors to treat cardiac fibrosis and heart failure in chronic kidney disease 2016
194 TransposonsReprogram How retrotransposons remodel the genome during early development and reprogramming 2016
195 OPTIM Optimized drug combinations for effective cancer treatment: a personalised approach. 2016
196 SYNVIA Synthetic viability of homologous recombination-deficient cancers 2016
197 TSGPs-of-CFSs Role of Tumour Suppressor Gene Products of Common Fragile Sites in Human Diseases 2016
198 ONCOINTRABODY Targeting common oncogenes with intracellular monobodies 2016
199 GCB-PRID Post-transcriptional Regulation of Germinal Center B Cell Responses in Immunity and Disease 2016
200 FLUORODRUGS Smart Theranostic Agents for the Tumour Microenvironment 2017
201 MITOBIOPATH DISCOVERING NEW DISEASE PATHWAYS AFFECTING mtDNA METABOLISM 2016
202 defence_SC Computation of innate threats and defensive behaviour in the mouse 2017
203 NeuralCoding Probing principles of neural coding with all-optical interrogation in behaving mice 2017
204 TransGen RNA Transgenerational regulation of glucose metabolism by noncoding RNAs 2016
205 REpiReg RNAi-mediated Epigenetic Gene Regulation 2017
206 AD-gut Alzheimer Disease - gut connection 2016
207 MultisensoryIntegration Multisensory Integration in Time and Space 2016
208 VisNav Vision and Navigation in Mouse Cortex 2016
209 HEAL-BY-MIRNA microRNA replacement therapy for mature B cell neoplasias 2016
210 BoneMalar Mechanisms of bone marrow sequestration during malaria infection 2016
211 DENOVOMUT An integrated approach to understanding the impact of de novo mutations on the mammalian genome 2017
212 Toxoplasma sensing Cytoplasmic sensing of Toxoplasma gondii infection and host cell programmed necrosis 2016
213 AG-GF Behavior-dependent interactions between frontal and somatosensory cortices 2016
214 MERC Molecular mechanisms regulating cardiovascular remodeling by Adamts1 2016
215 Antibodyomics Vaccine profiling and immunodiagnostic discovery by high-throughput antibody repertoire analysis 2016
216 AFTAT “Animal-Free Testing for Acute Toxicity” 2016
217 OPTIMIsE Commercial feasibility of the Novio-PlainGel: a novel synthetic, reversible thermosensitive, biomimetic hydrogel for organoid-based precision medicine 2016
218 StemProteostasis Mediation of stem cell identity and aging by proteostasis 2016
219 HepatoMetaboPath Cellular and molecular mechanisms of metabolic immune activation triggering non-alcoholic steatohepatitis (NASH) and HCC 2016
220 PyroPop Mechanisms and regulation of inflammasome-associated programmed cell death 2017
221 Immune-senescence Dual targeting of senescence and tumor immunity for cancer therapy 2016
222 Totipotency Transcriptional and Epigenetic Regulation of Totipotency in Mouse Early Embryos. 2016
223 DENDRITECIRCUITS The origins of dendritic computation within mammalian neural circuits 2016
224 NEUROMET Shaping of axonal complexity by a dynamic regulation of local metabolic pathways in the developing cortex 2016
225 NEWRON New and mature neurons in adult circuits: telling memories apart 2016
226 INVADIS Microbial invasion and dissemination within the host, mechanisms and effects 2016
227 ACoolTouch Neural mechanisms of multisensory perceptual binding 2016
228 BCM-UPS Dissecting the role of the ubiquitin proteasome system in the pathogenesis and therapy of B-cell malignancies 2016
229 PROVASC Cell-specific vascular protection by CXCL12/CXCR4 2016
230 Descent Control of Action Diversification by Descending Motor CircuitsControl of action diversification by descending motor circuits 2016
231 MEDICI The inflammatory gene expression program in macrophages: An integrative approach for the systematic characterization of transcriptional co-regulators 2016
232 NMDADYN NMDA receptor diversity: from molecular dynamics to synaptic physiopathology 2016
233 LocomotorIntegration Functional connectome of brainstem circuits that control locomotion 2016
234 COREMA Cell division and the origin of embryonic aneuploidy in preimplantation mouse development 2017
235 TNT-TUMORS Therapeutic approaches to enhance innate immunity against Tumors 2016
236 INTEGRAL Signal Integration by Gene Regulatory Landscapes 2016
237 ILC_REACTIVITY Biological Determinants of ILC Reactivity for Immune Responses in Health and Disease 2016
238 SYNNOVATE Molecular organization and dynamics of synapse diversity: novel genetic, imaging and computational approaches 2016
239 RULLIVER Rules of self-organization and reengineering of liver tissue 2016
240 iPSCAtaxia An induced pluripotent stem cell-based neuronal model of Spinocerebellar ataxia 2016
241 GBM-CPP Developing an anti-Myc cell-penetrating peptide for cancer treatment 2016
242 LSDiASD Leveraging Small Demethylase inhibitors for Autism Spectrum Disorder 2016
243 AD-VIP Alzheimer’s disease and AAV9: Use of a virus-based delivery system for vectored immunoprophylaxis in dementia. 2016
244 ASSIMILES Advanced Spectroscopy and Spectrometry for Imaging Metabolism using Isotopically-Labeled Endogenous Substrates 2016
245 MATRICAN Matrix during cancer progression 2016
246 B-response Memory and innate-like B-cell subsets: deciphering a multi-layered B-cell response in mice and humans 2016
247 TransSplicHD Single-Cell Transcriptomics and Spliceosome analysis to uncover new mechanisms of neuronal vulnerability to Huntington’s Disease. 2016
248 Neobetacell Neogenesis of new functional Beta Cells through Modulation of Neurogenin-3 Expression to provide Regenerative Therapy for Diabetes Patients 2016
249 TRANSREAD Restoration of tumor suppressor function by induction of translational read-through of premature termination codons - a strategy for improved cancer therapy 2016
250 OOCSOCS Socs3 gene in oocyte maturation and fertilisation - a novel link between inflammation and infertility 2017
