SPECFIN

Spectral Fingerprints of Neuronal Interactions

 Coordinatore EBERHARD KARLS UNIVERSITAET TUEBINGEN 

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 Nazionalità Coordinatore Germany [DE]
 Totale costo 1˙494˙480 €
 EC contributo 1˙494˙480 €
 Programma FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call ERC-2013-StG
 Funding Scheme ERC-SG
 Anno di inizio 2015
 Periodo (anno-mese-giorno) 2015-01-01   -   2019-12-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    EBERHARD KARLS UNIVERSITAET TUEBINGEN

 Organization address address: GESCHWISTER-SCHOLL-PLATZ
city: TUEBINGEN
postcode: 72074

contact info
Titolo: Dr.
Nome: Markus
Cognome: Siegel
Email: send email
Telefono: 4970710000000
Fax: 4970710000000

DE (TUEBINGEN) hostInstitution 1˙494˙480.00
2    EBERHARD KARLS UNIVERSITAET TUEBINGEN

 Organization address address: GESCHWISTER-SCHOLL-PLATZ
city: TUEBINGEN
postcode: 72074

contact info
Titolo: Ms.
Nome: Susanne
Cognome: Stoppel
Email: send email
Telefono: 4970710000000
Fax: +49 7071295784

DE (TUEBINGEN) hostInstitution 1˙494˙480.00

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invasive    brain    interactions    largely    human    oscillations    monkeys    framework    recordings    monkey    circuit    cortical    neuronal    underlying    electrophysiology    fingerprints    spectral    elementary    eeg    cognitive   

 Obiettivo del progetto (Objective)

'How does cognition result from complex neuronal interactions within and between brain regions? Substantial progress has been made understanding the functional properties of individual neurons, but we lack understanding of how they work together. Neuronal oscillations are ubiquitous in the brain. The frequencies of these oscillations reflect the biophysical properties of underlying circuit interactions. Thus, frequency-specific oscillations may serve as ‘spectral fingerprints’ of specific circuit interactions. However so far, the circuit interactions underlying cortical oscillations are largely unknown. The key objective of my proposal is to establish this ‘spectral fingerprint’ framework for the human brain, by identifying elementary circuit interactions underlying non-invasive M/EEG oscillations. We will employ a novel interdisciplinary approach that tightly links human and monkey electrophysiology. First, we will perform directly comparable EEG (and MEG) recordings in humans and monkeys using identical behavioural tasks to identify consistent local and large-scale oscillations in both species. Second, we will characterize the neuronal circuit interactions underlying these non-invasive oscillations in monkeys using simultaneous EEG and intra-cortical recordings as well as electrical and pharmacological manipulations. If successful, this work will constitute a paradigm shift in cognitive neuroscience by linking two largely disconnected disciplines: human and monkey electrophysiology. Identifying spectral fingerprints of elementary circuit interactions will establish a powerful new framework to understand cognitive processes in terms of mechanistic, network-level building blocks.'

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