MOLFACTORY

Towards a ‘molecular factory’: Processive sequence-selective synthesis with a synthetic molecular machine

Coordinatore	THE UNIVERSITY OF MANCHESTER    more  Organization address address: OXFORD ROAD city: MANCHESTER postcode: M13 9PL contact info Titolo: Ms. Nome: Liz Cognome: Fay Email: send email Telefono: 441613000000
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	231˙283 €
EC contributo	231˙283 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2012-IEF
Funding Scheme	MC-IEF
Anno di inizio	2013
Periodo (anno-mese-giorno)	2013-03-01   -   2015-02-28

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	THE UNIVERSITY OF MANCHESTER  Organization address address: OXFORD ROAD city: MANCHESTER postcode: M13 9PL contact info Titolo: Ms. Nome: Liz Cognome: Fay Email: send email Telefono: 441613000000	UK (MANCHESTER)	coordinator	231˙283.20

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 Obiettivo del progetto (Objective)

'The aim of this project is to construct a synthetic molecular machine that is capable of performing a complex task, chemical synthesis, far beyond the current state-of-the-art. Our target is to mimic translation, the process through which protein is synthesized on the mRNA template by the ribosome. Although biology uses threaded molecular architectures to transfer chemical information during sequence-specific oligomer and polymer assembly, such processes are yet to be reproduced in artificial small-molecule systems. The successful realization of the project will mark a major breakthrough in the development of artificial molecular machines that can perform real tasks at the molecular level including, ultimately, the synthesis of unnatural sequence specific oligomers and polymers that are not accessible by other routes.'