251 BRCANCER A novel approach for modeling development of breast cancer 2016
252 4DHeart 4D analysis of heart development and regeneration using advanced light microscopy 2017
253 PAIN-Net Molecule-to-man pain network 2017
254 circRTrain circular RNA Biology Training Network: from biogenesis to biomarkers 2017
255 ORCHESTRATE Building complex life through self-organization: from organ to organism 2016
256 MacAGE Macrophage aging and rejuvenation 2017
257 Neurogenesis Exploration and promotion of neurogenesis in the adult brain 2016
258 EMODI Epithelial resistance modulation to treat disease 2016
259 MultimodalCellTrack Multimodal preclinical imaging probes to evaluate the safety and efficacy of regenerative medicine therapies 2016
260 RTEL1inHHS Characterization of RTEL1 mutations in Hoyeraal-Hreidarsson Syndrome 2017
261 SEMA3C Genetic dissection of the SEMA3C/Neuropilin 1 signalling pathway in Chronic Kidney Disease progression 2016
262 EXNADMINA EXercise as a regulator of hepatic NAD metabolism and MItochondrial function in Non-Alcoholic fatty liver disease 2016
263 ACENTSPINTUB Setting up the spindle in the mammalian egg for meiosis and embryo development 2017
264 LysoMod Genetic and Small Molecule Modifiers of Lysosomal Function 2017
265 BrainBIT All-optical brain-to-brain behaviour and information transfer 2016
266 Diet-namic From fast food to healthy diet: Addressing the dynamic molecular mechanism of sequential diet switch-induced T cell plasticity for the purpose of developing new treatments for immuno-mediated diseases 2016
267 CD40-INN CD40 goes innate: defining and targeting CD40 signaling intermediates in the macrophage to treat atherosclerosis 2016
268 TILC Targeting Innate Lymphoid Cells 2017
269 IntegraMouse3 Next-generation, modular computer mouse device for disabled people 2016
270 MUC2GO THE ROLE OF MUCINS AND MUCUS IN THE DISEASES CYSTIC FIBROSIS, CELIAC DISEASE, AND ULCERATIVE COLITIS 2016
271 GUTPEPTIDES Novel therapeutic approaches to improve gastrointestinal wound healing 2017
272 MitoMethylome Mitochondrial methylation and its role in health and disease 2017
273 RAPID Chromatin dynamics resolved by rapid protein labeling and bioorthogonal capture 2017
274 CAVEHEART Heart regeneration in the Mexican cavefish: The difference between healing and scarring 2017
275 MECHANO-CONTROL Mechanical control of biological function 2017
276 OVOMATIC IN-OVO AUTOMATION FOR CANCER DRUG DISCOVERY 2017
277 BETA-BACT Beta-cell inflammation and dysfunction induced by bacterial translocation 2016
278 BONEPHAGY Defining the role of the FGF – autophagy axis in bone physiology 2017
279 INFRAFRONTIER2020 Towards enduring mouse resources and services advancing research into human health and disease 2017
280 HISTO-MRI IN SITU IMAGING OF LIVING TISSUES WITH CELLULAR SPATIAL RESOLUTION 2017
281 EVOLVE Extracellular Vesicle-Internalizing Receptors (EVIRs) for Cancer ImmunoGeneTherapy 2017
282 GLYCONEOBRAIN Exploring glycosidic neo-epitopes of degenerative hippocampal granules in aged mice and humans: implications for ageing and dementia 2017
283 CFED Unravelling the mechanisms regulating cellular fitness during embryonic development 2017
284 IMMUNE CELL SWARMS Innate Immune Cell Swarms: Integrating and Adapting Single Cell and Population Dynamics in Inflamed and Infected Tissues 2017
285 MetResistance The role of tumour microenvironment in metastatic hormone-refractory prostate cancer 2017
286 STIMUNITY Preclinical validation of a novel immunogenic composition to stimulate innate immunity 2017
287 NEW-AGE A next-generation platform for catalysing pre-clinical development of drugs against Alzheimer’s and other degenerative diseases of old-age 2017
288 COLGENES Defining novel mechanisms critical for colorectal tumourigenesis 2017
289 FungArth Role of intestinal fungal communities in arthritic pathology 2017
290 BRECASTEM Functional and Molecular Characterisation of Breast Cancer Stem Cells 2017
291 VestibVis Visual and vestibular processing in secondary visual cortex 2017
292 Mitomorphosis Metabolic regulation of mitochondrial morphology 2017
293 INVESTIGERFE Investigating the regulation of iron homeostasis by erythroferrone and therapeutic applications 2017
294 3DQuant Understanding long-range transcriptional regulation in the context of the 3D genome organization 2017
295 eWAD Unbalanced Wnt signalling in AD: a DNA methylation effect 2017
296 ConCorND Connectivity Correlate of Molecular Pathology in Neurodegeneration 2017
297 CHROMONUMBER Chromosome number variations in vivo: probing mechanisms of genesis and elimination 2017
298 Lightsheetelegans In-toto imaging of C. elegans larval development using adaptive optics light-sheet microscopy 2017
299 Schizo-EPICOG Inflammatory processes underlying cognitive deficits in schizophrenia: epigenetic mechanisms and pharmacological regulation 2018
300 IndiVISUAL Role of individual retinal ganglion cell types in visual computation and behaviors 2018
301 RSCHD Functional dissection of the head-direction circuit in mouse retrosplenial cortex. 2017
302 PHYSBIOHSC Understanding the physical biology of adult blood stem cells 2017
303 MetEpiStem Dissecting the crosstalk between metabolism and transcriptional regulation in pluripotent stem cells. 2017
304 SynID Activity-dependent modulation of synapse identity 2017
305 DREMATURE DNA repair mechanisms and therapy resistance of BRCA2-deficient cancers 2018
306 SupaSteD Suppresion of adaptive immunity by the Salmonella effector SteD 2017
307 MitoDyaD The role of the glucocorticoid receptor in dopaminoceptive neurons in mitochondrial dysfunction and vulnerability to depression 2017
308 DIRECtA Targeting the Endocannabinoid System within Islets of Langerhans to Protect against Immune Destruction. 2018
