BIOHYPO
Confronting the clinical relevance of biocide induced antibiotic resistance
| Coordinatore | UNIVERSITA' DEGLI STUDI DI SIENA
Organization address
address: VIA BANCHI DI SOTTO 55 contact info |
| Nazionalità Coordinatore | Italy [IT] |
| Sito del progetto | http://kdbio.inesc-id.pt/biohypo/ |
| Totale costo | 4˙396˙589 € |
| EC contributo | 2˙999˙705 € |
| Programma | FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology |
| Code Call | FP7-KBBE-2008-2B |
| Funding Scheme | CP-FP |
| Anno di inizio | 2009 |
| Periodo (anno-mese-giorno) | 2009-06-01 - 2012-11-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
UNIVERSITA' DEGLI STUDI DI SIENA
Organization address
address: VIA BANCHI DI SOTTO 55 contact info |
IT (SIENA) | coordinator | 473˙856.00 |
| 2 |
QUOTIENT BIORESEARCH
Organization address
address: Newmarket Road contact info |
UK (FORDHAM) | participant | 280˙200.00 |
| 3 |
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Organization address
address: CALLE SERRANO 117 contact info |
ES (MADRID) | participant | 279˙945.00 |
| 4 |
ISTITUTO SUPERIORE DI SANITA
Organization address
address: Viale Regina Elena 299 contact info |
IT (ROMA) | participant | 274˙716.00 |
| 5 |
INESC ID - INSTITUTO DE ENGENHARIA DE SISTEMAS E COMPUTADORES, INVESTIGACAO E DESENVOLVIMENTO EM LISBOA
Organization address
address: AVENIDA ALVES REDOL 9 contact info |
PT (S JOAO DE DEUS LISBOA) | participant | 271˙824.00 |
| 6 |
Nome Ente NON disponibile
Organization address
address: "PARC CIENTIFIC DE BARCELONA, CALLE BALDIRI REIXAC 4-6" contact info |
ES (BARCELONA) | participant | 223˙600.00 |
| 7 |
UNIVERSITAET BERN
Organization address
address: Hochschulstrasse 4 contact info |
CH (BERN) | participant | 218˙400.00 |
| 8 |
GAZI UNIVERSITESI
Organization address
address: GAZI UNIVERSITESI GOLBASI YERLESKESI NANOTIP ARASTIRMA MERKEZI BAHCELIEVLER MAHALLESI 160 contact info |
TR (ANKARA) | participant | 218˙398.00 |
| 9 |
UNIVERSITA DEGLI STUDI DI MILANO
Organization address
address: Via Festa Del Perdono 7 contact info |
IT (MILANO) | participant | 217˙866.00 |
| 10 |
MIDDLE EAST TECHNICAL UNIVERSITY
Organization address
address: DUMLUPINAR BULVARI 1 contact info |
TR (ANKARA) | participant | 193˙200.00 |
| 11 |
UNIVERSITA DEGLI STUDI DI FIRENZE
Organization address
address: Piazza San Marco 4 contact info |
IT (Florence) | participant | 180˙000.00 |
| 12 |
Lysoform Dr. Hans Rosemann GmbH
Organization address
address: Kaiser-Wilhelm-Strasse 133 contact info |
DE (Berlin) | participant | 100˙200.00 |
| 13 |
AAT-ADVANCED ANALYTICAL TECHNOLOGIES
Organization address
address: Via Martiri della Resistenza-Galleria San Giuseppe 1 contact info |
IT (PIACENZA) | participant | 67˙500.00 |
Mappa
Word cloud
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Obiettivo del progetto (Objective)
'Biocides have been in use for hundreds of years for antisepsis, disinfection and preservation. Despite this widespread and ever increasing use most bacterial and fungal species remain susceptible to biocides. The dramatic increase and spread of resistance to antibiotics linked to reports of co- and cross-resistance between antibiotics and biocides raised speculations on potential hazard of biocide use. The overarching question which BIOHYPO is aimed to address is: has the use of biocides contributed to the development and spread of clinically significant antibiotic resistance in human pathogens? Core of BIOHYPO are a high throughput screening approach on collections of thousands of well characterized microorganisms and an interactive web based data analysis platform. Phenotypic screening for reduced susceptibility to biocides, detection of novel resistance genes and mobile elements, and screening for their molecular epidemiology and metagenomics will be accompanied by methodological innovation for testing, risk evaluation and registration of biocides. Altogether BIOHYPO aims to provide solid data and analysis to direct future issuing of guidelines for safe environmental, medical and industrial use of biocides.'
Introduzione (Teaser)
Biocides have long been used for antisepsis with high efficacy. Increasing speculation about biocide overuse being linked to antibiotic resistance has urged European scientists to perform a thorough investigation of this hypothesis.