AVERT-IT

Advanced Arterial Hypotension Adverse Event prediction through a Novel Bayesian Neural Network

Coordinatore	PERA INNOVATION LIMITED    more  Organization address address: Innovation Park, Nottingham Road city: Melton Mowbray, Leicestershire postcode: LE13 0BP contact info Titolo: Mr. Nome: Andrew Cognome: Dean Email: send email Telefono: 441665000000 Fax: 441665000000
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	2˙265˙890 €
EC contributo	1˙780˙000 €
Programma	FP7-ICT Specific Programme "Cooperation": Information and communication technologies
Code Call	FP7-ICT-2007-1
Funding Scheme	CP
Anno di inizio	2008
Periodo (anno-mese-giorno)	2008-01-01   -   2011-07-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	PERA INNOVATION LIMITED  Organization address address: Innovation Park, Nottingham Road city: Melton Mowbray, Leicestershire postcode: LE13 0BP contact info Titolo: Mr. Nome: Andrew Cognome: Dean Email: send email Telefono: 441665000000 Fax: 441665000000	UK (Melton Mowbray, Leicestershire)	coordinator	0.00
2	AZIENDA OSPEDALIERA SAN GERARDO DI MONZA  Organization address address: VIA PERGOLESI city: MONZA postcode: 20052 contact info Titolo: Dott. Nome: Mario Cognome: Caspani Email: send email Telefono: +39 039 2339753 Fax: +39 039 2339032	IT (MONZA)	participant	0.00
3	C3 GLOBAL LIMITED  Organization address address: DRUIMCHAT VIEW - DINGWALL BUSINESS PARK city: DINGWALL postcode: IV15 9XL contact info Titolo: Mrs Nome: Lorraine Cognome: McLeod Email: send email Telefono: +44 1349 865554 Fax: +44 1349 865558	UK (DINGWALL)	participant	0.00
4	GREATER GLASGOW HEALTH BOARD  Organization address address: DALIAN HOUSE, 350 ST VINCENT STREET city: GLASGOW postcode: G3 8YZ contact info Titolo: Mrs Nome: Sonia Cognome: Whyte Email: send email Telefono: +44 141 2011890 Fax: +44 141 2012060	UK (GLASGOW)	participant	0.00
5	INSTITUT CATALA DE LA SALUT  Organization address address: GRAN VIA DE LES CORTS CATALANES 587 city: BARCELONA postcode: 8007 contact info Titolo: Dr Nome: Juan E. Cognome: Feliu Email: send email Telefono: +34 934 894 337 Fax: +34 934 894 102	ES (BARCELONA)	participant	0.00
6	KAUNO TECHNOLOGIJOS UNIVERSITETAS  Organization address address: K DONELAICIO city: KAUNAS postcode: 44029 contact info Titolo: Prof. Nome: Arminas Cognome: Ragauskas Email: send email Telefono: +37 037 736897 Fax: +37 037 736897	LT (KAUNAS)	participant	0.00
7	PHILIPS MEDIZIN SYSTEME BOBLINGEN GMBH  Organization address address: HEWLETT-PACKARD-STRASSE 2 city: BOBLINGEN postcode: 71034 contact info Titolo: Mr Nome: Hubert Cognome: Volker Email: send email Telefono: +497031 4631325 Fax: +497031 463 2775	DE (BOBLINGEN)	participant	0.00
8	UNIVERSITAETSKLINIKUM HEIDELBERG  Organization address address: IM NEUENHEIMER FELD 672 city: HEIDELBERG postcode: 69120 contact info Titolo: Mr Nome: Uwe Cognome: Dietsch Email: send email Telefono: +49 6221 567082 Fax: +49 62215633670	DE (HEIDELBERG)	participant	0.00
9	UNIVERSITY OF GLASGOW  Organization address address: University Avenue city: GLASGOW postcode: G12 8QQ contact info Titolo: Mr Nome: Joseph Cognome: Galloway Email: send email Telefono: +44 141 3303884 Fax: +44 141 3305611	UK (GLASGOW)	participant	0.00
10	UPPSALA UNIVERSITET  Organization address address: St Olofsgatan city: UPPSALA postcode: 751 05 contact info Titolo: Ms Nome: Maude Cognome: Karlsdotter Email: send email Telefono: +46 18 614969 Fax: +46 18 558617	SE (UPPSALA)	participant	0.00

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 Obiettivo del progetto (Objective)

Hypotension (sub-normal blood pressure) adverse events (AE's) occur commonly in patients managed in intensive care and high dependency units. Health care technology which could reduce the burden of these events by as little as ten percent would equate to at least five billion Euros p.a. saved by European healthcare organisations for use in other treatment regimensnnThe AVERT-IT project will create a novel bed-side monitoring and alerting system dedicated to the prediction of variations in the condition of the patient that are likely to lead to hypotension without appropriate clinical intervention. A world-class consortium consisting of an SME software developer (C3 Global), renown clinical experts (www.brainit.org), Philips medical and Grid experts in secure access to distributed medical datasets will develop and validate the innovative technology using access to a unique and large repository of detailed multi-media patient data drawn from 22 clinical centres in 11 countries created through two recent EC funded projects.nnA systematic work programme will select appropriate clinical and monitoring inputs (via undertaking data mining and robust statistical analysis of this unique database and other electronic health record systems) to train a novel Bayesian Artificial Neural Network (BANN) to predict subsequent hypotension AE's. The BANN will form the engine of a novel IT-based decision support system ('HypoPredict') which will be prospectively validated in 6 clinical intensive care centres using a phase II clinical trial design.nnThe AVERT-IT project will produce a step-change in arterial hypotension prediction within the critical, intensive and high-dependency care environment with a major impact upon health care costs in terms of reduced corrective care, obviated as a consequence of the improved prediction of, and earlier intervention in, hypotension adverse events, and in improved patient outcome with associated reduction in carer-burden.