309 DNAmethAML Investigation of aberrant DNA methylation in malignant haematopoiesis 2018
310 MSCFate Fate of mammary stem cells during tumorigenesis and clinical implications 2017
311 HeartATAC Epigenetic regulation of cardiac regeneration after injury. 2017
312 NanoALS Nanoparticle-based immunization, a novel therapeutic strategy for amyotrophic lateral sclerosis 2018
313 RANdOM Systematic search of RegulAtory elements coNtrOlling autosomal Monoallelic expression 2018
314 DNCSS Decoding neural circuits controlling sleep drive and sedation 2018
315 MetaBiota Crosstalk between microbiota metabolites and immune cells, the missing link to brain damage. 2017
316 iChip Intestine-on-a-chip for investigating microbioal-epithelail interaction 2018
317 ChromoDrive Investigating how anaphase chromosomal motion is generated during mitosis and meiosis 2017
318 TeloChromatin Dissecting the chromatin dynamics at telomeres during mouse pre-implantation development. 2017
319 IVORIaN RAS/C-RAF interaction: A new pharmacological target in Kras-driven lung cancer. 2017
320 TISSUENEU Role of infiltrating neutrophils in tissue homeostasis 2017
321 PhotoNanoBone Photoresponsive Smart Nanocarriers for Tetherless Regeneration of Bone Tissue 2018
322 GaMePLAY Gut microbiota impact on brain development and plasticity. 2017
323 MOBER Maternal Obesity and Epigenetic Reprogramming: from Gametogenesis to Early Embryonic Development 2017
324 Immunometabolomics CD8+ T cell metabolism in anti-tumor response 2017
325 NEURO_NMD Functional impact of alternative splicing coupled to nonsense-mediated decay in developing neurons 2017
326 METMEL Long range-acting drivers of premetastatic niches in melanoma 2017
327 CODE4Vision Computational Dissection of Effective Circuitry and Encoding in the Retina for Normal and Restored Vision 2017
328 CD4CRISPR A quorum sensing mechanism regulating CD4 T cell proliferation 2017
329 MEMORIS Maternal Enteric Microbiota for Offspring's Repertoire development and Illness Susceptibility 2018
330 3DMUCHO Investigation of 3D Functional Connectivity in Mouse Visual Cortex using Holography and Optogenetics 2017
331 VWF and NETs Investigating the interplay between VWF, platelets, and neutrophil extracellular traps in pathologies involving thrombosis of the microvasculature 2017
332 MUC The microbial degradation and utilization of mucin by Bacteroides in ulcerative colitis 2017
333 MeGa DNA Methylation dynamics during Gastrulation 2018
334 EpiPur The ATP-P2X7R axis: a target for drug-refractory epilepsy 2018
335 Hepatocarcinoma IVM Spatiotemporal dynamics of CD8+ T cell responses to hepatocellular carcinoma 2017
336 UVdynamicsProtection Aligning pigmentation and repair: a holistic approach for UV protection dynamics 2017
337 EpiRetention Mechanisms of selective transmission of epigenetic marks through the male germ line 2017
338 BaskAtax Modulation of Basket cell microcircuits in cerebellar cortex paroxysmal ataxia disorders 2017
339 MITOMAD Functional characterisation of mitochondrial metabolic adaptations to innate sensing in dendritic cell subsets 2017
340 RepTime Molecular control of DNA replication timing in mammalian cells 2017
341 ESCAPE_COPD Elimination of Senescent Cells Approach for treatment of COPD 2017
342 EpiTrack Single-cell temporal tracking of epigenetic DNA marks 2017
343 INTUMORX Elucidation of intratumoral heterogeneity in Kras-driven cancers 2017
344 METACHROM Establishment and maintenance of gene expression by heterochromatin factors 2017
345 CellTrack Cellular Position Tracking Using DNA Origami Barcodes 2017
346 REPRODAMH Extra-gonadal roles of Anti-Müllerian Hormone in the aetiology of polycystic ovary syndrome: the domino effect to reproductive neuroendocrine dysfunctions 2017
347 EpiFAT Epigenomic Reprogramming of Adipose Tissue Function and Energy Metabolism in Type 2 Diabetes 2017
348 CORFEDITING Gene Editing as Therapeutic Strategy for C9ORF72 Linked ALS/FTD 2017
349 SIRMIO Small animal proton Irradiator for Research in Molecular Image-guided radiation-Oncology 2017
350 NAFLDcure A novel pharmaceutical treatment for nonalcoholic fatty liver disease 2017
351 BARCODED-CELLTRACING Endogenous barcoding for in vivo fate mapping of lineage development in the blood and immune system 2017
352 PRELICAN Treatment of liver disease and cancer prevention 2017
353 ITCC-P4 ITCC Pediatric Preclinical POC Platform – Sofia ref.: 116064 2017
354 KupfferCellNiche Determining the instructive tissue signals and the master transcription factors driving Kupffer cell differentiation 2017
355 ImmuneCheckpointsAD Immune checkpoint blockade for fighting Alzheimer’s disease 2017
356 FATE Functional Biology of Hepatic CD8+ T cells 2017
357 DissectPcG Dissecting the Function of Multiple Polycomb Group Complexes in Establishing Transcriptional Identity 2017
358 OVO-GROWTH Oogenesis spotlighted: making mature human oocytes 2017
359 ENLIGHTEN INTEGRATION AND PROPAGATION OF IMMUNOLOGICAL SIGNALS DURING CANCER AND INFECTION 2018
360 mtDNA-CURE Treating mitochondrial disease caused by pathogenic mtDNA mutations 2018
361 NEMESIS Neuron/mast cell interactions in skin diseases 2017
362 MechAGE In Vivo Single-Cell Mechanomics of Bone Adaptation and Regeneration in the Aging Mouse 2017
363 PainCells Decomposition of pain into celltypes 2017
364 scAssembly Algorithms and experimental tools for integrating very large-scale single cell genomics data 2017
365 SYNEME Systems Neuroscience of Metabolism 2017
366 VOLSIGNAL Volume regulation and extracellular signalling by anion channels 2017
367 CartiLube Lubricating Cartilage: exploring the relation between lubrication and gene-regulation to alleviate osteoarthritis 2017
368 BrainDrain Translational implications of the discovery of brain-draining lymphatics 2017
369 V-EPC Inherited disfunctions of brain microcirculation 2017
370 DeAge Deconstructing Ageing: from molecular mechanisms to intervention strategies 2017
371 PD UpReg Gene knock-up via 3’UTR targeting to treat Parkinson’s disease 2017
372 Dam2Age DNA Damage and Repair and its Impact on Healthy Ageing 2017
373 SelforganisingEmbryo Self-organisation across the scales in early mammalian development 2017
374 Daphne Circuits of Visual Attention 2017
375 CINCHRON Comparative INsect CHRONobiology 2018
376 WhiskTrackGP Real-time tracking of whisker kinematics for closed-loop neuroscientific experiments 2017
377 StroMaP Stromal stress networks underlying phenotypic plasticity and tumor fitness 2017
378 deFIBER Dissecting the cellular and molecular dynamics of bone marrow fibrosis for improved diagnostics and treatment 2018
379 RetinalRepurposing Deciphering the computations underlying visual processing: Repurposing of retinal cells and how they are decoded by the visual thalamus 2017
380 TRIPLECON Triple negative breast cancer control through synergistic inhibition of EGFR and CDK9 signaling 2017
381 InsularAnxiety Insular cortical circuits controlling fear and anxiety 2018
382 FAITh Fighting Anxiety with Importin-based Therapeutics 2017
383 CELLNAIVETY Deciphering the Molecular Foundations and Functional Competence of Alternative Human Naïve Pluripotent Stem Cells 2017
384 TREAT-NPM1-AML Improving therapy of NPM1-mutated AML 2017
385 CSI-Fun Chronic Systemic Inflammation: Functional organ cross-talk in inflammatory disease and cancer 2018
386 MoThal Functional exploration of the contributions of brainstem-motor thalamic pathways to motor execution and learning 2018
387 AstroNeuroCrosstalk Astrocyte-Neuronal Crosstalk in Obesity and Diabetes 2018
388 ELONGAN Gene editing and in vitro approaches to understand conceptus elongation in ungulates 2017
389 EDIReX EurOPDX Distributed Infrastructure for Research on patient-derived cancer Xenografts 2018
390 NO-STRESS Nitric oxide regulation of repolarisation in the heart: role of mechanical stress 2018
391 UshTher Clinical trial of gene therapy with dual AAV vectors for retinitis pigmentosa in patients with Usher syndrome type IB 2018
392 MCDS-Therapy Repurposing of carbamazepine for treatment of skeletal dysplasia 2017
393 ELIMINATE Development of strategies to eliminate cancer cells from the bone marrow 2018
394 CANCER-DC Dissecting Regulatory Networks That Mediate Dendritic Cell Suppression 2018
395 AltCheM In vivo functional screens to decipher mechanisms of stochastically- and mutationally-induced chemoresistance in Acute Myeloid Leukemia 2018
396 CESYDE Ceramide Synthases in Diabetic Beta Cell Demise 2018
397 STRATO Stress as a modifier of atherosclerosis - Novel mechanistic insights and therapeutic avenues - 2018
398 DualRP Exploring cell interactions in the tumor microenvironment with dual ribosome profiling 2018
399 MASTFAST Rapid production of HUMAN MAST CELLS 2017
400 CANCER Personalised Postoperative Immunotherapy To Improving Cancer Outcome and improving quality of life 2018
401 Signa2.0 Signaturit 2018
402 ITHACA Immuno-targeting of human AML quiescent cells by a novel phage display approach. 2018
403 Easy Reading Easy Reading: A Framework for Personalised Cognitive Accessibility when using Original Digital Content 2018
404 N-IF The N-IF mouse – a new and unique fibrosis model for preclinical efficacy studies 2017
405 MECHABLASTO Morphogenesis during pre-implantation development: molecular and mechanical regulation 2018
406 Damocles Modelling brain aneurysm to elucidate the role of platelets 2018
407 LSO Liver Spatial Omics 2018
408 CMTaaRS Defective protein translation as a pathogenic mechanism of peripheral neuropathy 2018
409 SysOrganoid A systems biology approach to investigate cell fate switches in intestinal organoids 2018
410 REBUILDCNS Redirecting glial progenitor fate to rebuild the injured Brain 2018
411 BTech Novel human neurodegenerative disease specific 3D cell-models with applications in drug development and toxicity testing 2018
412 MetaRegulation Metabolic regulation of metastatic growth 2018
413 YinYang Hypothalamic circuits for the selection of defensive and mating behavior in females 2018
414 ImmunoFit Harnessing tumor metabolism to overcome immunosupression 2018
415 HIV B Cell Function Understanding HIV-specific B cell function and viral immunogenicity 2018
416 CLAUSTRUM The Claustrum: A Circuit Hub for Attention 2018
417 CALLAX What is the role of the axonal connections between the hemispheres in sensory processing? 2018
418 LYSOBONE Cellular and molecular analysis of the skeletal pathologies associated with mucopolysaccharidosis-VI (MPS-VI) 2018
419 MouseDepthPrey The role of depth perception during prey capture in the mouse 2018
420 BinD Mitotic Bookmarking, Stem Cells and early Development 2018
421 Alpha-Synuclein Blocking the prion-like disease propagation in Parkinson’s disease and related disorders – model development and identification of cell-autonomous and cell non-autonomous factors. 2019
422 IRONAGE Iron as a driver of fibrosis and regeneration 2018
423 NEUROGUIDE Study of neuronal sensing and migration/guidance dynamics in neurodevelopmental disorders by nano-engineered chips 2018
424 BRONC Behavioral demand-driven dynamic reorganisation of cortical networks revealed by simultaneous wide-field optical imaging and optogenetic stimulation mapping in task-performing mice 2018
425 INTEREP Do cortical feedback connections store statistical knowledge of the environment? 2018
426 DUX4 Function of DUX4 in skeletal muscle and non-muscle tissues 2018
427 EnCAge Progeria models to study endothelial cell ageing: implications for organ regeneration and fibrosis 2020
428 FatTryp Exploring the hidden life of African trypanosomes: parasite fat tropism and implications for disease 2018
429 Reprogram-Diabetes In vivo drug discovery for cellular reprogramming to β-cells – towards a future regenerative therapy for diabetes 2018
430 UB-RASDisease The ubiquitin system in RAS-driven disease 2018
431 ANTILEAK Development of antagonists of vascular leakage 2018
432 VALSL Valorisation of splice-switching oligonucleotides for lung cancer therapy 2018
433 Target5LO Targeting 5-lipoxygenase in the context of Acute Myeloid Leukemia 2018
434 TREGinAD Role of Aβ Specific Regulatory T cells in harnessing cerebral Aβ clearance in Alzheimer’s Disease 2018
435 IVSTED In vivo super-resolution imaging of synapses in the hippocampus 2019
436 VOLIV Role of volume-regulated anion channels in liver physiology and metabolism 2019
437 CORVISDEC Cortical circuits underlying visual decision-making behaviors in mice 2018
438 SOCIALBRAINCIRCUITS Neuroanatomical substrates of social deficit in a mouse model of 22q11 deletion syndrome 2018
439 MECEDGE Transgenic dissection of the neural circuitry of memory and dementia 2018
440 H2Gut Interspecies hydrogen transfer in the mammalian gut: how interactions between fermenters and hydrogenotrophs influence colonic homeostasis 2018
441 MITOPOMPE Targeting mitochondrial defects and oxidative stress in Pompe Disease: from pathogenesis to therapy 2019
442 FIBROSIS Fibroproliferative Invasive Fibroblasts in Idiopathic Pulmonary Fibrosis 2018
443 GLIAMAC Uncovering Enteric GLIA-MACrophage communication in the intestinal homeostasis and inflammation 2018
444 Striking streaks Invariant Natural Killer T-cells in atherogenesis 2018
445 INFLA-AID The role of NLRC4 inflammasome in autoinflammatory diseases 2018
446 EpiNoise The role of epigenetic heterogeneity in cell fate decisions 2019
447 MECHANOSITY Mechanical regulation of cellular behaviour in 3D viscoelastic materials 2019
448 ProLung The role of maternal microbiota in offspring lung development and function 2019
449 UNNAMEd-2 Unraveling the conceptional novel ADAM17 regulation by PP2A in metastasis formation. 2019
450 MAGIC Magnification of Asthma by human memory Group 2 Innate lymphoid Cells 2018
451 KILNEV Killing Senescent Cells as a Novel Method to Eliminate Nevi 2018
452 NINTCORDEV NIPBL and Integrator function and dysfunction in human cortical development 2018
453 MECHPREDPRO Cellular mechanisms of predictive processing and its effects on perception 2018
454 PerMet Role of peroxisomal fatty acid β-oxidation in vessel sprouting 2018
455 NEVULA Understanding selective neuronal vulnerability in Alzheimer’s disease 2018
456 HDAC6_GEMM Development of a novel genetically engineered mouse model to study the role of HDAC6 in oncogenesis and metastasis of non-small cell lung cancer. 2018
457 SKin SCiENCE Skin Keratinocyte Stem CEll proliferatioN in field CancErisation 2018
458 GDCOLCA Understanding gamma delta T cells in colon cancer metastasis 2018
459 TAMYOCAL Tamoxifen mediated protection on X-linked centronuclear myopathy: a mechanistic and pre-clinical study 2018
460 HUMANITY Human Lung Microbiota And Innate Immunity 2019
461 TakeupSLaCk Role and regulation of dendritic cell functions by Solute Carrier Transporters 2019
462 MATURE-NK MAnufacturing of TUmour-REactive Natural Killer cells 2018
463 GENOMIA Genomic Modifiers of Inherited Aortapathy 2019
464 DCPOIESIS Steady-state and demand-driven dendritic cell generation 2018
465 IntraGutSex Sex differences in intestinal plasticity 2018
466 MicroWars The Evolution of Bacterial Warfare 2018
467 mTORmorS Role of mTOR signaling dysregulation in the tumor suppressor networks in hepatocellular carcinoma 2019
468 Huntingtin hPSC Unraveling huntingtin function in cortical and striatal human development 2018
469 EVO-NANO Evolvable platform for programmable nanoparticle-based cancer therapies 2018
470 TALVIN Inhibiting mechanotransduction for the treatment of pancreatic cancer 2018
471 E-T1IFNs Elaboration of the type I interferonopathies 2018
472 AbCURE_COPD Antibody mediated clearance of senescent cells for treatment of COPD 2018
473 DEEPEN Deciphering deep architectures underlying structured perception in auditory networks 2018
474 PCAPIP Towards understanding non-canonical phosphatidylinositol kinases in the maintenance of prostate metabolism. 2018
475 SYST-iMYC Development of an effective and safe systemic Myc inhibitor for the treatment of multiple cancer types. 2018
476 NeuroProtect Novel Drug Therapy with Potential to Cure Neuro-Degenerative Diseases 2018
477 2shRNA 2shRNA branched nanobinders as promising therapeutic tools for combined cancer therapy 2019
478 NEVADA Novel microengineered environments for mouse embryonic stem cell (mESC) differentiation towards cardiomyocytes 2018
479 STARNEL supracellular contractility of myofibroblasts in gut homeostasis and cancer invasion 2018
480 Treat-HSP Development of new therapy for rare motor neuron diseases 2018
481 FitteR-CATABOLIC Survival of the Fittest: On how to enhance recovery from critical illness through learning from evolutionary conserved catabolic pathways 2018
482 EPI-X4Health Therapeutic potential of optimized derivatives of an endogenous CXCR4 antagonist for the treatment of cancers and inflammatory diseases 2018
483 PROVEC Promoting Osteogenesis through Vascular Endothelial Cells 2019
484 GIDE Molecular diversification of inhibitory neurons during development 2019
485 pHioniC pH and Ion Transport in Pancreatic Cancer 2018
486 COR1-TCELL Analysis of the role for coronin 1-dependent cell density signalling in T-cell homeostasis 2019
487 DiRECT Directly reprogrammed renal cells for targeted medicine 2019
488 VITAE VIrTual BrAin PErfusion: Assessing cerebrovascular function by High Performance Computing from 3D brain vessel network data for vascular-targeted drug development in neurodegenerative diseases. 2018
489 REMIND Targeting pathological synaptic pruning by microglia in neurodegeneration 2019
490 PedSarc Targeting genetic and epigenetic mechanisms in pediatric sarcomas. 2019
491 CuRE Cardiac REgeneration from within 2019
492 MegaALS Unravelling the Interplay between Metabolism, Gut Microbiome and Adaptive Immunity in Amyotrophic Lateral Sclerosis 2018
493 LeukemiaEnviron SIGNALING PROPENSITY IN THE MICROENVIRONMENT OF B CELL CHRONIC LYMPHOCYTIC LEUKEMIA 2019
494 SYNPATH Regulation of synaptic development and plasticity by molecular pathways linked to human evolution 2019
495 METANICHE Regulation of bone metastases by age-associated angiocrine signals 2019
496 DisConn Neural drivers of functional disconnectivity in brain disorders 2019
497 IMMCEPTION Nociception and sensory nerves as regulators of type 2 immunity and skin inflammation 2019
498 BARINAFLD Using Bariatric Surgery to Discover Weight-Loss Independent Mechanisms Leading to the Reversal of Fatty Liver Disease 2018
499 SafeFate Safeguarding Cell Fate by Terminal Repression during Development and Disease 2019
500 STICK2HEAL Innovative adhesives for ear drum healing 2019
501 PrefrontalMap Organization and learning-associated dynamics of prefrontal synaptic connectivity 2019
502 BRITE Elucidating the molecular mechanisms underlying brite adipocyte specification and activation 2019
503 WATCH Well-Aging and the Tanycytic Control of Health 2019
504 PRinTERs Post-transcriptional regulation of effector function in T cells by RNA binding proteins 2019
505 EngineeringBAP Engineering brain activity patterns for therapeutics of neuropsychiatric and neurological disorders 2019
506 ImmuNiche Identifying spatial determinants of immune cell fate commitment 2019
507 MADEFUN Regulation of Brain Macrophage Development and Function 2019
508 ADIMMUNE Decoding interactions between adipose tissue immune cells, metabolic function, and the intestinal microbiome in obesity 2019
509 iHEAR Gene therapy of inherited and acquired hearing loss 2019
510 SCHIZTYPE Brain cell type-specific interactions and schizophrenia 2019
511 PACA-MET Genome-wide surveys and functional analysis of pancreatic cancer metastasis drivers 2019
512 ONCOFUM Integrating the tissue-specificity and chronology of hereditary renal cancer predisposition 2019
513 ScarLessWorld A WORLD WITHOUT SCARS: Regenerating wounded skin rather than patching with scars 2019
514 Cluster-Buster Development of small molecule inhibitors of circulating tumor cell clusters 2019
515 IntratumoralNiche Defining heterocellular signalling within the intratumoral stem cell niche of colorectal cancer 2019
516 ReCoDE Reshaping cortical circuits to decrease binge eating 2019
517 CRC-MTOs Colorectal Cancer Mouse Tumor Organoids as Pre-clinical Models for Therapeutical Testing 2018
518 skILL Intracellular signalling by modified lipopolysaccharide 2019
519 ChaperoneRegulome ChaperoneRegulome: Understanding cell-type-specificity of chaperone regulation 2020
520 INHuMAN Intra-tumoral heterogeneity in NRAS-driven metastatic melanoma 2019
521 IRF4 Degradation Using a novel protein degradation approach to uncover IRF4-regulated genes in plasma cells 2019
522 IDENSTEM Identification and characterization of enteric nervous system stem cells 2020
523 RoBE Study of the role of BANK1 in antibody production and antibody-independent functions of B cells in SLE 2019
524 Kinaddict Vulnerability of esophageal cancer to their addiction to kinase activities: evaluation and prediction of eSCC tumors responsiveness to kinase inhibitors. 2019
525 RESIST3D Targeting drug resistance in ovarian cancer through large-scale drug-response profiling in physiologically relevant cancer organoids 2020
526 GlyCANswer Decoding the Cancer Glycoproteome Driven Immune Response 2019
527 R-FunSel In vivo functional screening via CRISPR-Cas9 to systematically identify cardiomyocyte receptors as targets for the innovative therapies for myocardial infarction and heart failure 2019
528 CApaCITy CAncer Stem Cell Imunoreceptors as potential Targets for skin Squamous cell carcinoma 2019
529 SyLeNCe Synapses between Leukaemia and its Neighbouring Cells 2020
530 NanoMechShape Molecular control of actin network architecture and mechanics during cell shape changes 2019
531 MacrophInt Targeting integrin signaling in tumour-associated macrophages to combat cancer progression and resistance 2019
532 DECOMPACT Development of Collagenase Polymeric nanocapsules as Therapeutics 2019
533 MechaPattern Coordination between cell identity, tissue mechanics and proportionate patterning during vertebrate eye formation 2019
534 SUBNETVIS Identifying subtype specific networks involved in sensory representation in mouse primary visual cortex 2020
535 uTSSreg Regulation of mammalian genes by new classes of promoter proximal transcription start sites 2020
536 CentrosoTME The role of extra centrosomes on the tumour microenvironment 2019
537 MetaTarGet Targeting metabolic regulation in metastasis formation 2019
538 eBAT Enhancing brown adipose tissue through NAD+ precursors: a new approach to treat cardiometabolic disease 2019
539 STRomA Novel Matrix Stiffness-regulated Genes in Lymphangiogenesis and Angiogenesis 2019
540 PanILC Deciphering type 2 innate lymphoid cell/epithelial progenitor cell crosstalk in pancreas regeneration and neoplasia 2019
541 FUSEDESIGN Model-guided design of a stabilized pre-fusion class III viral fusogen, rabies virus glycoprotein 2019
542 InvADeRS Investigating the Activity of transposon Derived Regulatory Sequences in the placenta 2019
543 META2 METAbolism of bone METAstasis (META2): Metabolic interactions between disseminated breast cancer cells and osteoblast lineage cells drive bone metastases formation 2019
544 CRISPR-KissCas9 Challenging the KNDy Hypothesis Using CRISPR-Cas9 Genome Editing: Evaluation of the Role of Neurokinin B and Dynorphin in Kiss1 neurons in the Control of Fertility 2020
545 H2AH2B_Propagation Elucidating the propagation and function of H2A and H2B modifications across DNA replication 2020
546 AstroCOMET Astrocyte-neuron COmmunication in METabolism and obesity. 2020
547 STIMOS Stimulation of Multiple Organoids Simultaneously 2019
548 PMLingAML Using PML nuclear body biology to identify potential AML treatment targets 2020
549 NeuroSens Neuromodulation of Sensory Processing 2019
550 Grolaries Cartilage progenitor cells for growth plate regeneration 2019
551 GUTPOLAR Membrane trafficking as a link between cell polarity and intestinal absorptive function: from C. elegans to mammalian miniguts 2019
552 FOFC Function and Organization of Feedback Connections 2019
553 Food-PPP-NAFLD Discovery and characterization of food bioactive compounds modulating the Pentose Phosphate Pathway against non-alcoholic fatty liver disease. 2019
554 BRAIN-MATCH Matching CNS Lineage Maps with Molecular Brain Tumor Portraits for Translational Exploitation 2019
555 MiniEmbryoBlueprint The mammalian body plan blueprint, an in vitro approach 2019
556 NEUROSKIN Modulating skin innervation to treat cutaneous inflammation 2019
557 ReproXimera Modelling in vivo lineage reprogramming of human astrocytes into induced neurons in the adult mouse brain 2020
558 FEN INHIBITORS Development of Kinetoplastida Flap Endonuclease Inhibitors in Search for Novel Therapeutics 2020
559 TargetGBM Generating a targeted, brain-permeable and stable polymeric nanoparticle for systemic gene delivery to glioblastoma 2019
560 NeuroFreezing Biophysical Properties of the Neuronal Cytosol and their Dynamics upon Nutrient Starvation, Aging, and in Neurodegenerative Diseases. 2019
561 DEAP Development of Epithelium Apical Polarity: Does the mechanical cell-cell adhesions play a role? 2019
562 LongPlaNet Long-Range Plasticity of Neuronal Networks in the Adult Brain 2019
563 3DConfigurator Fully-automated software platform with 3D freeform configurator for design and production of individual and affordable furniture 2019
564 B-different The RNA-Binding Protein ZFP36L1 regulates the terminal differentiation of B lymphocytes 2020
565 QuiescStemGBM Studying the role of Quiescent Cancer Stem Cells in GBM development using a novel in vivo cell cycle-based approach 2020
566 CAN-IT-BARRIERS Disruption of systemic and microenvironmental barriers to immunotherapy of antigenic tumors 2020
567 PROTEUS Predicting Routes Of Tumour Evolution driven by Unstable genomes and Selection 2019
568 mAMBo The role of ASCL1 and MYCN in human brain development 2019
569 CHyMERA Monitoring cancer heterogeneity based on the dynamic assessment of the Warburg effect under metabolic perturbation 2019
570 CANSAS Clustering functional connectivity alterations in Autism Spectrum Disorders 2020
571 MADMpancreas Using the precision mouse genetic tool MADM to elucidate the role of EGFR in directing beta cell differentiation and pancreatic morphogenesis 2019
572 His-Li mouse His-Li mouse, the unique humanized mouse model resembling human liver and immune systems 2019
573 SCOPE Schwann Cell Options for chronic Pain Eradication 2019
574 Healthybiota Microbiota-host interactions for integrative metabolic health reprogramming 2019
575 Genetic Vaccine Study the therapeutic and preventive potential of targeting oncogenic mutations with CRISPR-Cas9 technology 2019
576 ADAPT2FLOW Adaptive and maladaptive endothelial cell dynamics during blood flow-driven vascular patterning 2019
577 GENESIS unveilinG cEll-cell fusioN mEdiated by fuSexins In chordateS 2020
578 UNPACK PD-L1 Molecular mechanism and inhibition of extracellular vesicle-mediated PD-L1 release in melanoma cells 2020
579 MS Unravelling the molecular and cellular mechanism of metastasis 2020
580 MOVEMeNt Decoding alpha motor neurons diversity and selective vulnerability to disease 2020
581 BreakingBarriers Targeting endothelial barriers to combat disease 2019
582 VACCIBIOME Cancer Vaccines and Gut Microbiome: a rational approach to optimize cancer immunotherapy 2019
583 Anti-L1CAM Anti-L1CAM antibody: A novel efficacious immunotherapy for pancreatic and ovarian cancer patients 2019
584 FunStructure Interdependence of functional and structural plasticity in cerebellar climbing fibers in health and disease 2019
585 RASImmune Targeting RAS driven tumour immune evasion 2019
586 ARCH AGE-RELATED CHANGES IN HEMATOPOIESIS 2019
587 REPLAY_DMN A theory of global memory systems 2019
588 CONNECT-2-CLINIC Pannexin1 nanobodies for the clinical treatment of liver disease 2020
589 CRESCENT CRESCENT: Adaptive hands-free controller for people with disabilities 2019
590 CANCERPREV Innovative strategies for cancer prevention with focus on sex hormone signaling and chronic inflammation 2019
591 SAND Secretion, Autophagy and their role in Neurodegeneration 2019
592 NEUROPA Non-invasive dynamic neural control by laser-based technology 2020
593 EmbryoMethFunc Cell-Type Specific DNA Methylation Changes During Mammalian Development: Beyond Mapping 2019
594 ADAMtx ADAMtx: Development of Alzheimer’s immunotherapy by harnessing the natural reparative properties of microglia 2019
595 GuMeCo Gut-Brain Communication in Metabolic Control 2020
596 INFANT MEMORIES Dissecting hippocampal circuits for the encoding of early-life memories 2020
597 sociOlfa Learning from social scents: from territory to identity 2020
598 DyNAmecs Early embryonic events, life-long consequences: DNA methylation dynamics in mammalian development 2020
599 ANIMATE Adaptive Immunity in Human Atherosclerosis: Understanding its Cellular Basis to Define Novel Immunomodulatory Therapies 2020
600 ChronicPain New Target and Drug Candidates for Alleviating Chronic Pain 2019
601 SynLink Molecular Structure and Engineering of Synaptic Organizer Proteins in Health and Disease 2020
602 CELLPHASE_AD Genetics to understand cellular components of Alzheimer Disease pathogenesis 2019
603 ConflictResolution Transcription-replication conflicts in disease and development 2020
604 AXONENDO Endosomal control of local protein synthesis in axons 2020
605 GO-DS21 Gene overdosage and comorbidities during the early lifetime in Down Syndrome 2020
606 PainFACT Molecular Mechanisms Associating Chronic Pain with Fatigue, Affective Disorders, Cardiovascular Disease and Total Comorbidity 2020
607 PROTEOFIT Adapting protein fate for muscle function and fitness 2019
608 PLASTINET Plasticity of the Pluripotency Network 2020
609 BIND Brain Involvement iN Dystrophinopathies 2020
610 MUSMICRO Causes and consequences of variation in the mammalian microbiota 2020
611 MInfla-Tilc Generation of therapeutic antibodies targeting type 2 Innate Lymphoid cells in asthma 2020
612 DPR-VAX Dipeptide-Repeat Vaccine to prevent ALS and FTD in C9orf72 mutation carriers 2020
613 AgingTimer Systems biology of the individual stochastic timer of aging 2020
614 CLAUSTROFUNCT Claustrum function in cortical processing and putative claustral dysfunction in schizophrenia 2020
615 CELPRED Circuit elements of the cortical circuit for predictive processing 2020
616 PHYRIST Physiological roles of the Ribotoxic Stress Response 2020
617 lncImpact Long noncoding RNAs: Impact on Gene Regulatory Networks 2020
618 MyeRIBO Deconstructing the Translational Control of Myelination by Specialized Ribosomes 2020
619 TrojanDC Harnessing dendritic cell reprogramming for cancer immunotherapy 2020
620 REpAIR Spatio-Temporal Regulation of Inflammation and Tissue Regeneration: Studying the immune system - tissue - microbiota communication to develop targeted therapies for immune-mediated diseases and cancer 2020
621 SweetVision Envisioning the Reward: Neuronal circuits for goal-directed learning 2020
622 ALTER-brain Metastasis-associated altered molecular patterns in the brain 2020
623 CollectiveDynamics Collective signaling oscillations in embryonic patterning – revealing underlying principles 2020
624 ACE-OF-SPACE Analysis, control, and engineering of spatiotemporal pattern formation 2020
625 Proteomes-in-3D Three-dimensional dynamic views of proteomes as a novel readout for physiological and pathological alterations 2020
626 Ru4EYE Ruthenium-based photoactivated chemotherapy against eye cancer 2020
627 ROMB Retina Organoid Mechanobiology 2020
628 OLI.VAS The Oligo-Vascular interface: understanding its properties and functions 2020
629 CAC-seq. Chemical assisted enrichment of 5-carboxycytosine that also allows for DNA sequencing at single base resolution. 2020
630 CTS-TEs-ADprogress Cell type-specific molecular analysis of epigenetic changes and transposable element derepression in Alzheimer's disease progression 2020
631 RARE MAPS Dynamic proteomic maps of stem cell-derived neurons as a mechanistic discovery pipeline for rare neurological disease 2020
632 HESSP Hippocampus Extracellular Space Simulator Project (HESSP) 2020
633 SERWOM Understanding Serotonergic Regulation of Working Memory 2020
634 SpaTime_AnTB Single-cell spatiotemporal analysis of Mycobacterium tuberculosis responses to antibiotics within host microenvironments 2020
635 C.A.R.E. OA Cross-linking Adenosine Receptors - Estrogen receptors for OA treatment 2021
636 Kidney-Treg Characterisation and impact of kidney-resident Tregs in kidney physiology and pathologies 2020
637 MY MITOCOMPLEX Functional relevance of mitochondrial supercomplex assembly in myeloid cells 2021
638 RE-GENESis GENome Editing and delivery Strategies for REcoding the mammalian genome 2020
639 MOBETA Motor cortical beta bursts for movement planning and evaluation: Mechanisms, functional roles, and development 2020
640 Nano-axo-syn Nanoscale organisation of axo-axonic synapses along the axon initial segment of cortical pyramidal neurons in health and disease. 2020
641 GlioTarget Inflaming the microenvironment of glioblastoma tumors by ADAR1 inhibition: a two-hit approach for the treatment of brain cancer. 2021
642 VacTrack Dissecting the protection mechanism of new generation vaccines by synchronizing systems biology with in vivo imaging 2021
643 DEFINE DEciphering mechanisms of presynaptic reFINEment 2020
644 MacrophageEGR Egr1 and Egr2 regulate opposite transcriptional programs in macrophages 2021
645 FluAttack Validation of a novel antiviral drug candidate against influenza 2020
646 PFCmap Development of neural circuits in the prefrontal cortex 2020
647 StartAct Controlling forelimb actions through basal ganglia to brainstem signaling 2021
648 InProSMod Cholinergic and NMDAR-dependent recruitment of Layer 1 Interneuron shapes cortical motor Processing through network States Modulation 2021
649 SPHERES Lipid droplet hypertrophy : the link between adipocyte dysfunction and cardiometabolic diseases 2020
650 NEUROPREG Eating patterns in pregnancy: unraveling the underlying neurocircuits and its deleterious metabolic consequences 2021
651 OPEN P-CAN Dissecting the role of mitochondrial dynamics in pancreatic carcinogenesis 2020
652 SIGNAL Sensing Neuro-immune Activation in the Lung microenvironment 2020
653 TETCOLON Dissecting the role of the epigenetic regulator TET2 in colorectal cancer 2020
654 MRTFSen MRTF/SRF signalling in regulation of cell senescence and melanoma progression 2020
655 Ctrl-BBB Blood-brain barrier: from molecular mechanisms to intervention strategies 2020